Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Metalloproteinase Inhibitor 1"'
Autor:
S. A. Kryzhanovskii, G. V. Mokrov, Tatiana A Gudasheva, V. N. Stolyaruk, E. O. Ionova, I. B. Tsorin, M. B. Vititnova, O. S. Grigorkevich
Publikováno v:
Bulletin of Experimental Biology and Medicine. 168:641-645
Cardioprotective effect of 1-({4 [(4 chlorobenzoyl)amino]phenyl}sulfonyl-L-proline (compound AL-828) was studied in rats with modeled acute myocardial infarction. The test compound was administered intragastrically in a dose of 30 mg/kg/day for 3 day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b3e78aa15daddafa59c43fdec76770
https://doi.org/10.1007/s10517-020-04770-4
https://doi.org/10.1007/s10517-020-04770-4
Autor:
Barbara Górnicka, Christopher Kobierzycki, Marcin Chlebus, A. Cyganek, Barbara Grzechocińska, Miroslaw Wielgos, Filip A Dabrowski, Lukasz Michalowski
Publikováno v:
Folia Histochemica et Cytobiologica. 56:133-140
Introduction. Endometrium undergoes regular, cyclic tissue remodeling mostly associated to the endocrine system status. It is well-known fact that steroid hormones are strongly responsible for changes in endometrium. The precise mechanism of their ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cb6eee8916c12e19eb6f82271b943b
https://doi.org/10.5603/fhc.a2018.0017
https://doi.org/10.5603/fhc.a2018.0017
Autor:
Derek M. Erion, Xiaolun Wang, Tadahiro Nambu, Manami Kaneko, Kazunobu Aoyama, Mitsuharu Matsumoto, Mayumi Nishida, Hitomi Ogino, Hiroaki Yashiro, Sayuri Nakamura
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0228212 (2020)
PLoS ONE, Vol 15, Iss 1, p e0228212 (2020)
Acetyl-CoA carboxylase (ACC) catalyzes the rate-limiting step in de novo lipogenesis, which is increased in the livers of patients with nonalcoholic steatohepatitis. GS-0976 (firsocostat), an inhibitor of isoforms ACC1 and ACC2, reduced hepatic steat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03ee1a8026a9dc6125a90d7a01016e1
https://doi.org/10.1371/journal.pone.0228212
https://doi.org/10.1371/journal.pone.0228212
Publikováno v:
International Journal of Molecular Medicine
Parastomal hernia (PH) is a common complication following stoma formation. Abnormal collagen synthesis has been suggested to be involved in PH. The aim of the present study is to explore the effect and mechanism of the collagen synthesis on PH. Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80abfe687d8bf3db5204fa62d746446
https://pubmed.ncbi.nlm.nih.gov/31485641
https://pubmed.ncbi.nlm.nih.gov/31485641
Publikováno v:
Experimental and Therapeutic Medicine.
It has been demonstrated that 25-hydroxyvitamin-D3-24-hydroxylase (CYP24A1) is a key enzyme that neutralizes vitamin D activity, which may have an anti-tumor effect. Therefore, the aim of the current study was to explore the effect of the active meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1d9efa81711758500b9eab6cbd80c3
https://doi.org/10.3892/etm.2018.6536
https://doi.org/10.3892/etm.2018.6536
Publikováno v:
Molecular Medicine Reports.
Obesity and diabetes are characterized by low grade chronic inflammation status and insulin resistance in adipose tissue associated with metalloproteinase inhibitor 1 (TIMP1). Interleukin (IL)29, exhibits multiple immune regulatory activities. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252ca65c15dc9e05b0f83d224c073e8d
https://doi.org/10.3892/mmr.2018.8865
https://doi.org/10.3892/mmr.2018.8865
Autor:
Khaled Metwally, Eman Abdel Sameea, Tamer R. Fouad, Mona M. Aref, Nashwa Shible, Hassan Zaghla, Fatma A. Khalaf
Publikováno v:
Journal of Liver: Disease & Transplantation.
Background: Liver disease prevalence is high in Egypt and finding a reliable seromarker is needed for diagnosis and prognosis of fibrosis. Tissue inhibitor of metalloproteinase -1 (TIMP-1) previously showed a good relation with fibrosis but few data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3764ccfcf2eaaf488fc77348130c8559
https://doi.org/10.4172/2325-9612.1000157
https://doi.org/10.4172/2325-9612.1000157
Publikováno v:
Journal of Biological Chemistry. 286:42349-42359
Invasion and metastasis are the primary causes of breast cancer mortality, and increased knowledge about the molecular mechanisms involved in these processes is highly desirable. High levels of hyaluronan in breast tumors have been correlated with po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3c4bfdc114cbaa729a31cb4549ad64
https://doi.org/10.1074/jbc.m111.278598
https://doi.org/10.1074/jbc.m111.278598
Autor:
Charles E. Birse, Tao He, Jun Kim, Mark Han, William Fitzhugh, Erin Brand, Patrick Kaminker, Anh Nguyen, Mehdi Mesri, Gordon R. Nicol, Steven M. Ruben, Paul A. Moore
Publikováno v:
Molecular & Cellular Proteomics. 7:1974-1982
It is a challenging task to verify and quantify potential biomarkers expressed at elevated levels in sera from cancer patients. An immunoaffinity-mass spectrometry-based approach has been developed using antibodies to enrich proteins of interest from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabaf771be93b1c2a051e1b352de5c77
https://doi.org/10.1074/mcp.m700476-mcp200
https://doi.org/10.1074/mcp.m700476-mcp200
Autor:
Barbara Renga, Antonio Morelli, Andrea Mencarelli, Stefano Orlandi, Mark Pruzanski, Luisa Riccardi, Elisabetta Antonelli, Giovanni Rizzo, Stefano Fiorucci, Roberto Pellicciari
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 314:584-595
The farnesoid X receptor (FXR) is expressed by and regulates hepatic stellate cells (HSCs). In the present study, we investigated whether 6-ethyl chenodeoxycholic acid (6-ECDCA or INT-747), a semisynthetic derivative of chenodeoxycholic acid (CDCA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd968f22701c6d8007159d703ceddce
https://doi.org/10.1124/jpet.105.084905
https://doi.org/10.1124/jpet.105.084905