Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Meryem Alagoz"'
Publikováno v:
Sakarya Tıp Dergisi, Vol 9, Iss 4, Pp 715-720 (2019)
ÖzetAmaç: Mental retardasyon genetik ve çevresel faktörlerin etkilileri sonucu ortaya çıkan konjenital anomalilerdir. Genetik bozuklukların Mental retardasyonun gelişmesindeki etkinliği göz önüne alındığında genetik tanın hastalığ
Externí odkaz:
https://doaj.org/article/ef75c54fd09142f8bfc919e2dc562129
Glioblastoma Multiforma Tedavisinde Kanser Kök Hücrelerinin Temozolomide Karşı Oluşturdukları Direnç
Autor:
Meryem Alagoz
Publikováno v:
Sakarya Tıp Dergisi, Vol 8, Iss 2, Pp 379-387 (2018)
Glioblastoma multiform (GBM), primer beyin tümörleri arasında en sık görülen agresif bir malign kanser türüdür. Tümörün cerrahi rezeksiyonu, radyoterapi ve kemoterapi sonucu hastanın sağkalım süresi maximum 24 aya kadar uzatılabilmi
Externí odkaz:
https://doaj.org/article/3898ef9d2bfa4d12910e53eeaf8be9d2
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e58239 (2013)
Accumulation of peptide-linked DNA breaks contributes to neurodegeration in humans. This is typified by defects in tyrosyl DNA phosphodiesterase 1 (TDP1) and human hereditary ataxia. TDP1 primarily operates at single-strand breaks (SSBs) created by o
Externí odkaz:
https://doaj.org/article/760bf2c491c844b2a929b3d55dbe4e01
Autor:
Tom Stiff, Meryem Alagoz, Diana Alcantara, Emily Outwin, Han G Brunner, Ernie M H F Bongers, Mark O'Driscoll, Penny A Jeggo
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003360 (2013)
Mutations in ORC1, ORC4, ORC6, CDT1, and CDC6, which encode proteins required for DNA replication origin licensing, cause Meier-Gorlin syndrome (MGS), a disorder conferring microcephaly, primordial dwarfism, underdeveloped ears, and skeletal abnormal
Externí odkaz:
https://doaj.org/article/69eacb54876d4ebc8dd03f2134f20bbf
Publikováno v:
Journal of Molecular Neuroscience. 70:2077-2084
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive disease that causes acute or chronic hemolytic anemia and potentially leads to severe jaundice in response to oxidative agents. Capicua transcriptional repressor (CIC) is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace7ad3768792e4c30e4017cea47d31e
https://doi.org/10.1007/s12031-020-01614-8
https://doi.org/10.1007/s12031-020-01614-8
Autor:
Nasim Kherad, Meryem Alagoz
Publikováno v:
International Journal of Molecular Medicine
Genome editing techniques are considered to be one of the most challenging yet efficient tools for assisting therapeutic approaches. Several studies have focused on the development of novel methods to improve the efficiency of gene editing, as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce833dc2d87df76dcd0c4548c593fa1
https://doi.org/10.3892/ijmm.2020.4609
https://doi.org/10.3892/ijmm.2020.4609
Autor:
Huseyin Avni Solgun, Elif Sibel Aslan, Meryem Alagoz, Seyda Demirkol, Süreyya Bozkurt, Nasim Kherad, Alper Ozkılıc, Adnan Yuksel
X-lined intellectual disability (XLID), formerly known as X-lined mental retardation, is defined as genetically heterogeneous disorders with remarkable cognitive impairment and abnormal adaptive behaviour skills. This study demonstrates the Disc-larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f397ba349de72ac874390b5a812c98
https://doi.org/10.21203/rs.3.rs-692598/v1
https://doi.org/10.21203/rs.3.rs-692598/v1
Publikováno v:
Experimental and Therapeutic Medicine
alagoz, Meryem/0000-0002-6243-2146 WOS:000537686800007 PubMed ID: 32346411 The condition 3-methylglutaconic aciduria (3-MGA) with deafness, encephalopathy and Leigh-like (MEGDEL) syndrome, also known as 3-MGA IV, is one of a group of five rare metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609025a33d78b83ab035bc1d265e1ea0
https://doi.org/10.3892/etm.2020.8658
https://doi.org/10.3892/etm.2020.8658
Publikováno v:
Volume: 9, Issue: 4 715-720
Sakarya Tıp Dergisi
Sakarya Tıp Dergisi
Mental retardasyon genetik ve çevresel faktörlerin etkileri sonucu ortaya çıkan konjenital anomalilerdir. Genetik bozuklukların mental retardasyonun gelişmesindeki etkinliği göz önüne alındığında genetik tanının hastalığın teşhisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be3885d246b5ecfcc97987b5a968f8a
https://doi.org/10.31832/smj.589375
https://doi.org/10.31832/smj.589375
Autism spectrum disorders (ASD) are common heterogeneous neurodevelopmental disorders, characterized by disruptions in social interactions, communication, and limitations in behavior. Early diagnosis is an important step to prevent progression of ASD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a1c827d1918c18b5696393662ce15d
https://hdl.handle.net/20.500.12445/1072
https://hdl.handle.net/20.500.12445/1072