Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Metin Çetįn"'
Autor:
Ozge Saatci, Rashedul Alam, Kim-Tuyen Huynh-Dam, Aynur Isik, Meral Uner, Nevin Belder, Pelin Gulizar Ersan, Unal Metin Tokat, Burge Ulukan, Metin Cetin, Kubra Calisir, Mustafa Emre Gedik, Hilal Bal, Ozlem Sener Sahin, Yasser Riazalhosseini, Denis Thieffry, Daniel Gautheret, Besim Ogretmen, Sercan Aksoy, Aysegul Uner, Aytekin Akyol, Ozgur Sahin
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-14 (2024)
Abstract Tamoxifen has been the mainstay therapy to treat early, locally advanced, and metastatic estrogen receptor-positive (ER + ) breast cancer, constituting around 75% of all cases. However, the emergence of resistance is common, necessitating th
Externí odkaz:
https://doaj.org/article/736322c0c13e4be88e8c36818fc7c5ab
Autor:
Ozge Saatci, Metin Cetin, Meral Uner, Unal Metin Tokat, Ioulia Chatzistamou, Pelin Gulizar Ersan, Elodie Montaudon, Aytekin Akyol, Sercan Aksoy, Aysegul Uner, Elisabetta Marangoni, Mathew Sajish, Ozgur Sahin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Resistance to endocrine therapy and CDK4/6 inhibitors, the standard of care (SOC) in estrogen receptor-positive (ER+) breast cancer, greatly reduces patient survival. Therefore, elucidating the mechanisms of sensitivity and resistance to SOC
Externí odkaz:
https://doaj.org/article/12ad9995bcd94038ac3e1cc764cb8625
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionRenal artery stenosis in children is rare, and the recommended diagnostic algorithm, including techniques such as catheter-based angiography, CT angiography, magnetic resonance angiography, and ultrasound, is controversial in pediatric co
Externí odkaz:
https://doaj.org/article/53a68cf0fa764fd0bc1917c2223e8887
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionThe number of children with acute and chronic liver disease is rising. Moreover, liver involvement may be limited to subtle changes in organ texture especially in early childhood and some syndromic conditions, such as ciliopathies. Attenu
Externí odkaz:
https://doaj.org/article/aba94a9fafce4fe1a555e0508c21c9fe
Autor:
Metin Çetin
Publikováno v:
Şırnak Üniversitesi İlahiyat Fakültesi Dergisi, Iss 28, Pp 225-248 (2022)
Kur’ân’da geçen kelime ve kavramların detaylı bir şekilde incelenmesi, ilahi mesajın daha iyi anlaşılmasına katkıda bulunmaktadır. Bu açıdan son ilahi kitap olan Kur’ân da hedefini en iyi şekilde ifade edecek kavramları seçmiş
Externí odkaz:
https://doaj.org/article/666ec7629209499fb977b03a62a299dc
Autor:
Thao Nguyen, Lea Zillich, Metin Cetin, Alisha S. M. Hall, Jerome C. Foo, Lea Sirignano, Josef Frank, Tabea S. Send, Maria Gilles, Marcella Rietschel, Michael Deuschle, Stephanie H. Witt, Fabian Streit
Publikováno v:
Stress, Vol 26, Iss 1 (2023)
The COVID-19 pandemic severely affected the lives of families and the well-being of both parents and their children. Various factors, including prenatal stress, dysregulated stress response systems, and genetics may have influenced how the stress cau
Externí odkaz:
https://doaj.org/article/9a7841dd55dd4b7bbc13a822f6f772ec
Autor:
Wolfgang H. Ziegler, Sarah Lüdiger, Fatima Hassan, Margarita E. Georgiadis, Kathrin Swolana, Amrit Khera, Arne Mertens, Doris Franke, Kai Wohlgemuth, Mareike Dahmer-Heath, Jens König, Claudia Dafinger, Max C. Liebau, Metin Cetiner, Carsten Bergmann, Birga Soetje, Dieter Haffner
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background In pediatric hereditary cystic kidney diseases, epithelial cell defects mostly result from rare, autosomal recessively inherited pathogenic variants in genes encoding proteins of the cilia-centrosome complex. Consequences of indiv
Externí odkaz:
https://doaj.org/article/bfa8263fab9a4c9ab1d201733f2e6381
Autor:
Rahul Sreekumar, Hajir Al‐Saihati, Muhammad Emaduddin, Karwan Moutasim, Massimiliano Mellone, Ashish Patel, Seval Kilic, Metin Cetin, Sule Erdemir, Marta Salgado Navio, Maria Antonette Lopez, Nathan Curtis, Tamer Yagci, John N. Primrose, Brendan D. Price, Geert Berx, Gareth J. Thomas, Eugene Tulchinsky, Alex Mirnezami, A. Emre Sayan
Publikováno v:
Molecular Oncology, Vol 15, Iss 8, Pp 2065-2083 (2021)
Resistance to adjuvant chemotherapy is a major clinical problem in the treatment of colorectal cancer (CRC). The aim of this study was to elucidate the role of an epithelial to mesenchymal transition (EMT)‐inducing protein, ZEB2, in chemoresistance
Externí odkaz:
https://doaj.org/article/48e36438327a4d3b9ecc9732d773fccf
Autor:
Emrah Özçelik, Ahmet Kalaycı, Büşra Çelik, Açelya Avcı, Hasan Akyol, İrfan Baki Kılıç, Türkan Güzel, Metin Çetin, Merve Tuzlakoğlu Öztürk, Zihni Onur Çalışkaner, Melike Tombaz, Dilan Yoleri, Özlen Konu, Ayten Kandilci
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0275476 (2022)
DEK has a short isoform (DEK isoform-2; DEK2) that lacks amino acid residues between 49-82. The full-length DEK (DEK isoform-1; DEK1) is ubiquitously expressed and plays a role in different cellular processes but whether DEK2 is involved in these pro
Externí odkaz:
https://doaj.org/article/12d8b3f3b29b44a38c024ce11afae005
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2018 (2018)
Background and Aims. Hepatocellular carcinoma is an aggressive malignancy of the liver and is ranked as the sixth most common cancer worldwide. There is still room for novel markers to improve the diagnosis and monitoring of HCC. Our observations in
Externí odkaz:
https://doaj.org/article/731dd873770f40cc9c6c2cdab222e648