Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Methyltransferase-like 3"'
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract Kidney disease is marked by complex pathological mechanisms and significant therapeutic hurdles, resulting in high morbidity and mortality rates globally. A deeper understanding of the fundamental processes involved can aid in identifying no
Externí odkaz:
https://doaj.org/article/4abe4ff08ac9403bb54007552a1824d8
Autor:
Qian Zhou, Xianyang Liu, Huiping Lu, Na Li, Jiayu Meng, Jiaxing Huang, Zhi Zhang, Jiangyi Liu, Wei Fan, Wanqian Li, Xingran Li, Xiaoyan Liu, Hangjia Zuo, Peizeng Yang, Shengping Hou
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Retinal neovascularization (RNV) disease is one of the leading causes of blindness, yet the molecular underpinnings of this condition are not well understood. To delve into the critical aspects of cell-mediated angiogenesis, we analyzed our
Externí odkaz:
https://doaj.org/article/4efaaede73cd4a619f0a6e11bb846fb1
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Diabetic retinopathy (DR) is a major ocular complication of diabetes mellitus, and a significant cause of visual impairment and blindness in adults. Phosphoserine aminotransferase 1 (PSAT1) is an enzyme participating in serine syn
Externí odkaz:
https://doaj.org/article/d7b3a1cad7484a03828795fbf63dd21b
Autor:
Qiuyun Wang, Jie Shen, Shiyuan Luo, Zhize Yuan, Shiyou Wei, Qiang Li, Qianzi Yang, Yan Luo, Lei Zhuang
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background The pathogenesis of acute lung injury (ALI) involves a severe inflammatory response, leading to significant morbidity and mortality. N6-methylation of adenosine (m6A), an abundant mRNA nucleotide modification, plays a crucial role
Externí odkaz:
https://doaj.org/article/ab8f943e16694b69ab55c42b2697fced
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-9 (2024)
Abstract Breast cancer (BC) is a highly prevalent malignancy worldwide, with complex pathogenesis and treatment challenges. Research reveals that methyltransferase-like 3 (METTL3) is widely involved in the pathogenesis of several tumors through methy
Externí odkaz:
https://doaj.org/article/79a5980b58314ab8add9520e6c83fa11
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Methyltransferase-like 3(METTL3), recognized as the primary N6-methyladenosine methyltransferase, influences cellular functions such as proliferation, migration, invasion, differentiation, and fate determination by regulating gene expression post-tra
Externí odkaz:
https://doaj.org/article/848f3dd25576455b8aa8d9845fd11b26
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117421- (2024)
Lung diseases have complex pathogenesis and treatment challenges, showing an obvious increase in the rate of diagnosis and death every year. Therefore, elucidating the mechanism for their pathogenesis and treatment ineffective from novel views is ess
Externí odkaz:
https://doaj.org/article/b66e3feae2de4ed8bc0556ad0f5ac0eb
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Cancer stem cells (CSCs) are a small population of less differentiated cells with robust self-renewal ability. CSCs have been recognized as the root cause of tumor initiation, progression, relapse, and drug resistance. Recent studies from us and othe
Externí odkaz:
https://doaj.org/article/1c842449d9ad4ed0be6db5ea24009c18
Autor:
Kamila Ostrowska, Agnieszka A. Rawłuszko-Wieczorek, Julia Ostapowicz, Wiktoria M. Suchorska, Wojciech Golusiński
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundRNA methyltransferase-like 3 (METTL3) is responsible for methyl group transfer in the progression of N6-methyladenosine (m6A) modification. This epigenetic feature contributes to the structural and functional regulation of RNA and consequen
Externí odkaz:
https://doaj.org/article/cddde8617a614c64954d950cd5204726
Publikováno v:
Chinese Journal of Lung Cancer, Vol 26, Iss 12, Pp 919-933 (2023)
Background and objective Lung cancer is a major threat to human health. The molecular mechanisms related to the occurrence and development of lung cancer are complex and poorly known. Exploring molecular markers related to the development of lung can
Externí odkaz:
https://doaj.org/article/a4f4fcf211694a6791e973dbd94ccec3