Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Meryl H. Karol"'
Autor:
Meryl H. Karol
Publikováno v:
Biomolecules and Therapeutics. 17:113-124
- Aging is a multifaceted biological process that affects all organs and organ systems of the body. This review provides an up-to-date analysis of this highly exciting, rapidly changing field of science. The aging process is largely under genetic c
Publikováno v:
Environmental Science & Technology. 41:4861-4867
Increasingly, airborne mold in home environments has been linked with asthma exacerbation and other respiratory diseases in both children and adults. This problem is particularly relevanttoday, as Hurricane Katrina has resulted in water damage and mo
Publikováno v:
Environmental Health Perspectives
Background People in modern societies spend more than 90% of their time indoors. Hence, indoor environmental quality (IEQ) has a significant impact on public health. In this article we describe health risks associated with indoor environments, illumi
Autor:
Meryl H. Karol
Publikováno v:
Toxicology. :305-310
The prevalence of asthma is increasing worldwide. The increase has been found for both sexes, for all races and age groups. The factors responsible are unclear. The short period of increase makes it unlikely that a genetic change is responsible but r
Publikováno v:
Clinical & Experimental Allergy. 31:1067-1076
Background Nearly 9 million individuals are exposed to agents in the workplace associated with asthma, and isocyanates represent the most common cause of occupationally induced asthma. Objectives Nonetheless, the immunological mechanisms responsible
Autor:
Koichi Ebino, Yasufumi Shutoh, Eiko Nagayoshi, Meryl H. Karol, Hideo Ueda, Hisao Kawakatsu, Tadashi Kosaka, Ranulfo Lemus
Publikováno v:
Toxicology Letters. 121:79-85
Toluene diisocyanate (TDI), a highly reactive industrial chemical is a leading cause of occupational asthma in westernized countries. It has also been reported to be a skin sensitizer in mice and guinea pigs although instances of skin sensitivity in
Autor:
Meryl H. Karol
Publikováno v:
Clinical & Experimental Allergy. 31:357-360
Autor:
Meryl H. Karol, Carole Holm, Joyce S. Chung, Mark R. Cullen, Rebecca Gore, James Appiah-Pippim, Susan Woskie, Youcheng Liu, Adam V. Wisnewski, Meredith H. Stowe, Judy Sparer, Ranulfo Lemus, Carrie A. Redlich, Ellen A. Eisen
Publikováno v:
American Journal of Industrial Medicine. 39:587-597
Background Diisocyanates are potent sensitizing agents and currently the most commonly identified cause of occupational asthma in industrialized countries. However, diisocyanate asthma is difficult to diagnose and exposure and host risk factors are u
Publikováno v:
Quantitative Structure-Activity Relationships. 19:467-474
SAR model development should be a continuous process involving formulation then experimental testing of the model, incorporation of test results into the database, then refinement of the model using the expanded database. The larger database affords
Autor:
Ranjana Srivastava, Adam V. Wisnewski, Kim Bottomly, Christina Herick, Meryl H. Karol, Hilary Cain, Nadine Magoski, Ranulfo Lemus, Carrie A. Redlich, Lan Xu
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 162:2330-2336
Diisocyanates are asthma-causing chemicals used in the commercial production of polyurethane. We have previously shown that human lung epithelial cell proteins can become conjugated with hexamethylene diisocyanate (HDI) and may be biologically import