Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Methodios, Ximerakis"'
Autor:
Methodios Ximerakis, Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago, Xian Adiconis, Danielle Dionne, Lan Nguyen, Kavya M. Shah, Jill M. Goldstein, Caterina Gasperini, Ioannis A. Gampierakis, Scott L. Lipnick, Sean K. Simmons, Sean M. Buchanan, Amy J. Wagers, Aviv Regev, Joshua Z. Levin, Lee L. Rubin
Publikováno v:
Nature Aging. 3:327-345
Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8657f8805441eff3eb51264f9415b9f0
https://doi.org/10.1038/s43587-023-00373-6
https://doi.org/10.1038/s43587-023-00373-6
Autor:
Yassemi Koutmani, Ioannis A. Gampierakis, Alexia Polissidis, Methodios Ximerakis, Paraskevi N. Koutsoudaki, Alexandros Polyzos, George Agrogiannis, Sevasti Karaliota, Dimitra Thomaidou, Lee L. Rubin, Panagiotis K. Politis, Katia P. Karalis
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 932-945.e7 (2019)
Summary: Local cues in the adult neurogenic niches dynamically regulate homeostasis in neural stem cells, whereas their identity and associated molecular mechanisms remain poorly understood. Here, we show that corticotropin-releasing hormone (CRH), t
Externí odkaz:
https://doaj.org/article/4c2927ca07724a1996222ea2435ef2cb
Autor:
Methodios Ximerakis, Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago, Xian Adiconis, Danielle Dionne, Lan Nguyen, Kavya M. Shah, Jill M. Goldstein, Caterina Gasperini, Scott L. Lipnick, Sean K. Simmons, Sean M. Buchanan, Amy J. Wagers, Aviv Regev, Joshua Z. Levin, Lee L. Rubin
Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa15dde94ef8da6cad65bafb306b3bd
https://doi.org/10.1101/2022.01.27.477911
https://doi.org/10.1101/2022.01.27.477911
Autor:
Methodios Ximerakis
Κατά τα τελευταία χρόνια έχει καταστεί ολοένα και πιο σαφές ότι τα πρωτεϊνικά επίπεδα της α-συνουκλεΐνης παίζουν σημαντικό ρόλο στην πα
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8fed018a7d136a2df334240bbc45cb9
https://doi.org/10.12681/eadd/42062
https://doi.org/10.12681/eadd/42062
Autor:
Ruth Isserlin, Lan Nguyen, Vincent L. Butty, Joshua Z. Levin, Xian Adiconis, Methodios Ximerakis, Brittany A Mayweather, Ceren Ozek, Lee L. Rubin, Sean M. Buchanan, Sean Simmons, Scott Lipnick, Stuart S. Levine, Zachary Niziolek, Danielle Dionne, Brendan T. Innes, Aviv Regev, Gary D. Bader
Publikováno v:
Nature Neuroscience. 22:1696-1708
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how each cell type is affected in aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::150287e0ef93db6ff75e178ce2188bc2
https://doi.org/10.1038/s41593-019-0491-3
https://doi.org/10.1038/s41593-019-0491-3
Autor:
Xian Adiconis, Stuart S. Levine, Brittany A Mayweather, Ruth Isserlin, Scott Lipnick, Vincent L. Butty, Lan Nguyen, Lee L. Rubin, Danielle Dionne, Methodios Ximerakis, Ceren Ozek, Sean M. Buchanan, Sean Simmons, Joshua Z. Levin, Brendan T. Innes, Zachary Niziolek, Aviv Regev, Gary D. Bader
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how the brain is affected with aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c60c20399c61f2ce5f11971bb97f67
Autor:
Methodios, Ximerakis, Scott L, Lipnick, Brendan T, Innes, Sean K, Simmons, Xian, Adiconis, Danielle, Dionne, Brittany A, Mayweather, Lan, Nguyen, Zachary, Niziolek, Ceren, Ozek, Vincent L, Butty, Ruth, Isserlin, Sean M, Buchanan, Stuart S, Levine, Aviv, Regev, Gary D, Bader, Joshua Z, Levin, Lee L, Rubin
Publikováno v:
Nature neuroscience. 22(10)
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how each cell type is affected in aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da0e860102d58e106c1aae6eb44ab5f2
https://pubmed.ncbi.nlm.nih.gov/31551601
https://pubmed.ncbi.nlm.nih.gov/31551601
Publikováno v:
Experimental Neurobiology
Converging lines of evidence suggest that cell-to-cell transmission and the self-propagation of pathogenic amyloidogenic proteins play a central role in the initiation and the progression of several neurodegenerative disorders. This "prion-like" hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c848814751cd551bff51aef9a5503f76
https://doi.org/10.5607/en.2014.23.4.324
https://doi.org/10.5607/en.2014.23.4.324
Autor:
Ioannis A. Gampierakis, Katia Karalis, Alexia Polissidis, Paraskevi N. Koutsoudaki, Panagiotis K. Politis, Methodios Ximerakis, Lee L. Rubin, Alexandros Polyzos, Dimitra Thomaidou, Sevasti Karaliota, George Agrogiannis, Yassemi Koutmani
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 932-945.e7 (2019)
Summary: Local cues in the adult neurogenic niches dynamically regulate homeostasis in neural stem cells, whereas their identity and associated molecular mechanisms remain poorly understood. Here, we show that corticotropin-releasing hormone (CRH), t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc065b806a5e00b30c8d270d025fcd2
https://doi.org/10.1016/j.celrep.2019.09.037
https://doi.org/10.1016/j.celrep.2019.09.037
Autor:
Theodoros I. Roumeliotis, Georgios Pampalakis, Methodios Ximerakis, Leonidas Stefanis, Spiros D. Garbis, Kostas Vekrellis, Georgia Sotiropoulou, Vasia-Samantha Sykioti
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(7)
Recent evidence suggests that specific extracellular α-synuclein (α-syn) strains are implicated in the progression of Parkinson's disease (PD) pathology. It is plausible that deregulation in the normal processing of secreted α-syn may be a causati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7810b80ac73abd62e2c21acba8d235d
https://pubmed.ncbi.nlm.nih.gov/24723692
https://pubmed.ncbi.nlm.nih.gov/24723692