Zobrazeno 1 - 10
of 316
pro vyhledávání: '"Metallopeptidases"'
Autor:
F. Xavier Gomis-Rüth, Walter Stöcker
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
The astacins are a family of metallopeptidases (MPs) that has been extensively described from animals. They are multidomain extracellular proteins, which have a conserved core architecture encompassing a signal peptide for secretion, a prodomain or p
Externí odkaz:
https://doaj.org/article/f53d6c1bc77941aabec8067eb5f26591
Autor:
Rebecca Salomão, Victoria Assis, Ivo Vieira de Sousa Neto, Bernardo Petriz, Nicolas Babault, João Luiz Quaglioti Durigan, Rita de Cássia Marqueti
Publikováno v:
Biology, Vol 12, Iss 6, p 843 (2023)
MMPs are enzymes involved in SARS-CoV-2 pathogenesis. Notably, the proteolytic activation of MMPs can occur through angiotensin II, immune cells, cytokines, and pro-oxidant agents. However, comprehensive information regarding the impact of MMPs in th
Externí odkaz:
https://doaj.org/article/ece641a553924909937e0ccb94804578
Autor:
Graziela Vargas Rigo, Fernanda Gomes Cardoso, Matheus Mendonça Pereira, Michael Devereux, Malachy McCann, André L. S. Santos, Tiana Tasca
Publikováno v:
Pathogens, Vol 12, Iss 5, p 745 (2023)
Trichomonas vaginalis is responsible for 156 million new cases per year worldwide. When present asymptomatically, the parasite can lead to serious complications, such as development of cervical and prostate cancer. As infection increases the acquisit
Externí odkaz:
https://doaj.org/article/471b5edb6059449eb946dfcaf077010c
Autor:
Carina Jägers, Henk Roelink
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Sonic Hedgehog (Shh) has a catalytic cleft characteristic for zinc metallopeptidases and has significant sequence similarities with some bacterial peptidoglycan metallopeptidases defining a subgroup within the M15A family that, be
Externí odkaz:
https://doaj.org/article/e7d7b9a6fcfc40f3ab206856ccaa70fb
Publikováno v:
Archives of Medical Science, Vol 20, Iss 1, Pp 196-206 (2021)
Introduction Given the evidence that the matrix metalloproteinases (MMPs) play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD), a number of case-control studies have attempted to assess the relationship between g
Externí odkaz:
https://doaj.org/article/deaf1540f6a742ba8d4232d8bf43392b
Autor:
Tibisay Guevara, Arturo Rodriguez-Banqueri, Miroslaw Ksiazek, Jan Potempa, F. Xavier Gomis-Rüth
Publikováno v:
IUCrJ, Vol 7, Iss 1, Pp 18-29 (2020)
Tannerella forsythia is an oral dysbiotic periodontopathogen involved in severe human periodontal disease. As part of its virulence factor armamentarium, at the site of colonization it secretes mirolysin, a metallopeptidase of the unicellular pappaly
Externí odkaz:
https://doaj.org/article/25296af507af4334ad354c0e4cb88394
Akademický článek
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Autor:
Ana Amaral, Carina Fernandes, Sofia Morazzo, Maria Rosa Rebordão, Anna Szóstek-Mioduchowska, Karolina Lukasik, Barbara Gawronska-Kozak, Luís Telo da Gama, Dariusz Jan Skarzynski, Graça Ferreira-Dias
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Although proteases found in neutrophil extracellular traps (NETs) have antimicrobial properties, they also stimulate collagen type 1 (COL1) production by the mare endometrium, contributing for the development of endometrosis. Cathepsin G (CAT), a pro
Externí odkaz:
https://doaj.org/article/4d22b3a9b19c4f7fa5c46bb10e42b61f
Akademický článek
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Akademický článek
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