Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Meryl K, Brune"'
Autor:
Mieke Hoock, Catrina Fronick, Gue Su Chang, Angela M. Verdoni, David H. Spencer, Elizabeth R. Leight, Robert S. Fulton, Celia V. Bangert, Christopher A. Miller, Meryl K. Brune, Nichole M. Helton, Timothy J. Ley, Amanda Smith, Daniel R. George, David Y. Chen, Sai Mukund Ramakrishnan, Shamika Ketkar, Allegra A. Petti
Publikováno v:
Proceedings of the National Academy of Sciences. 117:3123-3134
Mutations in the DNA methyltransferase 3A ( DNMT3A ) gene are the most common cause of age-related clonal hematopoiesis (ARCH) in older individuals, and are among the most common initiating events for acute myeloid leukemia (AML). The most frequent D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a73828fa5a10b09980e27c95b12a85a7
https://doi.org/10.1073/pnas.1918611117
https://doi.org/10.1073/pnas.1918611117
Autor:
Shamika, Ketkar, Angela M, Verdoni, Amanda M, Smith, Celia V, Bangert, Elizabeth R, Leight, David Y, Chen, Meryl K, Brune, Nichole M, Helton, Mieke, Hoock, Daniel R, George, Catrina, Fronick, Robert S, Fulton, Sai Mukund, Ramakrishnan, Gue Su, Chang, Allegra A, Petti, David H, Spencer, Christopher A, Miller, Timothy J, Ley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Mutations that reduce the function of the de novo DNA methyltransferase, DNMT3A, are very common in patients with clonal hematopoiesis and hematopoietic malignancies. Restoring the function of DNMT3A in mouse hematopoietic cells deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5880c8fc6f1e2d090f24ad74042b015
https://pubmed.ncbi.nlm.nih.gov/31996479
https://pubmed.ncbi.nlm.nih.gov/31996479