Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Merve Avar"'
Autor:
Daniel Heinzer, Merve Avar, Daniel Patrick Pease, Ashutosh Dhingra, Jiang-An Yin, Elke Schaper, Berre Doğançay, Marc Emmenegger, Anna Spinelli, Kevin Maggi, Andra Chincisan, Simon Mead, Simone Hornemann, Peter Heutink, Adriano Aguzzi
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
The cellular prion protein PrPC is necessary for prion replication, and its reduction greatly increases life expectancy in animal models of prion infection. Hence the factors controlling the levels of PrPC may represent therapeutic targets against hu
Externí odkaz:
https://doaj.org/article/0bb9cfda63ef41b79c0071537284dc38
Autor:
Marc Emmenegger, Elena De Cecco, Marian Hruska‐Plochan, Timo Eninger, Matthias M Schneider, Melanie Barth, Elena Tantardini, Pierre de Rossi, Mehtap Bacioglu, Rebekah G Langston, Alice Kaganovich, Nora Bengoa‐Vergniory, Andrès Gonzalez‐Guerra, Merve Avar, Daniel Heinzer, Regina Reimann, Lisa M Häsler, Therese W Herling, Naunehal S Matharu, Natalie Landeck, Kelvin Luk, Ronald Melki, Philipp J Kahle, Simone Hornemann, Tuomas P J Knowles, Mark R Cookson, Magdalini Polymenidou, Mathias Jucker, Adriano Aguzzi
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 9, Pp n/a-n/a (2021)
Abstract While the initial pathology of Parkinson’s disease and other α‐synucleinopathies is often confined to circumscribed brain regions, it can spread and progressively affect adjacent and distant brain locales. This process may be controlled
Externí odkaz:
https://doaj.org/article/7994f076bf964ea9bf26f7f4ba6a434a
Autor:
Silvia Sorce, Mario Nuvolone, Giancarlo Russo, Andra Chincisan, Daniel Heinzer, Merve Avar, Manuela Pfammatter, Petra Schwarz, Mirzet Delic, Micha Müller, Simone Hornemann, Despina Sanoudou, Claudia Scheckel, Adriano Aguzzi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008653 (2020)
The clinical course of prion diseases is accurately predictable despite long latency periods, suggesting that prion pathogenesis is driven by precisely timed molecular events. We constructed a searchable genome-wide atlas of mRNA abundance and splici
Externí odkaz:
https://doaj.org/article/3378ce74ef8f40b7a548373f25fdab25
Autor:
Micha Müller, Merve Avar, Daniel Heinzer, Marc Emmenegger, Adriano Aguzzi, Lucas Pelkmans, Scott Berry
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/61f021b0ef1a424ab96c6b78a336729c
Autor:
Annika Keller, Mario Nuvolone, Irina Abakumova, Andra Chincisan, Regina Reimann, Merve Avar, Daniel Heinzer, Simone Hornemann, Josephin Wagner, Daniel Kirschenbaum, Fabian F Voigt, Caihong Zhu, Luca Regli, Fritjof Helmchen, Adriano Aguzzi
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007424 (2018)
Transmissible spongiform encephalopathies (TSEs) are caused by the prion, which consists essentially of PrPSc, an aggregated, conformationally modified form of the cellular prion protein (PrPC). Although TSEs can be experimentally transmitted by intr
Externí odkaz:
https://doaj.org/article/154e8661ae744cb885de7f2073c95e14
Autor:
Simon Mead, Simone Hornemann, Marc Emmenegger, Elke Schaper, Kevin Maggi, Peter Heutink, Jiang-An Yin, Anna Spinelli, Ashutosh Dhingra, Daniel Heinzer, Berre Doğançay, Merve Avar, Daniel Patrick Pease, Adriano Aguzzi, Andra Chincisan
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
PLoS pathogens 17(10), e1010013 (2021). doi:10.1371/journal.ppat.1010013
PLoS Pathogens, Vol 17, Iss 10, p e1010013 (2021)
PLoS Pathogens
PLoS pathogens 17(10), e1010013 (2021). doi:10.1371/journal.ppat.1010013
PLoS Pathogens, Vol 17, Iss 10, p e1010013 (2021)
PLoS Pathogens
The cellular prion protein PrPC is necessary for prion replication, and its reduction greatly increases life expectancy in animal models of prion infection. Hence the factors controlling the levels of PrPC may represent therapeutic targets against hu
Autor:
Micha Müller, Merve Avar, Daniel Heinzer, Marc Emmenegger, Adriano Aguzzi, Lucas Pelkmans, Scott Berry
Publikováno v:
Scientific Data
Scientific Data, Vol 8, Iss 1, Pp 1-13 (2021)
Scientific Data, Vol 8, Iss 1, Pp 1-13 (2021)
Coordination of RNA abundance and production rate with cell size has been observed in diverse organisms and cell populations. However, how cells achieve such ‘scaling’ of transcription with size is unknown. Here we describe a genome-wide siRNA sc
Autor:
Adriano Aguzzi, Mathias Jucker, Magdalini Polymenidou, Mark R. Cookson, Tuomas P. J. Knowles, Simone Hornemann, Philipp J. Kahle, Ronald Melki, Kelvin Luk, Natalie Landeck, Naunehal S. Matharu, Therese W. Herling, Lisa M. Häsler, Regina Reimann, Daniel Heinzer, Merve Avar, Andrès Gonzalez-Guerra, Nora Bengoa-Vergniory, Alice Kaganovich, Rebekah G. Langston, Mehtap Bacioglu, Pierre de Rossi, Elena Tantardini, Melanie Barth, Matthias M. Schneider, Timo Eninger, Marian Hruska-Plochan, Elena De Cecco, Marc Emmenegger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fcdc8bbb95533537cf9843e591965a2
https://doi.org/10.15252/rc.2022275692
https://doi.org/10.15252/rc.2022275692
Autor:
Pierre De Rossi, Therese W. Herling, Marian Hruska-Plochan, Nora Bengoa-Vergniory, Ronald Melki, Natalie Landeck, Mathias Jucker, Simone Hornemann, Philipp J. Kahle, Rebekah G. Langston, Andrés González-Guerra, Merve Avar, Melanie Barth, Timo Eninger, Lisa M. Häsler, Kelvin C. Luk, Mehtap Bacioglu, Daniel Heinzer, Elena Tantardini, Marc Emmenegger, Tuomas P. J. Knowles, Magdalini Polymenidou, Elena De Cecco, Alice Kaganovich, Matthias Schneider, Naunehal S. Matharu, Mark R. Cookson, Adriano Aguzzi, Regina Reimann
While the initial pathology of Parkinson’s disease and other α-synucleinopathies is often confined to circumscribed brain regions, it can spread and progressively affect adjacent and distant brain locales. This process may be controlled by cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd694eabd8cc6283df3874908afc5fa9
https://doi.org/10.1101/2021.04.25.441302
https://doi.org/10.1101/2021.04.25.441302
Autor:
Merve Avar, Scott Berry, Marc Emmenegger, Lucas Pelkmans, Daniel Heinzer, Adriano Aguzzi, Micha Müller
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a6805437a0837ad00be78ae34c1f99