Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Meth Jayatilake"'
Autor:
Shivani Bansal, Yaoxiang Li, Sunil Bansal, William Klotzbier, Baldev Singh, Meth Jayatilake, Vijayalakshmi Sridharan, José A. Fernández, John H. Griffin, Hartmut Weiler, Marjan Boerma, Amrita K. Cheema
Publikováno v:
Metabolites, Vol 14, Iss 5, p 245 (2024)
Exposure to ionizing radiation, accidental or intentional, may lead to delayed effects of acute radiation exposure (DEARE) that manifest as injury to organ systems, including the kidney, heart, and brain. This study examines the role of activated pro
Externí odkaz:
https://doaj.org/article/42a2683e6be948beab598818f29e7231
Autor:
Yaoxiang Li, Michael Girgis, Meth Jayatilake, Artur A. Serebrenik, Amrita K. Cheema, Michael D. Kaytor, Vijay K. Singh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract BIO 300, a pharmaceutical formulation of genistein, is being developed as a radiation countermeasure to treat hematopoietic acute radiation syndrome (H-ARS) and the delayed effects of acute radiation exposure (DEARE). Several studies have af
Externí odkaz:
https://doaj.org/article/1fd6a8a4d1f645938839e42b36f38314
Autor:
Charles P. Hinzman, Meth Jayatilake, Sunil Bansal, Brian L. Fish, Yaoxiang Li, Yubo Zhang, Shivani Bansal, Michael Girgis, Anton Iliuk, Xiao Xu, Jose A. Fernandez, John H. Griffin, Elizabeth A. Ballew, Keith Unger, Marjan Boerma, Meetha Medhora, Amrita K. Cheema
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Urinary extracellular vesicles (EVs) are a source of biomarkers with broad potential applications across clinical research, including monitoring radiation exposure. A key limitation to their implementation is minimal standardizati
Externí odkaz:
https://doaj.org/article/c5426affb3a14b0b9aa3b0ca913f86c2
Autor:
Raffaelle Girlanda, Jedson R. Liggett, Meth Jayatilake, Alexander Kroemer, Juan Francisco Guerra, Jason Solomon Hawksworth, Pejman Radkani, Cal S. Matsumoto, Michael Zasloff, Thomas M. Fishbein
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2079 (2022)
We analyzed the fecal microbiome by deep sequencing of the 16S ribosomal genes and the metabolomic profiles of 43 intestinal transplant recipients to identify biomarkers of graft function. Stool samples were collected from 23 patients with stable gra
Externí odkaz:
https://doaj.org/article/a5f1028a06e849a399308560397f120e
Autor:
Amrita K. Cheema, Yaoxiang Li, Michael Girgis, Meth Jayatilake, Oluseyi O. Fatanmi, Stephen Y. Wise, Thomas M. Seed, Vijay K. Singh
Publikováno v:
Metabolites, Vol 10, Iss 5, p 211 (2020)
Acute exposure to high-dose ionizing irradiation has the potential to severely injure the hematopoietic system and its capacity to produce vital blood cells that innately serve to ward off infections and excessive bleeding. Developing a medical radia
Externí odkaz:
https://doaj.org/article/5a9fdfffcdac4a538534f02e35566db0
Autor:
Kepher H. Makambi, Meth Jayatilake, Sirao Wang, Yaoxiang Li, Amrita K. Cheema, Kirandeep Gill, Vijayalakshmi Sridharan, Michael Girgis
Publikováno v:
J Environ Sci Health C Toxicol Carcinog
Molecular alterations as a result of exposure to low doses of high linear energy transfer (LET) radiation can have deleterious short- and long-term consequences on crew members embarking on long distance space missions. Oxygen ions ((16)O) are among
Autor:
Michael Girgis, Andrew G DeMarco, Kirandeep Gill, Sunil Bansal, Amrita K. Cheema, John B. Tyburski, Meth Jayatilake, Khyati Y. Mehta, Tixieanna Dissmore, Yaoxiang Li, Vijayalakshmi Sridharan, Shivani Bansal
Publikováno v:
J Environ Sci Health C Toxicol Carcinog
Astronauts embarking on deep space missions are at high risk of long-term exposure to low doses of high linear energy transfer (LET) radiation, which can contribute to the development of cancer and multiple degenerative diseases. However, long term e
Autor:
Meth Jayatilake, Elizabeth A Ballew, Yaoxiang Li, Michael Girgis, Monvadi B. Srichai, Celine Yeh, Ana Barac, Marjan Boerma, Keith Unger, Vijayalakshmi Sridharan, Amrita K. Cheema
Publikováno v:
Radiother Oncol
Purpose Although advancements in cancer treatments using radiation therapy (RT) have led to improved outcomes, radiation-induced heart disease (RIHD) remains a significant source of morbidity and mortality in survivors of cancers in the chest. Curren
Autor:
Evagelia C. Laiakis, Meth Jayatilake, Janet Gahagen, James Bakke, Kim Bujold, Albert J. Fornace, Denise Nishita, Polly Y. Chang, Simon Authier
Publikováno v:
Int J Radiat Oncol Biol Phys
PURPOSE: To identify metabolomic biomarkers of acute radiation exposure in saliva that show time-dependent changes. METHODS AND MATERIALS: Non-human primates (NHPs) were exposed to 4 Gy of total body irradiation with γ-rays. Saliva was collected fro
Autor:
Stephen Y. Wise, Michael Girgis, Thomas M. Seed, Meth Jayatilake, Yaoxiang Li, Oluseyi O. Fatanmi, Amrita K. Cheema, Vijay K. Singh
Publikováno v:
Metabolites
Volume 10
Issue 5
Metabolites, Vol 10, Iss 211, p 211 (2020)
Volume 10
Issue 5
Metabolites, Vol 10, Iss 211, p 211 (2020)
Acute exposure to high-dose ionizing irradiation has the potential to severely injure the hematopoietic system and its capacity to produce vital blood cells that innately serve to ward off infections and excessive bleeding. Developing a medical radia