Evolution and Population Dynamics of Clonal Complex 152 Community-Associated Methicillin-Resistant Staphylococcus aureus

Autor: Aina Elisabeth Fossum Moen, Marc Stegger, Paal Skytt Andersen, Ivana Cirkovic, Frieder Schaumburg, Frédéric Laurent, Berit Lilje, Graeme R. Nimmo, Patricia Martins Simoes, Anne Tristan, Sara Mernelius, Sharmin Baig, Thor Bech Johannesen, Michael Z. David, Dominique S. Blanc, Anders Rhod Larsen, Iris Spiliopoulou, Beverly Egyir

Publikováno v: Baig, S, Rhod Larsen, A, Martins Simões, P, Laurent, F, Johannesen, T B, Lilje, B, Tristan, A, Schaumburg, F, Egyir, B, Cirkovic, I, Nimmo, G R, Spiliopoulou, I, Blanc, D S, Mernelius, S, Moen, A E F, David, M Z, Andersen, P S & Stegger, M 2020, ' Evolution and Population Dynamics of Clonal Complex 152 Community-Associated Methicillin-Resistant Staphylococcus aureus ', mSphere, vol. 5, no. 4, e00226-20 . https://doi.org/10.1128/mSphere.00226-20
mSphere, vol. 5, no. 4, pp. e00226-20
mSphere, Vol 5, Iss 4, p e00226-20 (2020)
mSphere, Vol 5, Iss 4 (2020)

Since the late 1990s, changes in the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) were recognized with the emergence of community-associated MRSA (CA-MRSA). CA-MRSA belonging to clonal complex 152 (CC152), carrying the small sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa237d664bcceeaa4f48aff32e2d8f7
https://doi.org/10.1128/msphere.00226-20

Methicillin-Resistant Staphylococcus aureus ST80 Clone: A Systematic Review

Autor: Jean-Philippe Lavigne, Assia Mairi, Abdelaziz Touati

Publikováno v: Toxins
Toxins, MDPI, 2020, 12 (2), pp.119. ⟨10.3390/toxins12020119⟩
Toxins, Vol 12, Iss 2, p 119 (2020)

This review assessed the molecular characterization of the methicillin-resistant Staphylococcus aureus (MRSA)-ST80 clone with an emphasis on its proportion of total MRSA strains isolated, PVL production, spa-typing, antibiotic resistance, and virulen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a4ddc675c0efa9c5eb255812cbac2a
https://hal.umontpellier.fr/hal-03350075/file/toxins-12-00119-v2.pdf

Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice

Autor: Harkins, Catriona P, Pichon, Bruno, Doumith, Michel, Parkhill, Julian, Westh, Henrik, Tomasz, Alexander, de Lencastre, Herminia, Bentley, Stephen D, Kearns, Angela M, Holden, Matthew TG

Publikováno v: Genome Biology, Vol 18, Iss 1, Pp 1-11 (2017)
Harkins, C P, Pichon, B, Doumith, M, Parkhill, J, Westh, H, Tomasz, A, de Lencastre, H, Bentley, S D, Kearns, A M & Holden, M T G 2017, ' Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice ', Genome Biology (Online Edition), vol. 18, 130 . https://doi.org/10.1186/s13059-017-1252-9
Genome Biology

SDB, JP and MTGH were supported by Wellcome Trust grant 098051. CPH was supported by Wellcome Trust grant number 104241/z/14/z. Bioinformatics and computational biology analyses were supported by the University of St Andrews Bioinformatics Unit, whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1c5b8daa79668f8b22c9cb38e8542d9f
http://link.springer.com/article/10.1186/s13059-017-1252-9

Synthesis of Antibacterial Nisin⁻Peptoid Hybrids Using Click Methodology

Autor: Bolt, Hannah L, Kleijn, Laurens H J, Martin, Nathaniel I, Cobb, Steven L, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery

Publikováno v: Molecules, 2018, Vol.23(7), pp.1566 [Peer Reviewed Journal]
Molecules
Molecules, Vol 23, Iss 7, p 1566 (2018)
Molecules, 23(7), 1566
Molecules, 23(7). Multidisciplinary Digital Publishing Institute (MDPI)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Volume 23
Issue 7

Antimicrobial peptides and structurally related peptoids offer potential for the development of new antibiotics. However, progress has been hindered by challenges presented by poor in vivo stability (peptides) or lack of selectivity (peptoids). Herei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc41bc1e0e9e0ade970991500b71ca3
https://doi.org/10.3390/molecules23071566

The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria

Autor: Thomas Vorup-Jensen, Marlene Fredborg, Michael Lykke Hvam, Rikke Louise Meyer, R.A. Murphy, Mihaela Gadjeva, Jens R. Nyengaard, Arne Möller, Stig Hill Christiansen, M. Wang, Sandra M. Skovdal, Kenneth A. Howard, Eskild Petersen, Jane C. Davies, Kristian Juul-Madsen, Uffe B. Skov Sørensen, Esben Axelgaard, Niels Nørskov-Lauritsen

Publikováno v: Hill Christiansen, S, Murphy, R A, Juul-Madsen, K, Fredborg, M, Hvam, M L, Axelgaard, E, Skovdal, S M, Meyer, R L, Sørensen, U B S, Möller, A, Nyengaard, J R, Nørskov-Lauritsen, N, Wang, M, Gadjeva, M, Howard, K A, Davies, J C, Petersen, E & Vorup-Jensen, T 2017, ' The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria ', Scientific Reports, vol. 7, 15653 . https://doi.org/10.1038/s41598-017-15969-3
Christiansen, S H, Murphy, R A, Juul-Madsen, K, Fredborg, M, Hvam, M L, Axelgaard, E, Skovdal, S M, Meyer, R L, Sorensen, U B S, Moeller, A, Nyengaard, J R, Norskov-Lauritsen, N, Wang, M, Gadjeva, M, Howard, K A, Davies, J C, Petersen, E & Vorup-Jensen, T 2017, ' The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria ', Scientific Reports, vol. 7, 15653 . https://doi.org/10.1038/s41598-017-15969-3
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports

Classic drug development strategies have failed to meet the urgent clinical needs in treating infections with Gram-negative bacteria. Repurposing drugs can lead to timely availability of new antibiotics, accelerated by existing safety profiles. Glati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99382febee1c7502b41664ee0b7018f
https://doi.org/10.1038/s41598-017-15969-3