Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Metabotropic glutamate receptor 4 (mGlu4 receptor)"'
Autor:
Anna Stankiewicz, Katarzyna Kaczorowska, Ryszard Bugno, Aneta Kozioł, Maria H. Paluchowska, Grzegorz Burnat, Barbara Chruścicka, Paulina Chorobik, Piotr Brański, Joanna M. Wierońska, Beata Duszyńska, Andrzej Pilc, Andrzej J. Bojarski
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 211-225 (2022)
Considering the allosteric regulation of mGlu receptors for potential therapeutic applications, we developed a group of 1,2,4-oxadiazole derivatives that displayed mGlu4 receptor positive allosteric modulatory activity (EC50 = 282–656 nM). Selectiv
Externí odkaz:
https://doaj.org/article/986c7044b75f497b83b535e2846fde7c
Autor:
Anna, Stankiewicz, Katarzyna, Kaczorowska, Ryszard, Bugno, Aneta, Kozioł, Maria H, Paluchowska, Grzegorz, Burnat, Barbara, Chruścicka, Paulina, Chorobik, Piotr, Brański, Joanna M, Wierońska, Beata, Duszyńska, Andrzej, Pilc, Andrzej J, Bojarski
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Considering the allosteric regulation of mGlu receptors for potential therapeutic applications, we developed a group of 1,2,4-oxadiazole derivatives that displayed mGlu4 receptor positive allosteric modulatory activity (EC50 = 282–656 nM). Selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::027706e7f575b861917c4d10a420e894
https://pubmed.ncbi.nlm.nih.gov/34894953
https://pubmed.ncbi.nlm.nih.gov/34894953
Autor:
Anna Stankiewicz, Katarzyna Kaczorowska, Ryszard Bugno, Aneta Kozioł, Maria H. Paluchowska, Grzegorz Burnat, Barbara Chruścicka, Paulina Chorobik, Piotr Brański, Joanna M. Wierońska, Beata Duszyńska, Andrzej Pilc, Andrzej J. Bojarski
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 211-225 (2022)
Considering the allosteric regulation of mGlu receptors for potential therapeutic applications, we developed a group of 1,2,4-oxadiazole derivatives that displayed mGlu4 receptor positive allosteric modulatory activity (EC50 = 282–656 nM). Selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e0e789aefc414044bfb30ca3c6530e
Publikováno v:
Expert Opinion on Drug Discovery. 13:411-423
Until recently, metabotropic glutamate receptor 4 (mGlu4) has not received adequate attention in terms of drug targeting when compared to other members of the same mGlu receptor family, possibly because of the difficulties encountered in developing h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad32c3467c608e464b4592b2c77e35d
https://doi.org/10.1080/17460441.2018.1443076
https://doi.org/10.1080/17460441.2018.1443076
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Akademický článek
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