Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Metin Turkay"'
Autor:
Seref Gul, Yasemin Kubra Akyel, Zeynep Melis Gul, Safak Isin, Onur Ozcan, Tuba Korkmaz, Saba Selvi, Ibrahim Danis, Ozgecan Savlug Ipek, Fatih Aygenli, Ali Cihan Taskin, Büşra Aytül Akarlar, Nurhan Ozlu, Nuri Ozturk, Narin Ozturk, Durişehvar Özer Ünal, Mustafa Guzel, Metin Turkay, Alper Okyar, Ibrahim Halil Kavakli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Cryptochromes are transcriptional regulators of the circadian clock in mammals, and genetic loss of cryptochromes reduces p53-associated cancer risk in mice. Here the authors report the discovery of small molecule M47, which destabilizes cryptochrome
Externí odkaz:
https://doaj.org/article/74ebf0d9b13b4f24b201b187236a7cc6
Structure-based design and classifications of small molecules regulating the circadian rhythm period
Autor:
Seref Gul, Fatih Rahim, Safak Isin, Fatma Yilmaz, Nuri Ozturk, Metin Turkay, Ibrahim Halil Kavakli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Circadian rhythm is an important mechanism that controls behavior and biochemical events based on 24 h rhythmicity. Ample evidence indicates disturbance of this mechanism is associated with different diseases such as cancer, mood disorders,
Externí odkaz:
https://doaj.org/article/53751473eb374211a46f13f33d21e0bd
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14579 (2011)
BackgroundAn important use of data obtained from microarray measurements is the classification of tumor types with respect to genes that are either up or down regulated in specific cancer types. A number of algorithms have been proposed to obtain suc
Externí odkaz:
https://doaj.org/article/8c2a87a5c48b446aadcaf6de57ab9676
Publikováno v:
Corporate Governance and Sustainability Review. 7:43-69
Sustainable operations are becoming important for companies, after the United Nations 2030 agenda that emerges countries to move toward sustainable development. Taking care of the environment, society, local communities, and related stakeholders are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5cd6042e71e01439b2b2b7c76b8872d
https://doi.org/10.22495/cgsrv7i1p4
https://doi.org/10.22495/cgsrv7i1p4
Autor:
Metin Turkay, Abdulla Al-Hajri, Murat Kucukvar, Yigit Kazancoglu, Ahmed Al-Sulaiti, Nuri Cihat Onat, Hussein Al-Yafei, Saleh Aseel
Publikováno v:
Sustainable Production and Consumption. 27:1602-1613
The demand for Liquefied Natural Gas (LNG) in the global markets has changed significantly. As a result, industries have been forced to consider investing significantly in supply chains to achieve an efficient distribution of LNG for cost efficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e27ebe9874d0ff0daecd26d650b5a17
https://doi.org/10.1016/j.spc.2021.04.002
https://doi.org/10.1016/j.spc.2021.04.002
Autor:
Styliani Avraamidou, Metin Turkay, Iosif Pappas, Efstratios N. Pistikopoulos, Justin Katz, Baris Burnak, Burcu Beykal
Publikováno v:
Ind Eng Chem Res
Industrial process systems need to be optimized, simultaneously satisfying financial, quality and safety criteria. To meet all those potentially conflicting optimization objectives, multiobjective optimization formulations can be used to derive optim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac5da239490b8453a10e9feb607d1cd
https://doi.org/10.1021/acs.iecr.1c01175
https://doi.org/10.1021/acs.iecr.1c01175
Publikováno v:
IEEE Transactions on Fuzzy Systems. 28:1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317da3be02898ea213c7d91bfd7fbd07
https://doi.org/10.1109/tfuzz.2019.2959462
https://doi.org/10.1109/tfuzz.2019.2959462
The circadian rhythms are physiological, biochemical, and behavioral oscillations that cycle every 24 hours to anticipate the daily changes in the external environment. Disruption of the circadian clock in mammals results in increased susceptibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639ed3c104dd923f9d4e066c6b43230a
https://aperta.ulakbim.gov.tr/record/234378
https://aperta.ulakbim.gov.tr/record/234378
Autor:
Saba Selvi, Yasemin Kubra Akyel, Mustafa Guzel, Fatih Aygenli, Nuri Ozturk, Ali Cihan Taskin, Safak Isin, Durisehvar Ozer Unal, Ibrahim Danis, Metin Turkay, Ozgecan Savlug Ipek, Seref Gul, Zeynep Melis Gul, Narin Ozturk, Alper Okyar, Tuba Korkmaz, Ibrahim Halil Kavakli
Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous level of the CRY1 in mammals will affect circadian rhythm and the relation of such a decrease with apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a2d1288d0a764da3ba1cf2f8bf2a8d
https://doi.org/10.1101/2021.07.21.453206
https://doi.org/10.1101/2021.07.21.453206
Autor:
Seref Gul, Yasemin Kubra Akyel, Zeynep Melis Gul, Safak Isin, Onur Ozcan, Tuba Korkmaz, Saba Selvi, Ibrahim Danis, Ozgecan Savlug Ipek, Fatih Aygenli, Ali Cihan Taskin, Büşra Aytül Akarlar, Nurhan Ozlu, Nuri Ozturk, Narin Ozturk, Durişehvar Özer Ünal, Mustafa Guzel, Metin Turkay, Alper Okyar, Ibrahim Halil Kavakli
Publikováno v:
Nature Communications
Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals will affect circadian rhythm and the relation of such a decrease with apoptosis. Here, we di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a15ca742cbd52392b0eafb83cb5d0e
https://pubmed.ncbi.nlm.nih.gov/36347873
https://pubmed.ncbi.nlm.nih.gov/36347873