Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Mesfin Gewe"'
Autor:
Zachary R. Crook, Gregory P. Sevilla, Della Friend, Mi-Youn Brusniak, Ashok D. Bandaranayake, Midori Clarke, Mesfin Gewe, Andrew J. Mhyre, David Baker, Roland K. Strong, Philip Bradley, James M. Olson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Pathologies related to protein:protein interaction are hard to treat but cystine-dense peptides have the potential to disrupt such interactions. Here the authors develop a high-diversity mammalian cell screen for cystine-dense peptides with drug pote
Externí odkaz:
https://doaj.org/article/68a2dc186894404db175693588126a0e
Autor:
Zachary R. Crook, Gregory P. Sevilla, Della Friend, Mi-Youn Brusniak, Ashok D. Bandaranayake, Midori Clarke, Mesfin Gewe, Andrew J. Mhyre, David Baker, Roland K. Strong, Philip Bradley, James M. Olson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original version of this Article the colour key for the amino acid enrichment score was inadvertently omitted from the lower panel of Figure 5b during the production process. This has now been corrected in the PDF and HTML versions of the Arti
Externí odkaz:
https://doaj.org/article/caef314988974c389dd59d59ca7db80e
Autor:
Kathryn A K Finton, Della Friend, James Jaffe, Mesfin Gewe, Margaret A Holmes, H Benjamin Larman, Andrew Stuart, Kevin Larimore, Philip D Greenberg, Stephen J Elledge, Leonidas Stamatatos, Roland K Strong
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004403 (2014)
The process of antibody ontogeny typically improves affinity, on-rate, and thermostability, narrows polyspecificity, and rigidifies the combining site to the conformer optimal for binding from the broader ensemble accessible to the precursor. However
Externí odkaz:
https://doaj.org/article/45f3e83ef2314dde8d33dae1238ab588
Autor:
Benjamin W. Jester, Hui Zhao, Mesfin Gewe, Thomas Adame, Lisa Perruzza, David T. Bolick, Jan Agosti, Nhi Khuong, Rolf Kuestner, Caitlin Gamble, Kendra Cruickshank, Jeremy Ferrara, Rachelle Lim, Troy Paddock, Colin Brady, Stacey Ertel, Miaohua Zhang, Alex Pollock, Jamie Lee, Jian Xiong, Michael Tasch, Tracy Saveria, David Doughty, Jacob Marshall, Damian Carrieri, Lauren Goetsch, Jason Dang, Nathaniel Sanjaya, David Fletcher, Anissa Martinez, Bryce Kadis, Kristjan Sigmar, Esha Afreen, Tammy Nguyen, Amanda Randolph, Alexandria Taber, Ashley Krzeszowski, Brittney Robinett, David B. Volkin, Fabio Grassi, Richard Guerrant, Ryo Takeuchi, Brian Finrow, Craig Behnke, James Roberts
Publikováno v:
Nature Biotechnology. 40:956-964
The use of the edible photosynthetic cyanobacterium Arthrospira platensis (spirulina) as a biomanufacturing platform has been limited by a lack of genetic tools. Here we report genetic engineering methods for stable, high-level expression of bioactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc72201487f5ff22957927d75b57374
https://doi.org/10.1038/s41587-022-01249-7
https://doi.org/10.1038/s41587-022-01249-7
Autor:
Hui Zhao, Michael Dodds, Michael Tasch, Mesfin Gewe, Anissa Martinez, Melanie Hutton, Kristie Keeney, Alex Pollock, Benjamin W. Jester, Nhi Khuong, Mia Zhang, Stacey Ertel, Colin Brady, Mark Heinnickel, Hannah Tabakh, Nathan Sanjaya, Kendra Cruickshank, Troy Paddock, Sarah Struyvenberg, Jason Dang, Tracy Saveria, Chelsea Shanitta, David Fletcher, Kristjan Sigmar, Lauren Goetsch, Caitlin Gamble, Steven J. Mileto, Ryan Heselpoth, Dena Lyras, Craig A. Behnke, Vincent Fischetti, Brian Finrow, James M. Roberts
Drugs which independently inhibit a shared target or pathway can have synthetic activities that result in multiplicative instead of merely additive potencies. This characteristic of drug combinations can be quantified by expressing the potency of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3acc58ac9dbf12a359540fab7049897
https://doi.org/10.1101/2021.12.21.473715
https://doi.org/10.1101/2021.12.21.473715
Autor:
Tracy Saveria, Brittney Robinett, Tammy Nguyen, Jacob Marshall, Ryo Takeuchi, Ashley Krzeszowski, James A. Roberts, Lisa Perruzza, Khuong Nhi, Mesfin Gewe, Bryce Kadis, Nathaniel Sanjaya, Rolf E. Kuestner, Stacey Ertel, Michael Tasch, Jan M. Agosti, Craig A. Behnke, Kendra Cruickshank, Hui Zhao, David Fletecher, Brian Finrow, Jeremy Ferrara, Mia Zhang, David M. Doughty, Michael Spigarelli, Colin Brady, Troy Paddock, Jason Dang, Thomas Adame, Fabio Grassi, Benjamin Jester, Kristjian Sigmar, Richard Guerrant, David T. Bolick, Alexandria Taber, Esha Afreen, Rachelle Lim, Lauren Goetsch, Caitlin Gamble, Damian Carrieri, Anissa Martinez, Amanda Randolph, Jamie Lee
Arthrospira platensis(commonly known as spirulina) is a photosynthetic cyanobacterium1. It is a highly nutritious food that has been consumed for decades in the US, and even longer by indigenous cultures2. Its widespread use as a safe food source and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc0b074c37ad012b3bc18e8a5f86c3dc
https://doi.org/10.1101/2021.01.25.427910
https://doi.org/10.1101/2021.01.25.427910
Autor:
Benjamin W. Jester, Hui Zhao, Mesfin Gewe, Thomas Adame, Lisa Perruzza, David T. Bolick, Jan Agosti, Nhi Khuong, Rolf Kuestner, Caitlin Gamble, Kendra Cruickshank, Jeremy Ferrara, Rachelle Lim, Troy Paddock, Colin Brady, Stacey Ertel, Miaohua Zhang, Alex Pollock, Jamie Lee, Jian Xiong, Michael Tasch, Tracy Saveria, David Doughty, Jacob Marshall, Damian Carrieri, Lauren Goetsch, Jason Dang, Nathaniel Sanjaya, David Fletcher, Anissa Martinez, Bryce Kadis, Kristjan Sigmar, Esha Afreen, Tammy Nguyen, Amanda Randolph, Alexandria Taber, Ashley Krzeszowski, Brittney Robinett, David B. Volkin, Fabio Grassi, Richard Guerrant, Ryo Takeuchi, Brian Finrow, Craig Behnke, James Roberts
Publikováno v:
Nature Biotechnology. 40:974-974
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08addfae947d08ba6435378d284c3e25
https://doi.org/10.1038/s41587-022-01323-0
https://doi.org/10.1038/s41587-022-01323-0
Autor:
Rüdiger Horstkorte, Bettina Büttner, Kaya Bork, Navdeep Sahota, Sarah Sabir, Laura O’Regan, Joelle Blot, Detina Zalli, Joanne Baxter, Giancarlo Barone, Andrew Fry, Jeffrey A. Frost, Tooru Mizuno, Rut Valdor, Brian T. Abe, Fernando Macian, Maria D. Sanchez-Niño, Ana B. Sanz, Maria C. Izquierdo, Jonay Poveda, Alberto Ortiz, Byong Kwon Yoo, C. Chris Yun, Bin Xu, Mesfin Gewe, Kathryn Finton, Roland K. Strong, Michael T. McCarthy, Christopher A. O’Callaghan, Simona Sivori, Sujeet Kumar, Ponniah Selvakumar, Jonathan R. Dimmock, Rajendra K. Sharma, Gibeom Park, Woong-Yang Park, Sang Geon Kim, Woo Hyung Lee, Young Woo Kim, Ping-Chih Ho, Li-Na Wei, Jian-Bing Shen, Bruce T. Liang, Florentina Soto, Didier Communi, Bernard Robaye, Jean Marie Boeynaems, Haein Park, Athanassios Dovas, Dianne Cox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96061b2b8373de571a0cd1048b281bc5
https://doi.org/10.1007/978-1-4419-0461-4_198
https://doi.org/10.1007/978-1-4419-0461-4_198
Autor:
Rüdiger Horstkorte, Bettina Büttner, Kaya Bork, Navdeep Sahota, Sarah Sabir, Laura O’Regan, Joelle Blot, Detina Zalli, Joanne Baxter, Giancarlo Barone, Andrew Fry, Jeffrey A. Frost, Tooru Mizuno, Rut Valdor, Brian T. Abe, Fernando Macian, Maria D. Sanchez-Niño, Ana B. Sanz, Maria C. Izquierdo, Jonay Poveda, Alberto Ortiz, Byong Kwon Yoo, C. Chris Yun, Bin Xu, Mesfin Gewe, Kathryn Finton, Roland K. Strong, Michael T. McCarthy, Christopher A. O’Callaghan, Simona Sivori, Sujeet Kumar, Ponniah Selvakumar, Jonathan R. Dimmock, Rajendra K. Sharma, Gibeom Park, Woong-Yang Park, Sang Geon Kim, Woo Hyung Lee, Young Woo Kim, Ping-Chih Ho, Li-Na Wei, Jian-Bing Shen, Bruce T. Liang, Florentina Soto, Didier Communi, Bernard Robaye, Jean Marie Boeynaems, Haein Park, Athanassios Dovas, Dianne Cox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23608b214a7baeb1a79fe409a13b9a01
https://doi.org/10.1007/978-1-4419-0461-4_393
https://doi.org/10.1007/978-1-4419-0461-4_393