RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity.

Autor: Orozco SL; Department of Immunology, University of Washington, Seattle, WA 98109, USA; Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98109, USA., Daniels BP; Department of Immunology, University of Washington, Seattle, WA 98109, USA., Yatim N; Department of Immunology, Pasteur Institute, 75724 Paris, France., Messmer MN; Department of Immunology, University of Washington, Seattle, WA 98109, USA., Quarato G; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Chen-Harris H; Department of Cancer Immunology, Genentech, Inc., South San Francisco, CA 94080, USA., Cullen SP; Department of Cancer Immunology, Genentech, Inc., South San Francisco, CA 94080, USA., Snyder AG; Department of Immunology, University of Washington, Seattle, WA 98109, USA., Ralli-Jain P; Department of Immunology, University of Washington, Seattle, WA 98109, USA., Frase S; Cell and Tissue Imaging Center, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Tait SWG; Cancer Research UK Beatson Institute, Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1BD, UK., Green DR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Albert ML; Department of Cancer Immunology, Genentech, Inc., South San Francisco, CA 94080, USA., Oberst A; Department of Immunology, University of Washington, Seattle, WA 98109, USA. Electronic address: oberst@uw.edu.

Publikováno v: Cell reports [Cell Rep] 2019 Aug 27; Vol. 28 (9), pp. 2275-2287.e5.

Comparing the effects of different cell death programs in tumor progression and immunotherapy.

Autor: Messmer MN; Department of Immunology, University of Washington, Seattle, WA, 98109, USA., Snyder AG; Department of Immunology, University of Washington, Seattle, WA, 98109, USA., Oberst A; Department of Immunology, University of Washington, Seattle, WA, 98109, USA. Oberst@uw.edu.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2019 Jan; Vol. 26 (1), pp. 115-129. Date of Electronic Publication: 2018 Oct 19.

HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting cells.

Autor: Kinner-Bibeau LB; Department of Immunology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, Pennsylvania 15261, USA., Sedlacek AL; Department of Immunology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, Pennsylvania 15261, USA., Messmer MN; Department of Immunology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York 14263, USA., Watkins SC; Department of Cell Biology, University of Pittsburgh, 200 Lothrop Street, Pennsylvania 15261, USA., Binder RJ; Department of Immunology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, Pennsylvania 15261, USA.

Publikováno v: Nature communications [Nat Commun] 2017 May 31; Vol. 8, pp. 15648. Date of Electronic Publication: 2017 May 31.

Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes.

Autor: Ku AW; Department of Immunology, Roswell Park Cancer Institute, Buffalo, United States., Muhitch JB; Department of Immunology, Roswell Park Cancer Institute, Buffalo, United States.; Department of Urology, Roswell Park Cancer Institute, Buffalo, United States., Powers CA; Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, United States., Diehl M; Department of Immunology, Roswell Park Cancer Institute, Buffalo, United States., Kim M; Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, United States., Fisher DT; Department of Immunology, Roswell Park Cancer Institute, Buffalo, United States.; Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, United States., Sharda AP; Department of Urology, Roswell Park Cancer Institute, Buffalo, United States., Clements VK; Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, United States., O'Loughlin K; Flow and Image Cytometry, Roswell Park Cancer Institute, Buffalo, United States., Minderman H; Flow and Image Cytometry, Roswell Park Cancer Institute, Buffalo, United States., Messmer MN; Department of Immunology, Roswell Park Cancer Institute, Buffalo, United States., Ma J; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, United States., Skitzki JJ; Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, United States., Steeber DA; Department of Biological Sciences, University of Wisconsin-Milwaukee, Milwaukee, United States., Walcheck B; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, United States., Ostrand-Rosenberg S; Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, United States., Abrams SI; Department of Immunology, Roswell Park Cancer Institute, Buffalo, United States., Evans SS; Department of Immunology, Roswell Park Cancer Institute, Buffalo, United States.

Publikováno v: ELife [Elife] 2016 Dec 08; Vol. 5. Date of Electronic Publication: 2016 Dec 08.

Tumor-induced myeloid dysfunction and its implications for cancer immunotherapy.

Autor: Messmer MN; Department of Immunology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, 14263, USA., Netherby CS, Banik D, Abrams SI

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2015 Jan; Vol. 64 (1), pp. 1-13. Date of Electronic Publication: 2014 Nov 29.