Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mery Santivañez-Veliz"'
Autor:
Rocio Paucar-Bernabé, Elsa Moreno-Viguri, Rubén Martín-Escolano, Mery Santivañez-Veliz, Amaya Azqueta, Nuria Cirauqui, Manuel Sánchez-Moreno, Silvia Pérez-Silanes
Publikováno v:
Proceedings, Vol 1, Iss 6, p 659 (2017)
Chagas disease (CD) is a neglected tropical disease caused by the parasite Trypanosoma cruzi [1]. [...]
Externí odkaz:
https://doaj.org/article/849c25589b694c129681dd5690071011
Autor:
Mery Santivañez-Veliz, Elsa Moreno-Viguri, Silvia Pérez-Silanes, Chung Man Chin, Jean Leandro dos Santos, Guilherme Felipe dos Santos Fernandes, Rocio Paucar
Publikováno v:
Journal of Heterocyclic Chemistry. 54:2380-2388
Quinoxaline 1,4-di-N-oxide (QdNO) and N-acylhydrazone subunit are considered privileged scaffolds in medicinal chemistry because of its wide spectrum of biological activities, such as antibacterial, antitubercular, antiviral, anticancer, and antifung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc81885c1759b7d61eb77f5e4c4f3b70
https://doi.org/10.1002/jhet.2830
https://doi.org/10.1002/jhet.2830
Autor:
Marina Jimenez-Lopez, Rubén Martín-Escolano, Salvador Zamora Ledesma, Clotilde Marín, Adela López de Cerain, Carmen Jiménez-Montes, Manuel Sánchez-Moreno, Mery Santivañez-Veliz, Elsa Moreno-Viguri, Amaya Azqueta, Silvia Pérez-Silanes, Álvaro Martín-Montes, Nuria Cirauqui
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
Chagas disease is a neglected tropical disease with 6-7 million people infected worldwide and there is no effective treatment. Therefore, there is an urgent need to continue researching in order to discover novel therapeutic alternatives. We present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423c105944489331189f414f684b15cf
https://doi.org/10.1021/acs.jmedchem.6b00784
https://doi.org/10.1021/acs.jmedchem.6b00784
Autor:
Silvia Pérez-Silanes, Rubén Martín-Escolano, Clotilde Marín, Amaya Azqueta, Elsa Moreno-Viguri, Encarnación Medina-Carmona, Rocio Paucar, Nuria Cirauqui, Angel L. Pey, Mery Santivañez-Veliz, Manuel Sánchez-Moreno, Álvaro Martín-Montes
Publikováno v:
Journal of medicinal chemistry. 61(13)
Chagas disease is a potentially life-threatening and neglected tropical disease caused by Trypanosoma cruzi. One of the most important challenges related to Chagas disease is the search for new, safe, effective, and affordable drugs since the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556b6a5a27c069e0f7cf60779c50ebfc
https://pubmed.ncbi.nlm.nih.gov/29883536
https://pubmed.ncbi.nlm.nih.gov/29883536
Autor:
Catalina Lopez-Gonzalez, Silvia Pérez-Silanes, Carmen Sanmartín, Mery Santivañez-Veliz, Manuel Sánchez-Moreno, Rubén Martín-Escolano, Carmen Jiménez-Montes, Ramón Gutiérrez Sánchez, Álvaro Martín-Montes, Clotilde Marín, Elsa Moreno-Viguri
Publikováno v:
Dadun: Depósito Académico Digital de la Universidad de Navarra
Universidad de Navarra
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
Universidad de Navarra
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
SUMMARYLeishmaniasis is one of the world's most neglected diseases, and it has a worldwide prevalence of 12 million. There are no effective human vaccines for its prevention, and treatment is hampered by outdated drugs. Therefore, research aiming at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20912608aadf89b07e662b687178409
https://hdl.handle.net/10171/61121
https://hdl.handle.net/10171/61121
Autor:
Rocio Paucar, Marlus Chorilli, Konstantin Chegaev, Paula Carolina de Souza, Priscila Longhin Bosquesi, Leonardo B. Marino, Chung Man Chin, Guilherme Felipe dos Santos Fernandes, Patrícia Bento da Silva, Silvia Pérez-Silanes, Yuehong Wang, Jean Leandro dos Santos, Caio Sander Paiva Silva, Mariana Cristina Solcia, Mery Santivañez-Veliz, Carlos Alberto de Souza Costa, Sang-Hyun Cho, Elsa Moreno-Viguri, Camila Maríngolo Ribeiro, Luiz Pedro S. de Carvalho, Stefano Guglielmo, Loretta Lazzarato, Debbie M. Hunt, Roberta Fruttero, Scott G. Franzblau, Fernando Rogério Pavan
Publikováno v:
Journal of Medicinal Chemistry
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Tuberculosis, caused by the Mycobacterium tuberculosis (Mtb), is the infectious disease responsible for the highest number of deaths worldwide. Herein, 22 new N-oxide- containing compounds were synthesized followed by in vitro and in vivo evaluation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f10a0cede143f3672010af8c235a1a
https://pubmed.ncbi.nlm.nih.gov/28968083
https://pubmed.ncbi.nlm.nih.gov/28968083
Autor:
Amaya Azqueta, Rocio Paucar-Bernabé, Manuel Sánchez-Moreno, Elsa Moreno-Viguri, Mery Santivañez-Veliz, Rubén Martín-Escolano, Nuria Cirauqui, Silvia Pérez-Silanes
Publikováno v:
Proceedings, Vol 1, Iss 6, p 659 (2017)
Chagas disease (CD) is a neglected tropical disease caused by the parasite Trypanosoma cruzi [1]. [...]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbff101ee751d26f1099e64073cf129
https://www.mdpi.com/2504-3900/1/6/659
https://www.mdpi.com/2504-3900/1/6/659
Autor:
Hugo Cerecetto, Mercedes González, Elsa Moreno-Viguri, Elena Lizarraga, Silvia Pérez-Silanes, Mery Santivañez-Veliz, Javier Varela
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
The development and validation of an analytical method for the simultaneous analysis of five neutral lipids in Trypanosoma cruzi epimastigotes by GC-MS is presented in this study. The validated method meets all validation parameters for all component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e33f30b515ef03205901ddb6e4ec978
https://hdl.handle.net/10171/51718
https://hdl.handle.net/10171/51718
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
Twenty-four quinoxaline derivatives were evaluated for their antimycobacterial activity using BacTiter-Glo microbial cell viability assay. Five compounds showed MIC values < 3.1 μM and IC50 values < 1.5 μM in primary screening and therefore, they w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3943c2b7dfdd94b47869c05b573b2479
https://pubmed.ncbi.nlm.nih.gov/27025343
https://pubmed.ncbi.nlm.nih.gov/27025343
Autor:
Marina Jimenez-Lopez, Álvaro Martín-Montes, Amaya Azqueta, Manuel Sánchez-Moreno, Salvador Zamora Ledesma, Silvia Pérez-Silanes, Rubén Martín-Escolano, Carmen Jiménez-Montes, Elsa Moreno-Viguri, Clotilde Marín, Mery Santivañez-Veliz, Nuria Cirauqui, Adela López de Cerain
Publikováno v:
Journal of Medicinal Chemistry. 60:2604-2604
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d068531a13ec7125fd5152563d4122
https://doi.org/10.1021/acs.jmedchem.7b00263
https://doi.org/10.1021/acs.jmedchem.7b00263