Generation of genetically matched hiPSC lines from two mosaic facioscapulohumeral dystrophy type 1 patients

Autor: Erik van der Wal, Bianca den Hamer, Patrick J. van der Vliet, Merve Tok, Tom Brands, Bert Eussen, Richard J.L.F. Lemmers, Christian Freund, Annelies de Klein, Ronald A.M. Buijsen, Willeke M.C. van Roon-Mom, Rabi Tawil, Silvère M. van der Maarel, Jessica C. de Greef

Publikováno v: Stem Cell Research, Vol 40, Iss , Pp - (2019)

Facioscapulohumeral dystrophy type 1 (FSHD1) is caused by contraction of the D4Z4 repeat array on chromosome 4q resulting in sporadic misexpression of the transcription factor DUX4 in skeletal muscle tissue. In ~4% of families, de novo D4Z4 contracti

Externí odkaz: https://doaj.org/article/85deb5651a0140ff82313268a573d294

Generation of 5 induced pluripotent stem cell lines, LUMCi007-A and B and LUMCi008-A, B and C, from 2 patients with Huntington disease

Autor: Willeke M. C. van Roon-Mom, N. Ahmad Aziz, Bert Eussen, Barry A. Pepers, Linda M. van der Graaf, Tom Brands, Merve Tok, Merel W. Boogaard, Sarah L. Gardiner, Annelies de Klein, Ronald A.M. Buijsen, Christian Freund

Publikováno v: Stem cell research 39, 101498 (2019). doi:10.1016/j.scr.2019.101498
Stem Cell Research, 39. ELSEVIER
Stem Cell Research, Vol 39, Iss, Pp-(2019)
Stem Cell Research, 39:Unsp 101498. Elsevier Inc.

Huntington disease (HD) is an autosomal dominant, neurodegenerative disease caused by a CAG repeat expansion within the coding sequence of the HTT gene, resulting in a highly toxic protein with an expanded polyglutamine stretch that forms typical pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c761e2035dacff6992c45c760cd1347
https://hdl.handle.net/1887/122259

Influence of colonic mesenteric area on the number of lymph node retrieval for colon cancer: a prospective cohort study

Autor: Nadir Adnan Hacım, Ahmet Akbaş, Yigit Ulgen, Talar Vartanoglu Aktokmakyan, Serhat Meric, Merve Tokocin, Onder Karabay, Yuksel Altinel

Publikováno v: Annals of Coloproctology, Vol 39, Iss 1, Pp 77-84 (2023)

Purpose The minimum harvested 12 lymph nodes (LNs) is regarded as the limit for accurate staging of nodal status in colorectal cancer patients. Besides the association of the lengths of resected intestinal segments and vascular pedicles, the mesocoli

Externí odkaz: https://doaj.org/article/040d4ea0efff4a78a2310ef99797e98e

Association of Preoperative Risk Factors and Mortality in Older Patients following Emergency Abdominal Surgery: A Retrospective Cohort Study

Autor: Nadir Adnan Hacım, Ahmet Akbaş, Yigit Ulgen, Talar Vartanoglu Aktokmakyan, Serhat Meric, Merve Tokocin, Onder Karabay, Gulcin Ercan, Yuksel Altinel

Publikováno v: Annals of Geriatric Medicine and Research, Vol 25, Iss 4, Pp 252-259 (2021)

Background Older patients undergoing emergency laparotomy have high morbidity and mortality rates. Preoperative risk assessment with good predictors is an appropriate measure in this population. Frailty status is significantly associated with postope

Externí odkaz: https://doaj.org/article/97c158b540da4f48b8cae9cc44faf9a5

How Can We Manage the Therapeutic Approach of Acute Diverticulitis Regarding the Number of Attacks?

Autor: Yüksel Altınel, Nadir Adnan Hacım, Merve Tokoçin, Serhat Meriç, Ahmet Akbaş

Publikováno v: Turkish Journal of Colorectal Disease, Vol 31, Iss 1, Pp 49-55 (2021)

Aim:The risk of acute diverticulitis (AD) increases with each attack and the decision of therapeutic management is getting more complicated. We aimed to investigate the effective features of the number of attacks.Method:Two hundred thirty six patient

Externí odkaz: https://doaj.org/article/5f3c0eab61854a889b990ef7b22a8a05