An anomalous abundance of tryptophan residues in ceramide synthases based on analysis of all membrane proteins in the Swiss-Prot database.

Autor: Mestre B; Departments of Biomolecular Sciences and Weizmann Institute of Science, Rehovot 7610001, Israel., Zelnik ID; Departments of Biomolecular Sciences and Weizmann Institute of Science, Rehovot 7610001, Israel., Izrailov S; Departments of Biomolecular Sciences and Weizmann Institute of Science, Rehovot 7610001, Israel., Dingjan T; Departments of Biomolecular Sciences and Weizmann Institute of Science, Rehovot 7610001, Israel., Lvovsky G; Departments of Biomolecular Sciences and Weizmann Institute of Science, Rehovot 7610001, Israel., Fidel L; Departments ofLife Sciences Core Facilities, Weizmann Institute of Science, Rehovot 7610001, Israel., Ben-Dor S; Departments ofLife Sciences Core Facilities, Weizmann Institute of Science, Rehovot 7610001, Israel., Futerman AH; Departments of Biomolecular Sciences and Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: tony.futerman@weizmann.ac.il.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Dec 07, pp. 108053. Date of Electronic Publication: 2024 Dec 07.

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Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases.

Autor: Zelnik ID; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel., Mestre B; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel., Weinstein JJ; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel., Dingjan T; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel., Izrailov S; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel., Ben-Dor S; Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, 76100, Israel., Fleishman SJ; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel., Futerman AH; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel. tony.futerman@weizmann.ac.il.

Publikováno v: Nature communications [Nat Commun] 2023 Apr 22; Vol. 14 (1), pp. 2330. Date of Electronic Publication: 2023 Apr 22.

Preclinical evaluation of new radioligand of cholecystokinin/gastrin receptors in endocrine tumors xenograft nude mice

Autor: Brillouet, S., Caselles, O., Dierickx, L.O., Mestre, B., Nalis, J., Picard, C., Favre, G., Poirot, M., Silvente-Poirot, S., Courbon, F.

Publikováno v: In Nuclear Inst. and Methods in Physics Research, A 2007 571(1):160-164

Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs.

Autor: Becker-Gotot J; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany., Meissner M; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany., Kotov V; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany., Jurado-Mestre B; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany., Maione A; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia., Pannek A; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia., Albert T; Institute for Experimental Hematology and Transfusion Medicine (IHT), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany., Flores C; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany., Schildberg FA; Clinic for Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany., Gleeson PA; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia., Reipert BM; IMC University of Applied Sciences Krems, Krems, Austria., Oldenburg J; Institute for Experimental Hematology and Transfusion Medicine (IHT), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany., Kurts C; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2022 Nov 15; Vol. 132 (22). Date of Electronic Publication: 2022 Nov 15.