Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Methylation-driven genes"'
Publikováno v:
International Journal of General Medicine, Vol Volume 14, Pp 10541-10555 (2021)
Yiling Lu,1,* Weichun Tang,2,3,* Xiaoyu Wang,1 Xinyi Kang,1 Jun You,1 Liping Chen1 1Department of Obstetrics and Gynecology, Nantong First People’s Hospital, Nantong, Jiangsu, 226001, People’s Republic of China; 2NHC Key Laboratory of Ant
Externí odkaz:
https://doaj.org/article/fb7fe4c892be45aab6340effe5c86cbc
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background The potential reversibility of aberrant DNA methylation indicates an opportunity for oncotherapy. This study aimed to integrate methylation-driven genes and pretreatment prognostic factors and then construct a new individual progn
Externí odkaz:
https://doaj.org/article/8ca9bab32baa46bd834d635f49ac4bd2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Accumulating evidence suggests that DNA methylation has essential roles in the development of renal cell carcinoma (RCC). Aberrant DNA methylation acts as a vital role in RCC progression through regulating the gene expression, yet little is known abo
Externí odkaz:
https://doaj.org/article/932706833a124485843bb2be5ae0c4c5
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-19 (2020)
Abstract Background Recurrence remains a major obstacle to long-term survival of laryngeal squamous cell carcinoma (LSCC). We conducted a genome-wide integrated analysis of methylation and the transcriptome to establish methylation-driven genes progn
Externí odkaz:
https://doaj.org/article/8e3c62686dc34d2a9161da3bc1897cb1
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Aberrant DNA methylation patterns are involved in the pathogenesis of papillary renal cell carcinoma (pRCC). This study aimed to investigate the potential of methylation-driven genes as biomarkers in determining the prognosis of p
Externí odkaz:
https://doaj.org/article/e306fa787a7f4f0d84af05010d43d1b9
Publikováno v:
Cancer Medicine, Vol 9, Iss 2, Pp 768-782 (2020)
Abstract Background To explore important methylation‐driven genes (MDGs) and risk loci to construct risk model for prognosis of bladder cancer (BCa). Methods We utilized TCGA‐Assembler package to download 450K methylation data and corresponding t
Externí odkaz:
https://doaj.org/article/fa48ecd133bc46d5a114ead8b57784ba
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Biochemical recurrence (BCR) after radical prostatectomy indicates poor prognosis in patients with prostate cancer (PCA). DNA methylation (DNAm) is a critical factor in tumorigenesis and has attracted attention as a biomarker for the diag
Externí odkaz:
https://doaj.org/article/394a457a106a4a018406c1aba4858541
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Low-grade gliomas (LGG) are heterogeneous, and the current predictive models for LGG are either unsatisfactory or not user-friendly. The objective of this study was to establish a nomogram based on methylation-driven genes, combined with clinicopatho
Externí odkaz:
https://doaj.org/article/495fd464bbb2420b9df9429641a76c3b
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundGlioblastoma multiforme (GBM) is characterized by widespread genetic and transcriptional heterogeneity. Aberrant DNA methylation plays a vital role in GBM progression by regulating gene expression. However, little is known about the role of
Externí odkaz:
https://doaj.org/article/bdb6b4a0d9f2450fa130c0039d8c330c
Autor:
Hao Huang, Jinming Fu, Lei Zhang, Jing Xu, Dapeng Li, Justina Ucheojor Onwuka, Ding Zhang, Liyuan Zhao, Simin Sun, Lin Zhu, Ting Zheng, Chenyang Jia, Binbin Cui, Yashuang Zhao
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundAberrant DNA methylation is a critical regulator of gene expression and plays a crucial role in the occurrence, progression, and prognosis of colorectal cancer (CRC). We aimed to identify methylation-driven genes by integrative epigenetic a
Externí odkaz:
https://doaj.org/article/49d1e4df83414642b06c21ce024afb2d