Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Methaq Mueen Al-Kaabi"'
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 63, Iss 2, Pp 230-234 (2020)
Background: Specific cytokines are related to pathologically changed prostate, propose that the balance in cytokine differs in normal and pathological prostate. Of these cytokines the interleukins 10, due to its “pleiotropic” actions in inflammat
Externí odkaz:
https://doaj.org/article/303f4a7807ea4ee8a62c2eb95aa10fd5
Publikováno v:
Indian Journal of Forensic Medicine & Toxicology.
Background: cancer stem cells (CSC) are potential cause for recurrence, metastasis and resistance of tumorsto different therapeutic modalities like hormonal radiotherapy and chemotherapy. We investigated twoCSC markers (NANOG and CD 133) in normal, h
Autor:
Andrew R. Green, Emad A. Rakha, Carlos Caldas, Christopher C. Nolan, Ian O. Ellis, Sultan N Sonbul, Abir A. Muftah, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Methaq Mueen Al-Kaabi
Publikováno v:
Breast Cancer Research and Treatment
Background Although the prognostic value of Ki67 in breast cancer is well documented, using optimal cut-points for patient stratification, reproducibility of the scoring and interpretation of the results remains a matter of debate particularly when u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d370a76a7c197304507d4f38dfa038
Autor:
Andrew R. Green, Steve Chan, C. C. Nolan, Emad A. Rakha, Nouf Alsubhi, Ian O. Ellis, Dena A. Jerjees, Alaa T. Alshareeda, Methaq Mueen Al-Kaabi, Abir A. Muftah, Srinivasan Madhusudan, Eleanor Cornford
Publikováno v:
British Journal of Cancer
Background: Checkpoint kinase1 (CHK1), which is a key component of DNA-damage-activated checkpoint signalling response, may have a role in breast cancer (BC) pathogenesis and influence response to chemotherapy. This study investigated the clinicopath
Autor:
Andrew R. Green, Rezvan Abduljabbar, Laki Buluwela, Emad A. Rakha, Ola H. Negm, Abhik Mukherjee, Chun F. Lai, Methaq Mueen Al-Kaabi, Simak Ali, Abir A. Muftah, Patrick J. Tighe, Ian O. Ellis, Dena A. Jerjees
Publikováno v:
Breast cancer research and treatment. 150(3)
Peroxisome proliferator-activated receptor-gamma (PPARγ) is an adopted orphan receptor that belongs to the nuclear receptor superfamily of transcription factors. PPARγ is regarded as a differentiation factor and it plays an important role in regula
Autor:
Mohamed R. Hamed, Patrick J. Tighe, Methaq Mueen Al-Kaabi, Rezvan Abduljabbar, Dena A. Jerjees, Abhik Mukherjee, Emad A. Rakha, Simak Ali, Ian O. Ellis, Ola H. Negm, Lakjaya Buluwela, Andrew R. Green, Chun-Fui Lai
Publikováno v:
Breast cancer research and treatment. 150(2)
The glucocorticoid receptor (GR) is a member of the nuclear receptor superfamily of transcription factors, which exerts anti-proliferative and anti-apoptotic activities. The GR is expressed in a large proportion of breast cancer (BC) although levels
Autor:
M. Layth Alabdullah, Emad A. Rakha, Andrew R. Green, C. C. Nolan, Sameer Mirza, Methaq Mueen Al-Kaabi, Patrick J. Tighe, Vimla Band, Ian O. Ellis, Rezvan Abduljabbar, Ola H. Negm, Dena A. Jerjees, Mohamed R. Hameed, Abir A. Muftah
Publikováno v:
Breast cancer research and treatment. 150(1)
The mammalian target of rapamycin complex 1 (mTORC1) is a downstream of the PI3K/Akt pathway which affects cancer development. mTORC1 has many downstream signalling effectors that can enhance different cellular responses. This study aims to investiga
Autor:
Abir A. Muftah, Methaq Mueen Al-Kaabi, Ian O. Ellis, Muslim L. Alabdullah, Dena A. Jerjees, Emad A. Rakha, Andrew R. Green, C. C. Nolan, Rezvan Abduljabbar
Publikováno v:
Breast cancer research and treatment. 147(1)
The extracellular-regulated kinase (ERK) 1/2 is one of the members of the mitogen-activated protein kinases (MAPKs). MAPKs are transduction proteins that play a role in controlling diverse cellular functions including proliferation and survival. In b