Zobrazeno 1 - 10
of 706
pro vyhledávání: '"Metabotropic glutamate receptor 8"'
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 2, p 26 (2024)
Background: Microglia-mediated neuroinflammation is a hallmark of neurodegeneration. Metabotropic glutamate receptor 8 (GRM8) has been reported to promote neuronal survival in neurodegenerative diseases, yet the effect of GRM8 on neuroinflammation is
Externí odkaz:
https://doaj.org/article/58a54cb4e57a4bd6b12f119671c6fa44
Publikováno v:
Asian Spine Journal, Vol 15, Iss 2, Pp 200-206 (2021)
Study Design In this study, we decided to change the activity of periaqueductal gray (PAG)'s metabotropic glutamate receptors subtype 8 (mGluR8) by means of its specific agonist, (S)-3,4-dicarboxyphenylglycine (DCPG), and by knock downing it with mGl
Externí odkaz:
https://doaj.org/article/5ac04aa5aae24a7f8e3be099a31b18a4
Akademický článek
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Publikováno v:
Asian Spine Journal, Vol 15, Iss 2, Pp 200-206 (2021)
Asian Spine Journal
Asian Spine Journal
Study Design: In this study, we decided to change the activity of periaqueductal gray (PAG)'s metabotropic glutamate receptors subtype 8 (mGluR8) by means of its specific agonist, (S)-3,4-dicarboxyphenylglycine (DCPG), and by knock downing it with mG
Publikováno v:
Behavioural Pharmacology. 29:13-27
Treatments for the positive and negative symptoms of schizophrenia have been explored for decades, but no completely successful therapy has been found as yet. Metabotropic glutamate receptor 5 (mGluR5), which potentiates N-methyl-D-aspartate receptor
Publikováno v:
Neuroscience and Behavioral Physiology. 47:923-929
This review summarizes data on the interaction of effects arising as a result of activation of receptors for the main neurotransmitters in the CNS – glutamate and GABA. Reports on the structures and functions of the receptors for these signal subst
Publikováno v:
Neuroscience & Biobehavioral Reviews. 77:14-31
Emerging evidence indicates that dysfunctional glutamate neurotransmission is critical in the initiation and development of alcohol and drug dependence. Alcohol consumption induced downregulation of glutamate transporter 1 (GLT-1) as reported in prev
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
2-Arachidonoylglycerol and anandamide are the main endocannabinoids, which act through cannabinoid type-1 and type-2 receptors. Among its many functions, anandamide modulates anxiety-like behaviors in the ventromedial prefrontal cortex. The role of 2
Autor:
Amine Bahi
Publikováno v:
Pharmacology Biochemistry and Behavior. 155:32-42
Metabotropic glutamate receptors (mGluRs) are important modulators of excitatory neurotransmission, and have been implicated in addiction to alcohol and anxiety-related behaviors. However, the behavioral consequence and contribution of individual sub
Publikováno v:
Bulletin of Experimental Biology and Medicine. 162:784-787
Microinjection of kainic acid into rat hippocampus causes excitotoxic neuronal damage predominantly in the CA3 and CA1 fields. These lesions can be significantly reduced by simultaneous administration of MPEP, a negative allosteric modulator of type