Zobrazeno 1 - 10
of 393
pro vyhledávání: '"Mesenchymal stroma"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background The release of extracellular vesicles (EVs) including exosomes from human mesenchymal stroma/stem-like cells (MSC) represents valuable cell-free carriers for the delivery of regenerative and medicinal compounds. Methods EVs/exosom
Externí odkaz:
https://doaj.org/article/dfbb409c7111468a8a808b5b9590b525
Autor:
Sabrina Marozin, Birgit Simon-Nobbe, Astrid Huth, Evelyn Beyerer, Laurenz Weber, Andreas Nüssler, Günter Lepperdinger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Skeletal bone function relies on both cells and cellular niches, which, when combined, provide guiding cues for the control of differentiation and remodeling processes. Here, we propose an in vitro 3D model based on human fetal osteoblasts,
Externí odkaz:
https://doaj.org/article/f24dbf20c9bc412abb1cde9ddce2fa81
Akademický článek
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Akademický článek
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Autor:
Chengxin Luo, Xiangtao Huang, Ling Wei, Guixian Wu, Yarui Huang, Yaqun Ding, Zhen Huang, Jieping Chen, Xi Li, Yunding Zou, Shuangnian Xu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveSteroids-refractory (SR) acute graft-versus-host disease (aGVHD) is a life-threatening condition in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), but the optimal second-line therapy still has not been es
Externí odkaz:
https://doaj.org/article/e66f50146f0d4e6192233a60304994ac
Autor:
Brady Trevisan, Martin Rodriguez, Hailey Medder, Shannon Lankford, Rebecca Combs, John Owen, Anthony Atala, Christopher D. Porada, Graça Almeida-Porada
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionHemophilia A (HA) is the most common X-linked bleeding disorder, occurring in 1 in 5,000 live male births and affecting >1 million individuals worldwide. Although advances in protein-based HA therapeutics have improved health outcomes, cu
Externí odkaz:
https://doaj.org/article/59c44bce82bc4c60bc3be1f87a9f1c9f
Autor:
Jessica Ceccato, Maria Piazza, Marco Pizzi, Sabrina Manni, Francesco Piazza, Ilaria Caputo, Francesco Cinetto, Lorena Pisoni, Diletta Trojan, Riccardo Scarpa, Renato Zambello, Angelo Paolo Dei Tos, Livio Trentin, Gianpietro Semenzato, Fabrizio Vianello
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
About 30% of patients with diffuse large B-cell lymphoma (DLBCL) relapse or exhibit refractory disease (r/r DLBCL) after first-line immunochemotherapy. Bone marrow (BM) involvement confers a dismal prognosis at diagnosis, likely due to the interactio
Externí odkaz:
https://doaj.org/article/0e0dafcd81a545ca8ab648bf6c1bc02e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Skeletal stem/progenitor cells (SSPCs) are critical for fracture repair by providing osteo-chondro precursors in the callus, which is impaired in aging. However, the molecular signatures of callus SSPCs during aging are not known. Herein, we performe
Externí odkaz:
https://doaj.org/article/ba9788c7d1f44ad89495d3062a8ddd40
Autor:
Athanasia Warnecke, Jennifer Harre, Matthew Shew, Adam J. Mellott, Igor Majewski, Martin Durisin, Hinrich Staecker
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Mesenchymal stromal cells (MSCs) are an adult derived stem cell-like population that has been shown to mediate repair in a wide range of degenerative disorders. The protective effects of MSCs are mainly mediated by the release of growth factors and c
Externí odkaz:
https://doaj.org/article/1ddf6581bee346c9ab38d1bcadb3854f
Autor:
Alice Pievani, Roberto Savoldelli, Juliane Poelchen, Elisa Mattioli, Giorgio Anselmi, Alice Girardot, Jochen Utikal, Pierre Bourdely, Marta Serafini, Pierre Guermonprez
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tissue engineering opens multiple opportunities in regenerative medicine, drug testing, and modeling of the hematopoiesis in health and disease. Recapitulating the organization of physiological microenvironments supporting leukocyte development is es
Externí odkaz:
https://doaj.org/article/0f513972e2044522bea853a714f9d80a