Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mervyn W.O. Liew"'
Autor:
Freddy Franklin, Leong Huat Chua, Ismail Aziah, Mervyn W.O. Liew, Chun Wie Chong, Eugene Boon Beng Ong, Amy Amilda Anthony
Publikováno v:
Medical Microbiology and Immunology. 209:593-601
Typhoid fever is a disease caused by Salmonella Typhi that was implicated in millions of illnesses worldwide annually. Individuals that do not recover fully from typhoid fever can become asymptomatic carriers of the disease. Host antibodies against t
Autor:
Soo Choon Tan, Mohd Nor Norazmi, Ping Ying Lye, Shin-ichi Iwamoto, Eiji Kotani, Syamsiah Aini Shohaimi, Mervyn W.O. Liew, Toshihiro Nagamine, Niny Fariza Junoh, Suriani Mohd Noor, Hajime Mori
Publikováno v:
Process Biochemistry. 90:204-214
Recombinant hemagglutinin-neuraminidase (HN) based subunit vaccine, which is non-infectious and can be produced using insect cell-culture systems, is a potential alternative to conventional live and inactivated Newcastle disease virus (NDV) vaccines.
Publikováno v:
Journal of Biotechnology. :34-41
An intensified process was developed that enables high level production of recombinant core streptavidin (cSAV), a non-glycosylated tetrameric protein utilised in a wide range of applications. A pH-stat fed-batch feeding strategy was employed to achi
Publikováno v:
Journal of Chromatography B. 1148:122148
Screening for potential drug-drug interaction (DDI) or herb-drug interaction (HDI) using in vitro cytochrome P450 inhibition (IVCI) assays requires robust analytical methods with high sensitivity and reproducibility. Utilization of liquid chromatogra
Publikováno v:
Biochemical Engineering Journal. 68:120-128
An emerging paradigm to quickly and cost-effectively manufacture virus-like particle (VLP) biopharmaceuticals involves VLP subunit production in highly productive bacterial hosts, followed by assembly in a controlled cell-free environment. Study of c
Publikováno v:
Biochemical Engineering Journal. 67:88-96
Virus-like particles (VLPs) have been developed as safe and efficacious vaccines, and are increasingly used as carriers for foreign peptide epitopes in modular architectures. An emerging technology for low-cost and rapid-response VLP vaccine manufact
Publikováno v:
Journal of Biotechnology. 150:224-231
This study demonstrates the feasibility of large-scale production of murine polyomavirus VP1 protein in recombinant Escherichia coli as pentamers which are able to subsequently self-assemble in vitro into virus-like particles (VLPs). High-cell-densit