Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Methyl CpG-binding domain protein 2"'
Autor:
WU Dingjiang, ZHANG Xiufeng
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 8, Pp 1165-1169 (2024)
Severe asthma is a chronic inflammatory disease that is not sensitive to glucocorticoid treatment. In the pathogenesis of severe asthma, T helper cell 17(Th17) and interleukin 17 (IL-17) play an important role, mainly by aggregating the infiltration
Externí odkaz:
https://doaj.org/article/4c101f3740834bd5b691668392cebd41
Autor:
Zhifeng Chen, Yulin Shang, Yu Yuan, Yi He, Binaya Wasti, Wentao Duan, Ruoyun Ouyang, Jingsi Jia, Bing Xiao, Dongshan Zhang, Xiufeng Zhang, Jianmin Li, Bolin Chen, Yi Liu, Qingping Zeng, Xiaoying Ji, Libing Ma, Shaokun Liu, Xudong Xiang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Objectives: .Asthma is a highly heterogeneous disease, and T-helper cell type 17 (Th17) cells play a pathogenic role in the development of non-T2 severe asthma. Misshapen like kinase 1 (MINK1) is involved in the regulation of Th17 cell differentiatio
Externí odkaz:
https://doaj.org/article/0bc2a2afb9a34baca915438d8a462c47
Publikováno v:
Di-san junyi daxue xuebao, Vol 41, Iss 10, Pp 955-960 (2019)
Objective To study whether methyl-CpG-binding domain protein 2 (MBD2) affects the expression of aquaporin-5 (AQP5) in human submandibular gland (HSG) cells, thereby exploring a new approach to treatment of Sjögren's syndrome (SS). Methods Cultured H
Externí odkaz:
https://doaj.org/article/c345860f677f422bbbfd9e355820cd16
Publikováno v:
International Journal of COPD, Vol Volume 13, Pp 703-715 (2018)
Zhilin Zeng,1,2 Miao Li,1 Jinkun Chen,3 Qinghai Li,1 Qin Ning,2 Jianping Zhao,1 Yongjian Xu,1 Jungang Xie,1 Jun Yu4 1Department of Respiratory and Critical Care Medicine, National Clinical Research Center of Respiratory Disease, 2Department of Infect
Externí odkaz:
https://doaj.org/article/3d5a851b4e2f49de8958e67098327f82
Autor:
Karachanak-Yankova S, Dimova R, Nikolova D, Nesheva D, Koprinarova M, Maslyankov S, Tafradjiska R, Gateva P, Velizarova M, Hammoudeh Z, Stoynev N, Toncheva D, Tankova T, Dimova I
Publikováno v:
Balkan Journal of Medical Genetics, Vol 18, Iss 2, Pp 15-24 (2015)
Epigenetic changes, in particular DNA methylation processes, play a role in the pathogenesis and progression of type 2 diabetes mellitus (T2DM) linking genetic and environmental factors. To clarify this role, we have analyzed in patients with differe
Externí odkaz:
https://doaj.org/article/31f50a2081884bcaa30445127999a09a
Publikováno v:
Oncology Letters
Platinum resistance is an important cause of clinical recurrence and mortality of patients with high-grade serous ovarian cancer (HGSOC). Methyl-CpG binding domain protein 2 (MBD2) serves an important role in tumor progression; however, its role in H
Akademický článek
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Autor:
Hunter McLeod, Daniel F. Clark, Kimberly R. Shorter, Nuri Smith, Whitnei Smith, Stewart Glenister, Nicole Rogers, Gabriel Castillo, Rahaf Al Sayed
Publikováno v:
Biochemistry and Biophysics Reports, Vol 20, Iss, Pp-(2019)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Many diseases are now associated with aberrant epigenetics and gene expression changes. Epigenetics can be modified by factors like diet. One dietary factor, folic acid, is consumed in various forms including supplements, energy drinks, and fortified
Autor:
Jungang Xie, Jinkun Chen, Zhilin Zeng, Qin Ning, Jianping Zhao, Qinghai Li, Jun Yu, Yongjian Xu, Miao Li
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Zhilin Zeng,1,2 Miao Li,1 Jinkun Chen,3 Qinghai Li,1 Qin Ning,2 Jianping Zhao,1 Yongjian Xu,1 Jungang Xie,1 Jun Yu4 1Department of Respiratory and Critical Care Medicine, National Clinical Research Center of Respiratory Disease, 2Department of Infect
Autor:
Yong-Kyung Choe, Bo Yeon Kim, Young-Jun Park, Suk Ran Yoon, Heesoo Lee, Seon-Jin Lee, Hee Gu Lee, Jong-Wan Kim, Tae Woo Kim, Byung Moo Oh, Jeong-Ki Min, Tae Gi Uhm
Publikováno v:
Oncotarget
Toll-like receptor 4 (TLR4) is important in promoting the immune response in various cancers. Recently, TLR4 is highly expressed in a stage-dependent manner in gastric cancer, but the regulatory mechanism of TLR4 expression has been not elucidated it