Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Mest Hj"'
Autor:
Alberto Corsini, Remo Fumagalli, Stefano Bellosta, Beitz J, Rodolfo Paoletti, P Grignaffini, Mest Hj
Publikováno v:
Cytotechnology. 11(Suppl 1)
The effect of trapidil derivative AR12456 on intracellular cholesterol metabolism was investigated in human hepatoma cell line HepG2. AR12456 enhanced the uptake and degradation of(125)I-LDL in a dose-dependent manner. The drug inhibited cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150d0ea4c5486d4c66b3f41fa9e72447
https://pubmed.ncbi.nlm.nih.gov/22358683
https://pubmed.ncbi.nlm.nih.gov/22358683
Publikováno v:
Pharmacological Research. 25:173-180
Different mediators released by anaphylaxis seem to be involved in different pathophysological conditions, including cardiac arrhythmia. Histamine, 5-HT and platelet-activating factor (PAF) could participate in the enhanced arrhythmogenicity during a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21179db3c964076da38c8000bad688da
https://doi.org/10.1016/1043-6618(92)91385-t
https://doi.org/10.1016/1043-6618(92)91385-t
Publikováno v:
Pharmacological Research. 22:445-453
The hetrazepine derivative WEB 2086 (0.5-2 mg/kg, i.v.), a well known PAF receptor antagonist, was found to reduce the arrhythmogenic effect of PAF in a dose dependent manner on ouabain induced arrhythmias in guinea-pigs. There was no detectable subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c01a861aa83354d1ede68564b8ab64f
https://doi.org/10.1016/1043-6618(90)90751-x
https://doi.org/10.1016/1043-6618(90)90751-x
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 48(6)
The study was performed to investigate the influence of lipoproteins (LP) on the thromboxane (TX) A2 formation capacity of platelets in clotting whole blood in vitro. The different lipoprotein fractions VLDL, LDL, HDL2 and HDL3 were isolated from blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd89dd712f40b01fa35b93395fdfff4
https://pubmed.ncbi.nlm.nih.gov/8341726
https://pubmed.ncbi.nlm.nih.gov/8341726
Publikováno v:
Prostaglandins in the Cardiovascular System ISBN: 9783034872645
The threshold dose of ouabain necessary to induce ventricular fibrillation is decreased in sensitized guinea-pigs signalizing an enhanced arrhythmogenicity. Esculetine or WEB 2170 antagonists of histamine and PAF, respectively and especially a combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dacd13dc40bbfbb1536623469678627a
https://doi.org/10.1007/978-3-0348-7262-1_32
https://doi.org/10.1007/978-3-0348-7262-1_32
Publikováno v:
Prostaglandins in the Cardiovascular System ISBN: 9783034872645
In the study was investigated whether the formation of prostanoids is changed in the different regions of aorta or in clotting whole blood in dependence on development of atherosclerosis. For this question New Zealand rabbits were fed for different p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02e5974d83daea6a67212bd7b686b669
https://doi.org/10.1007/978-3-0348-7262-1_33
https://doi.org/10.1007/978-3-0348-7262-1_33
Autor:
Alberto Corsini, Stefano Bellosta, Mest Hj, F. Bernini, Rodolfo Paoletti, Remo Fumagalli, Beitz J
Publikováno v:
Pharmacological research. 24(3)
The effect of trapidil (Rocornal) and its derivatives AR 12456 and AR 12463 on endogenous cholesterol synthesis and on cholesterol esterification rate was studied in human skin fibroblasts (HSF), in human hepatoma cell line Hep G2 and in primary cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da63df9469e3d8c09a38a2ffd1babbd3
https://pubmed.ncbi.nlm.nih.gov/1956868
https://pubmed.ncbi.nlm.nih.gov/1956868
Autor:
Mest Hj, Beitz J, Rodolfo Paoletti, R. Fumagalli, Alberto Corsini, F. Bernini, Stefano Bellosta
Publikováno v:
Atherosclerosis and Cardiovascular Disease ISBN: 9789401068147
The effect of trapidil (RocornalR) and some of its newly developed derivatives on the receptor-mediated low density lipoprotein (LDL) uptake and degradation was studied in human skin fibroblasts (HSF) and human hepatoma cell line Hep G2. One compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f8a55907d8a80370778328f0f1b190
https://doi.org/10.1007/978-94-009-0731-7_60
https://doi.org/10.1007/978-94-009-0731-7_60
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