Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mesias Pedroza"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cadherin-11 (CDH11) is a cell-cell adhesion protein that has previously been reported to play an important role in the pathogenesis of pulmonary fibrosis. It is expressed on macrophages in the fibrotic lung. However, the role of CDH11 on macrophage b
Externí odkaz:
https://doaj.org/article/74dfa42f610940f8be6fe09081d63b67
Autor:
Scott D. Collum, Jose G. Molina, Ankit Hanmandlu, Weizhen Bi, Mesias Pedroza, Tinne C. J. Mertens, Nancy Wareing, Wang Wei, Cory Wilson, Wenchao Sun, Jayakumar Rajadas, Paul L. Bollyky, Kemly M. Philip, Dewei Ren, Rajarajan A. Thandavarayan, Brian A. Bruckner, Yang Xia, Michael R. Blackburn, Harry Karmouty-Quintana
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 5 (2019)
Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 years. Pulmonary hypertension (PH) is a frequently fatal complication o
Externí odkaz:
https://doaj.org/article/f39f176cadcb47ad8f440b3c7ff70dd8
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218971 (2019)
Background and aimsLiver fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) leading to impaired function and cirrhosis. Previous reports support a role for cadherin-11 (CDH11) in regulating the development of dermal a
Externí odkaz:
https://doaj.org/article/21a6c55c0adb4f3b88694e5e85b0dbe9
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187109 (2017)
Systemic sclerosis (SSc) is an autoimmune disease clinically manifesting as progressive fibrosis of the skin and internal organs. Cadherin-11 (CDH11) expression is increased in fibrotic skin and lung tissue. Targeting CDH11 may be an effective approa
Externí odkaz:
https://doaj.org/article/1300dda624c743bb94fa574dfeea3859
Autor:
Mesias Pedroza, Daniel J Schneider, Harry Karmouty-Quintana, Julie Coote, Stevan Shaw, Rebecca Corrigan, Jose G Molina, Joseph L Alcorn, David Galas, Richard Gelinas, Michael R Blackburn
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22667 (2011)
BackgroundChronic lung diseases are the third leading cause of death in the United States due in part to an incomplete understanding of pathways that govern the progressive tissue remodeling that occurs in these disorders. Adenosine is elevated in th
Externí odkaz:
https://doaj.org/article/55b1329ceccf4e169ad2b50505e6c82d
Autor:
Michael R. Blackburn, Yang Xia, Wang Wei, Cory Wilson, Mesias Pedroza, Tinne C.J. Mertens, Jose G. Molina, Nancy Wareing, Scott D. Collum, Jayakumar Rajadas, Dewei Ren, Wenchao Sun, Ankit Hanmandlu, Harry Karmouty-Quintana, Rajarajan Amirthalingam Thandavarayan, Kemly Philip, Brian A. Bruckner, Paul L. Bollyky, Weizhen Bi
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 5 (2019)
Disease Models & Mechanisms
Disease Models & Mechanisms
Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 years. Pulmonary hypertension (PH) is a frequently fatal complication o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc27f60716a393dfa0f784d355dd188
http://dmm.biologists.org/content/12/5/dmm038711
http://dmm.biologists.org/content/12/5/dmm038711
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218971 (2019)
PLoS ONE
PLoS ONE
Background and aimsLiver fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) leading to impaired function and cirrhosis. Previous reports support a role for cadherin-11 (CDH11) in regulating the development of dermal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247e3196a1f4c3870ba96c5e3e654393
https://doaj.org/article/21a6c55c0adb4f3b88694e5e85b0dbe9
https://doaj.org/article/21a6c55c0adb4f3b88694e5e85b0dbe9
Objective SSc is an autoimmune disease characterized by progressive fibrosis of the skin and internal organs. IL-6 and related cytokines that signal through STAT3 have been implicated in the pathogenesis of SSc and mouse models of fibrosis. The aim o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74549914d3da4a9f3fe9c1da0fe0679
https://europepmc.org/articles/PMC6152423/
https://europepmc.org/articles/PMC6152423/
Autor:
Minghua Wu, Robert Lafyatis, Sandeep K. Agarwal, Filemon K. Tan, Mesias Pedroza, Shervin Assassi, Michael B. Brenner, Anuh T. George, Maureen D. Mayes
Publikováno v:
Arthritis & Rheumatology. 66:1010-1021
Objective Systemic sclerosis (SSc) is a chronic autoimmune disease clinically manifesting as progressive fibrosis of the skin and internal organs. Recent microarray studies demonstrated that cadherin 11 (Cad-11) expression is increased in the affecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d3771026d964cfb9f3ca71a68a25c0
https://doi.org/10.1002/art.38275
https://doi.org/10.1002/art.38275
Autor:
Mesias Pedroza, Sharon Rounds, Julie Newton, Sean Curren, Michael R. Blackburn, Gustavo Andres Gabino Miranda, Vivian Hsiao, Paul Shamirian, Qing Lu, Pavlo Sakhatskyy
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 304:L361-L370
Pulmonary endothelial cell (EC) apoptosis has been implicated in the pathogenesis of emphysema. Cigarette smoke (CS) causes lung EC apoptosis and emphysema. In this study, we show that CS exposure increased lung tissue adenosine levels in mice, an ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37592c2ef4c80124bca55a53f9975ae8
https://doi.org/10.1152/ajplung.00161.2012
https://doi.org/10.1152/ajplung.00161.2012