Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Methylation of DNA"'
Traversing the epigenetic landscape: DNA methylation from retina to brain in development and disease
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
DNA methylation plays a crucial role in development, aging, degeneration of various tissues and dedifferentiated cells. This review explores the multifaceted impact of DNA methylation on the retina and brain during development and pathological proces
Externí odkaz:
https://doaj.org/article/80374ae64f6041c796a30f95c50549e7
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background In a heterogeneous population of cells, individual cells can behave differently and respond variably to the environment. This cellular diversity can be assessed by measuring DNA methylation patterns. The loci with variable methyla
Externí odkaz:
https://doaj.org/article/69536a4634364532bc7e73d9cfb27cf4
Akademický článek
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Autor:
Herlanny Santana Bezerra, Caroline Severo de Assis, Mayara Karla dos Santos Nunes, Isabella Wanderley de Queiroga Evangelista, João Modesto Filho, Cecília Neta Alves Pegado Gomes, Rayner Anderson Ferreira do Nascimento, Rafaella Cristhine Pordeus Luna, Maria José de Carvalho Costa, Naila Francis Paulo de Oliveira, Darlene Camati Persuhn
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Background Polymorphisms in the gene encoding methylenetetrahydrofolate reductase (MTHFR) have been investigated as risk factors for microvascular complications of diabetes; however, simultaneous analysis of these polymorphisms and the methy
Externí odkaz:
https://doaj.org/article/338abb6677474b7b920412536f874484
Akademický článek
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Akademický článek
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Publikováno v:
Biologia Plantarum, Vol 60, Iss 4, Pp 628-634 (2016)
Little is known about the contributions of DNA methylation/demethylation to plant aging and senescence. We used Arabidopsis thaliana to study how increasing age of an annual plant species influences DNA methylation. Based on methylation-sensitive DNA
Externí odkaz:
https://doaj.org/article/1679d07afff5419481d1286ecaac4094
Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer
Autor:
Leonid S. Leskov, Alexander E. Kel, Manel Esteller, Olga V. Kel-Margoulis, Ulyana A. Boyarskikh, Sebastian Moran, Philip Stegmaier, Daria Stelmashenko, Anna Martínez-Cardús, Nikita Mandrik, Jeannette Koschmann, Edgar Wingender, Andrey Sokolov, Fedor A. Kolpakov, Ivan S. Yevshin, Mathias Krull, Maxim L. Filipenko
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S4, Pp 1-20 (2019)
BMC Bioinformatics
BMC Bioinformatics
Background The search for molecular biomarkers of early-onset colorectal cancer (CRC) is an important but still quite challenging and unsolved task. Detection of CpG methylation in human DNA obtained from blood or stool has been proposed as a promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d42cc2870eb3549008c9452f0b637c
http://link.springer.com/article/10.1186/s12859-019-2687-7
http://link.springer.com/article/10.1186/s12859-019-2687-7
Autor:
Salomão, Karina Bezerra
O imprinting genômico, processo regulado epigeneticamente segundo o qual os genes se expressam de acordo com sua origem parental (paterna ou materna), está envolvido no desenvolvimento placentário. Na região cromossômica 11p15.5 encontram-se vá
Autor:
Paolo Incardona, Pier Luigi Chiodera, Pietro Cavalli, Carlo Terenzio Paties, Fausto Zorzi, Marialuisa Crosatti, Eleonora Marchina, Edoardo Abeni, Arianna Coniglio, Giuseppina De Petro, Alessandro Salvi, Ilaria Grossi
Publikováno v:
Oncology Letters
In total, ~25% of familial breast cancer (BC) is attributed to germline mutations of the BRCA1 and BRCA2 genes, while the rest of the cases are included in the BRCAX group. BC is also known to affect men, with a worldwide incidence of 1%. Epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2ac69b7f91ac92d5e29b9f78d6e505
https://doi.org/10.3892/ol.2021.12729
https://doi.org/10.3892/ol.2021.12729