Výsledky vyhledávání - "Mervi Laakso"

Data from Estrogen Receptor β Expression Is Associated with Tamoxifen Response in ERα-Negative Breast Carcinoma

Autor: Mårten Fernö, Åke Borg, Jorma Isola, Per Malmström, Carsten Peterson, Patrik Edén, Cecilia Hegardt, Mervi Laakso, Lao H. Saal, Pär-Ola Bendahl, Sofia K. Gruvberger-Saal

Purpose: Endocrine therapies, such as tamoxifen, are commonly given to most patients with estrogen receptor (ERα)–positive breast carcinoma but are not indicated for persons with ERα-negative cancer. The factors responsible for response to tamoxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da10c0df3e0eaa0907b1583792ff058
https://doi.org/10.1158/1078-0432.c.6518757.v1

Zobrazit plný text záznamu

Supplementary Data from Estrogen Receptor β Expression Is Associated with Tamoxifen Response in ERα-Negative Breast Carcinoma

Autor: Mårten Fernö, Åke Borg, Jorma Isola, Per Malmström, Carsten Peterson, Patrik Edén, Cecilia Hegardt, Mervi Laakso, Lao H. Saal, Pär-Ola Bendahl, Sofia K. Gruvberger-Saal

Supplementary Materials and Methods, along with Supplementary Figure S1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011ae9bf6254e59d7711cccdfa686434
https://doi.org/10.1158/1078-0432.22441866.v1

Zobrazit plný text záznamu

Supplementary Information, Methods, Table 1, Figures 1-7 from 3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Supplementary Information, Methods, Table 1, Figures 1-7 from 3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25abfdbbb75ffe70019e086b41b57e62
https://doi.org/10.1158/0008-5472.22379426.v1

Zobrazit plný text záznamu

Data from 3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Lesions of ERBB2, PTEN, and PIK3CA activate the phosphatidylinositol 3-kinase (PI3K) pathway during cancer development by increasing levels of phosphatidylinositol-3,4,5-triphosphate (PIP3). 3-Phosphoinositide-dependent kinase 1 (PDK1) is the first n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b8ae99672f79cca8bc9ea987720b521
https://doi.org/10.1158/0008-5472.c.6499247.v1

Zobrazit plný text záznamu

3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Publikováno v: Cancer Research. 69:6299-6306

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe91b98c3abfc7d6d0f4280ad0203348
https://doi.org/10.1158/0008-5472.can-09-0820

Zobrazit plný text záznamu

Estrogen Receptor β Expression Is Associated with Tamoxifen Response in ERα-Negative Breast Carcinoma

Autor: Mårten Fernö, Cecilia Hegardt, Pär-Ola Bendahl, Lao H. Saal, Åke Borg, Jorma Isola, Mervi Laakso, Carsten Peterson, Per-Uno Malmström, Sofia K. Gruvberger-Saal, Patrik Edén

Publikováno v: Clinical Cancer Research. 13:1987-1994

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe3080b3dddbb58f04b8d42392db328
https://doi.org/10.1158/1078-0432.ccr-06-1823

Zobrazit plný text záznamu

Virtual Microscopy in Prostate Histopathology: Simultaneous Viewing of Biopsies Stained Sequentially With Hematoxylin and Eosin, and α-Methylacyl-Coenzyme A Racemase/p63 Immunohistochemistry

Autor: Mikael Lundin, H. Helin, Johan Lundin, Heikki Helin, Mervi Laakso, Jorma Isola

Publikováno v: Journal of Urology. 175:495-499

Histopathological diagnosis of small focus carcinomas in prostatic needle biopsies is often assisted by IHC. To make a definitive diagnosis the pathologist must compare IHC findings with hematoxylin and eosin stained tissue morphology. We introduce w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916c15e70b2e6971ea7df94cb3cc264e
https://doi.org/10.1016/s0022-5347(05)00164-3

Zobrazit plný text záznamu

Cytokeratin 5/14-positive breast cancer: true basal phenotype confined to BRCA1 tumors

Autor: Åke Borg, Niklas Loman, Mervi Laakso, Jorma Isola

Publikováno v: Modern Pathology. 18:1321-1328

Breast ducts contain two types of epithelial cells, inner luminal cells and outer basal/myoepithelial cells. These cells can be distinguished by their immunophenotype. Cytokeratins (CKs) 8 and 18 are expressed in the luminal layer, whereas CK5/14 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c34bd83886eebb8598dca14a2a4613
https://doi.org/10.1038/modpathol.3800456

Zobrazit plný text záznamu

Basoluminal carcinoma: a new biologically and prognostically distinct entity between basal and luminal breast cancer

Autor: Nils Wilking, Jonas Bergh, Mervi Laakso, Per-Uno Malmström, Bjoern Erikstein, Jorma Isola, Minna Tanner, Pirkko Kellokumpu-Lehtinen, Tom Wiklund, Jonas Nilsson

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 12(14 Pt 1)

Purpose: Breast carcinomas expressing basal epithelium cytokeratins constitute a tumor subgroup that is typically hormone receptor negative and shows a distinct gene expression profile. Based on variable basal cytokeratin immunostaining patterns, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b64fa33fa245aca004be1d4b53fbd6
https://pubmed.ncbi.nlm.nih.gov/16857790

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání