Causal Pathways from Enteropathogens to Environmental Enteropathy: Findings from the MAL-ED Birth Cohort Study

Autor: Margaret N. Kosek, Tahmeed Ahmed, Zulfiquar Bhutta, Laura Caulfield, Richard Guerrant, Eric Houpt, Gagandeep Kang, Margaret Kosek, Gwenyth Lee, Aldo Lima, Benjamin J.J. McCormick, James Platts-Mills, Jessica Seidman, Rebecca R. Blank, Michael Gottlieb, Stacey L. Knobler, Dennis R. Lang, Mark A. Miller, Karen H. Tountas, Zulfiqar A. Bhutta, William Checkley, Richard L. Guerrant, Carl J. Mason, Laura E. Murray-Kolb, William A. Petri, Jr., Jessica C. Seidman, Pascal Bessong, Rashidul Haque, Sushil John, Aldo A.M. Lima, Estomih R. Mduma, Reinaldo B. Oriá, Prakash Sunder Shrestha, Sanjaya Kumar Shrestha, Erling Svensen, Anita K.M. Zaidi, Cláudia B. Abreu, Angel Mendez Acosta, Imran Ahmed, A.M. Shamsir Ahmed, Asad Ali, Ramya Ambikapathi, Leah Barrett, Aubrey Bauck, Eliwaza Bayyo, Ladaporn Bodhidatta, Anuradha Bose, J. Daniel Carreon, Ram Krishna Chandyo, Vivek Charu, Hilda Costa, Rebecca Dillingham, Alessandra Di Moura, Viyada Doan, Jose Quirino Filho, Jhanelle Graham, Christel Hoest, Iqbal Hossain, Munirul Islam, M. Steffi Jennifer, Shiny Kaki, Beena Koshy, Álvaro M. Leite, Noélia L. Lima, Bruna L.L. Maciel, Mustafa Mahfuz, Cloupas Mahopo, Angelina Maphula, Monica McGrath, Archana Mohale, Milena Moraes, Francisco S. Mota, Jayaprakash Muliyil, Regisiana Mvungi, Gaurvika Nayyar, Emanuel Nyathi, Maribel Paredes Olortegui, Reinaldo Oria, Angel Orbe Vasquez, William K. Pan, John Pascal, Crystal L. Patil, Laura Pendergast, Silvia Rengifo Pinedo, Stephanie Psaki, Mohan Venkata Raghava, Karthikeyan Ramanujam, Muneera Rasheed, Zeba A. Rasmussen, Stephanie A. Richard, Anuradha Rose, Reeba Roshan, Barbara Schaefer, Rebecca Scharf, Srujan L. Sharma, Binob Shrestha, Rita Shrestha, Suzanne Simons, Alberto M. Soares, Rosa M.S. Mota, Sajid Soofi, Tor Strand, Fahmida Tofail, Rahul J. Thomas, Ali Turab, Manjeswori Ulak, Vivian Wang, Ladislaus Yarrot, Pablo Peñataro Yori, Didar Alam, Caroline Amour, Cesar Banda Chavez, Sudhir Babji, Rosa Rios de Burga, Julian Torres Flores, Jean Gratz, Ajila T. George, Dinesh Hariraju, Alexandre Havt, Priyadarshani Karunakaran, Robin P. Lazarus, Ila F. Lima, Dinesh Mondal, Pedro H.Q.S. Medeiros, Rosemary Nshama, Josiane Quetz, Shahida Qureshi, Sophy Raju, Anup Ramachandran, Rakhi Ramadas, A. Catharine Ross, Mery Siguas Salas, Amidou Samie, Kerry Schulze, E. Shanmuga Sundaram, Buliga Mujaga Swema, Dixner Rengifo Trigoso

Publikováno v: EBioMedicine, Vol 18, Iss C, Pp 109-117 (2017)

Background: Environmental enteropathy (EE), the adverse impact of frequent and numerous enteric infections on the gut resulting in a state of persistent immune activation and altered permeability, has been proposed as a key determinant of growth fail

Externí odkaz: https://doaj.org/article/c3ea0668870d4a51b813fae7c0c03278

The other Campylobacters: Not innocent bystanders in endemic diarrhea and dysentery in children in low-income settings.

Autor: Ruthly François, Pablo Peñataro Yori, Saba Rouhani, Mery Siguas Salas, Maribel Paredes Olortegui, Dixner Rengifo Trigoso, Nora Pisanic, Rosa Burga, Rina Meza, Graciela Meza Sanchez, Michael J Gregory, Eric R Houpt, James A Platts-Mills, Margaret N Kosek

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 2, p e0006200 (2018)

Campylobacter is one of the main causes of gastroenteritis worldwide. Most of the current knowledge about the epidemiology of this food-borne infection concerns two species, C. coli and C. jejuni. Recent studies conducted in developing countries and

Externí odkaz: https://doaj.org/article/12735c515ce345e29bf016eec8b1004b

Intestinal permeability and inflammation mediate the association between nutrient density of complementary foods and biochemical measures of micronutrient status in young children: results from the MAL-ED study

Autor: Erling Svensen, Gagandeep Kang, Dixner Rengifo Trigoso, M Munirul Islam, Benjamin J.J. McCormick, Ramya Ambikapathi, Sophy Raju, Rita Shrestha, Cláudia B. Abreu, Ram Krishna Chandyo, Maribel Paredes Olotegui, Gaurvika M. L. Nayyar, Archana Mohale, Margaret Kosek, Rebecca Blank, Álvaro M. Leite, Srujan Lam Sharma, Manjeswori Ulak, Richard L. Guerrant, Anup Ramachandran, Robin P. Lazarus, Josiane da Silva Quetz, AM Shamsir Ahmed, Estomih R. Mduma, Binob Shrestha, Anita K. M. Zaidi, Aubrey Bauck, Cesar Banda Chavez, Regisiana Mvungi, Silvia Rengifo Pinedo, Sanjaya K. Shrestha, Jean Gratz, Sudhir Babji, Priyadarshani Karunakaran, Pablo Peñataro Yori, José Q. Filho, Laura E. Murray-Kolb, Rosa Maria Salani Mota, Stephanie A. Richard, Ajila T. George, Sajid Bashir Soofi, Vivek Charu, Rosemary Nshama, Zeba A Rasmussen, M. Steffi Jennifer, Rahul J. Thomas, Ladislaus Blacy Yarrot, Alberto M. Soares, Noélia L. Lima, Laura L. Pendergast, Milena Lima de Moraes, Ila F. N. Lima, A. Catharine Ross, Eric R. Houpt, Ladaporn Bodhidatta, Laura E. Caulfield, Estomih Mduma, Tahmeed Ahmed, Jayaprakash Muliyil, Mery Siguas Salas, Rebecca Dillingham, Shahida Qureshi, Sushil John, Caroline Amour, Francisco Suetônio Bastos Mota, Pedro H. Q. S. Medeiros, Angel Mendez Acosta, Iqbal Hossain, Eliwaza Bayyo, Dinesh Mondal, Imran Ahmed, Buliga Mujaga Swema, H. Costa, Michael Gottlieb, Beena Koshy, Mark A. Miller, Vivian Ota Wang, Jhanelle Graham, Muneera A. Rasheed, Alexandre Havt, Bruna Leal Lima Maciel, Cloupas Mahopo, Anuradha Bose, Prakash S. Shrestha, Jessica C. Seidman, Monica McGrath, Alessandra Di Moura, Ali Turab, Viyada Doan, William Pan, Pascal O. Bessong, Didar Alam, Rakhi Ramadas, Tor A. Strand, Reinaldo B. Oriá, Stephanie Psaki, Karthikeyan Ramanujam, John M. Pascal, Rosa Burga, Amidou Samie, William A. Petri, Dinesh Hariraju, Dennis Lang, Christel Hoest, Robert E. Black, Karen H. Tountas, Mohan Venkata Raghava, Angel Orbe Vasquez, Zulfiqar A Bhutta, Emanuel Nyathi, Julian Torres Flores, Rashidul Haque, Leah J. Barrett, J. Daniel Carreon, Carl J. Mason, Zulfiqar A. Bhutta, Stacey Knobler, Rebecca J. Scharf, Suzanne Simons, Kerry Schulze, Crystal L. Patil, Aldo A. M. Lima, Reeba Roshan, Angelina Maphula, Maribel Paredes Olortegui, James A Platts-Mills, Fahmida Tofail, Shiny Kaki, Asad Ali, Gwenyth O. Lee, Sanjaya K. Shrestra, Mustafa Mahfuz, Shanmuga Sundaram, William Checkley, Barbara A. Schaefer

Publikováno v: The American Journal of Clinical Nutrition

Background Environmental enteric dysfunction (EED) is thought to increase the risk of micronutrient deficiencies, but few studies adjust for dietary intakes and systemic inflammation. Objective We tested whether EED is associated with micronutrient d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0938431c2ba058b258d7abe8b5c0e903
https://doi.org/10.1093/ajcn/nqz151

Gut Microbiota Features Associated With Campylobacter Burden and Postnatal Linear Growth Deficits in a Peruvian Birth Cohort

Autor: Saba Rouhani, Pablo Peñataro Yori, Eric R. Houpt, Mery Siguas Salas, Lawrence H. Moulton, Michael J. Barratt, Maribel Paredes Olortegui, Jeffrey I. Gordon, Margaret Kosek, Dixner Rengifo Trigoso, Nicholas W. Griffin

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Background Campylobacter infection is associated with impaired growth of children, even in the absence of symptoms. To examine the underlying mechanisms, we evaluated associations between Campylobacter infection, linear growth, and fecal microbial co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ee8672f9f84bf0356992d62a27b5aa
http://europepmc.org/articles/PMC7428392

Penalized regression models to select biomarkers of environmental enteric dysfunction associated with linear growth acquisition in a Peruvian birth cohort

Autor: Francesca Schiaffino, Ruthly François, Maribel Paredes Olortegui, Pablo Peñataro Yori, Lawrence H. Moulton, Fahmina Fardus-Reid, Dixner Rengifo Trigoso, Peter S. Kosek, Mery Siguas Salas, Margaret Kosek, Jonathan R. Swann, Josh M. Colston

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007851 (2019)

Environmental enteric dysfunction (EED) is associated with chronic undernutrition. Efforts to identify minimally invasive biomarkers of EED reveal an expanding number of candidate analytes. An analytic strategy is reported to select among candidate b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e895e65d204ae54d63e4ced1d088633
http://europepmc.org/articles/PMC6881068