Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Mesangial matrix"'
Autor:
Marina López-Martínez, Maria Pilar Armengol, Irina Pey, Xavier Farré, Paula Rodríguez-Martínez, Mireia Ferrer, Esteban Porrini, Sergio Luis-Lima, Laura Díaz-Martín, Ana Elena Rodríguez-Rodríguez, Coriolano Cruz-Perera, Marta Alcalde, Maruja Navarro-Díaz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6437 (2024)
This study aimed to investigate obesity-related glomerulopathy (ORG) at cellular, structural, and transcriptomic levels. Thirty Wistar rats were randomized into two groups: 15 rats were fed with a standard diet (SD-rats), and 15 rats were fed with a
Externí odkaz:
https://doaj.org/article/7542db3638e34a9fbfee2acc4ee35c51
Publikováno v:
Journal of Biological Engineering, Vol 16, Iss 1, Pp 1-13 (2022)
Abstract Diabetic nephropathy, a kidney complication arising from diabetes, is the leading cause of death in diabetic patients. Unabated, the growing epidemic of diabetes is increasing instances of diabetic nephropathy. Although the main causes of di
Externí odkaz:
https://doaj.org/article/a5f46ffc095a4369a7467ff9accf56e2
Akademický článek
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Autor:
Elisabet Van Loon, Joseph Pierre Aboumsallem, Evelyne Lerut, Marija Bogojevic, Aleksandar Denic, Walter Park, Ilayaraja Muthuramu, Mudit Mishra, Mark Stegall, Maarten Naesens, Bart De Geest
Publikováno v:
Journal of Nephropathology, Vol 10, Iss 2, Pp e17-e17 (2021)
Introduction: The evolution of structural changes of diabetic nephropathy in human kidneys is not well documented. Instead, rodent models are used to study diabetic nephropathy in greater detail. However, all rodent models to date are subject to impo
Externí odkaz:
https://doaj.org/article/fd2f6e616b404819be95e91e52d7c41a
Akademický článek
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Autor:
Hermann-Josef Gröne, Jana Löwen, Felix Bestvater, Wilhelm Kriz, Marie-Luise Groß-Weißmann, Elisabeth F. Gröne
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F600-F616
Based on analysis of 819 human biopsies, essential derangement in diabetic nephropathy consists of accumulation of worn-out glomerular basement membrane in the mesangium that may advance to global sclerosis. The most frequent pathway to nephron dropo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2fb854a0ad4739863393613ebce7c6
https://doi.org/10.1152/ajprenal.00669.2020
https://doi.org/10.1152/ajprenal.00669.2020
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5349 (2019)
The alteration of mesangial matrix (MM) components in mesangium, such as type IV collagen (COL4) and type I collagen (COL1), is commonly found in progressive glomerular disease. Mesangial cells (MCs) responding to altered MM, show critical changes in
Externí odkaz:
https://doaj.org/article/7830c0f4ffb9403ea8f782bb088e118d
Akademický článek
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Autor:
Deepa Taneja, Joel Thompson, Patricia Wilson, Katie Brandewie, Liliana Schaefer, Bonnie Mitchell, Lisa R. Tannock
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1464-1470 (2010)
Hyperlipidemia is a risk factor for development and progression of diabetic nephropathy. However, it is not known if reduction of hyperlipidemia is protective against progression of disease. The goal of this study was to determine if reduction of hyp
Externí odkaz:
https://doaj.org/article/1d5df666c4b449e38c56672119d08ed5
Autor:
Guillermo A. Herrera
Publikováno v:
Ultrastructural pathology. 45(4-5)
For many years amyloidosis was considered an extremely rare, somewhat mysterious disease. However, in the last 2-3 decades its pathogenesis, particularly that of renal amyloidosis has been carefully dissected in the research laboratory using in-vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57da7d5ac3bb452e3d32a95928f2e0a8
https://pubmed.ncbi.nlm.nih.gov/34482805
https://pubmed.ncbi.nlm.nih.gov/34482805