Zobrazeno 1 - 10
of 404
pro vyhledávání: '"Metal ion homeostasis"'
Autor:
Lihua Xu, Mingzheng Peng, Tingting Gao, Dandan Wang, Xiaowu Lian, Huihui Sun, Jinjin Shi, Yafeng Wang, Pengju Wang
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Endogenous essential metal ions play an important role in many life processes, especially in tumor development and immune response. The approval of various metallodrugs for tumor therapy brings more attention to the antitumor effect of metal
Externí odkaz:
https://doaj.org/article/bff8755ba3db450cb2b135c9539f7cce
Publikováno v:
Journal of Oral Microbiology, Vol 15, Iss 1 (2023)
ABSTRACTCandida albicans is a normal resident of the human oral cavity. It is also the most common fungal pathogen, causing various oral diseases, particularly in immunocompromised individuals. Chlorhexidine digluconate (CHG) is a broad-spectrum anti
Externí odkaz:
https://doaj.org/article/d34c09069f794d98b394accc6c396b2b
Akademický článek
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Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1466-1481 (2020)
With the rapid increase in the frequency of azole-resistant species, combination therapy appears to be a promising tool to augment the antifungal activity of azole drugs against resistant Candida species. Here, we report the effect of aprepitant, an
Externí odkaz:
https://doaj.org/article/45a4196d185a46b78c360bf6857c3d82
Autor:
Annie Ouyang, Kendall M. Gasner, Stephanie L. Neville, Christopher A. McDevitt, Elaine R. Frawley
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The divalent transition metal cation manganese is important for protein function, particularly under conditions of iron limitation, nitrosative stress, and oxidative stress, but can mediate substantial toxicity in excess. Salmonella enterica
Externí odkaz:
https://doaj.org/article/8dc3890db6fb480db9cce44d1bfe3b7a
Autor:
Nichaela Harbison-Price, Scott A. Ferguson, Adam Heikal, George Taiaroa, Kiel Hards, Yoshio Nakatani, David Rennison, Margaret A. Brimble, Ibrahim M. El-Deeb, Lisa Bohlmann, Christopher A. McDevitt, Mark von Itzstein, Mark J. Walker, Gregory M. Cook
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Globally, more antimicrobials are used in food-producing animals than in humans, and the extensive use of medically important human antimicrobials poses a significant public health threat in the face of rising antimicrobial resistance (AMR).
Externí odkaz:
https://doaj.org/article/7ba6568165cb4f2489d265bf769ffb42
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Huang Huang, Songqing Lai, Bai-Quan Qiu, Hua-Xi Zou, An-Di He, Lijun Wang, Jichun Liu, Cheng-Wu Gong, Xue-liang Zhou, Ming-Ming Yuan
Publikováno v:
Bioengineered, Vol 12, Iss 2, Pp 9976-9990 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Stanford type A aortic dissection (TAAD) is one of the most dangerous vascular diseases worldwide, and the mechanisms of its development remain unclear. Further molecular pathology studies may contribute to a comprehensive understanding of TAAD and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d8f35e2ab0ce6b1135eacbdbc3b1e9
https://doaj.org/article/12c2720191b546baa4a2e82ee0e9e4f0
https://doaj.org/article/12c2720191b546baa4a2e82ee0e9e4f0
Autor:
Amy M. Smith, Paul M. Matthews, David R. Owen, Maria Weinert, Robert C. J. Muirhead, Aisling McGarry, Karen Davey, Steve M. Gentleman, Combiz Khozoie, Eirini Liaptsi, Stergios Tsartsalis, Nurun Fancy, See Swee Tang
Publikováno v:
Acta Neuropathologica
Acta neuropathologica (2021)
Acta neuropathologica (2021)
To better define roles that astrocytes and microglia play in Alzheimer’s disease (AD), we used single-nuclei RNA-sequencing to comprehensively characterise transcriptomes in astrocyte and microglia nuclei selectively enriched during isolation post-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4234ec640db328ad17e0c53a54dfbc
https://doi.org/10.1007/s00401-021-02372-6
https://doi.org/10.1007/s00401-021-02372-6
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1466-1481 (2020)
Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications
Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications
With the rapid increase in the frequency of azole-resistant species, combination therapy appears to be a promising tool to augment the antifungal activity of azole drugs against resistant Candida species. Here, we report the effect of aprepitant, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9d6056141861255f622158bff873f3
https://doaj.org/article/45a4196d185a46b78c360bf6857c3d82
https://doaj.org/article/45a4196d185a46b78c360bf6857c3d82