Výsledky vyhledávání - "Merton Bernfield"

Inhibition by the Soluble Syndecan-1 Ectodomains Delays Wound Repair in Mice Overexpressing Syndecan-1

Autor: Varpu Elenius, Klaus Elenius, Ofer Reizes, Martin Götte, Merton Bernfield

Publikováno v: Journal of Biological Chemistry. 279:41928-41935

Wound repair is a tightly regulated process stimulated by proteases, growth factors, and chemokines, which are modulated by heparan sulfate. To characterize further the role of the heparan sulfate proteoglycan syndecan-1 in wound repair, we generated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b52cd81a0fef7b395cb879e3f420f06
https://doi.org/10.1074/jbc.m404506200

Zobrazit plný text záznamu

Syndecan-1 and -4 Synthesized Simultaneously by Mouse Mammary Gland Epithelial Cells Bear Heparan Sulfate Chains That Are Apparently Structurally Indistinguishable

Autor: John T. Gallagher, Merton Bernfield, Jianying Dong, Jon A. Deakin, Olga Goldberger, Masahiro Zako

Publikováno v: Journal of Biological Chemistry. 278:13561-13569

Many of the biological functions attributed to cell surface heparan sulfate (HS) proteoglycans, including the Syndecan family, are elicited through the interaction of their HS chains with soluble extracellular molecules. Tightly controlled, cell-spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ba64845fb9143e5f0e6068800b9f28
https://doi.org/10.1074/jbc.m209658200

Zobrazit plný text záznamu

Identification and Characterization of Three Drosophila melanogaster Glucuronyltransferases Responsible for the Synthesis of the Conserved Glycosaminoglycan-Protein Linkage Region of Proteoglycans

Autor: John Lincecum, Kazuyuki Sugahara, Kazunori Tsuchida, Merton Bernfield, Byung-Taek Kim, Hiroshi Kitagawa

Publikováno v: Journal of Biological Chemistry. 278:9116-9124

The Drosophila melanogaster genome contains three putative glucuronyltransferases homologous to human GlcAT-I and GlcAT-P. These enzymes are predicted to be β1,3-glucuronyltransferases involved in the synthesis of the glycosaminoglycan (GAG)-protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e5909e06219291f42b73cbf5addb7ec
https://doi.org/10.1074/jbc.m209344200

Zobrazit plný text záznamu

Structural Characterization of Heparan Sulfate and Chondroitin Sulfate of Syndecan-1 Purified from Normal Murine Mammary Gland Epithelial Cells

Autor: Kazuyuki Sugahara, Masahiro Zako, Shuhei Yamada, Momoyo Ueno, Merton Bernfield

Publikováno v: Journal of Biological Chemistry. 276:29134-29140

Syndecan-1, present on the surfaces of normal murine mammary gland epithelial cells, is a transmembrane hybrid proteoglycan, which bears glycosaminoglycan (GAG) side chains of heparan sulfate (HS) and chondroitin sulfate (CS). Purified syndecan-1 ect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6aa60c12c9e64ead51d74fabb608f31
https://doi.org/10.1074/jbc.m102089200

Zobrazit plný text záznamu

Transgenic Expression of Syndecan-1 Uncovers a Physiological Control of Feeding Behavior by Syndecan-3

Autor: Gregory S. Barsh, Merton Bernfield, Zihua Wang, Michael T. Hinkes, Ofer Reizes, Rexford Ahima, Olga Goldberger, Heikki Rauvala, John Lincecum, Marko Kaksonen, Li Huang

Publikováno v: Cell. 106:105-116

Transgenic expression in the hypothalamus of syndecan-1, a cell surface heparan sulfate proteoglycan (HSPG) and modulator of ligand-receptor encounters, produces mice with hyperphagia and maturity-onset obesity resembling mice with reduced action of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af857cc7859109fc24255add9e65522
https://doi.org/10.1016/s0092-8674(01)00415-9

Zobrazit plný text záznamu

Exploitation of syndecan-1 shedding by Pseudomonas aeruginosa enhances virulence

Autor: Gerald B. Pier, Pyong Woo Park, Michael T. Hinkes, Merton Bernfield

Publikováno v: Nature. 411:98-102

Cell-surface heparan sulphate proteoglycans (HSPGs) are ubiquitous and abundant receptors/co-receptors of extracellular ligands, including many microbes. Their role in microbial infections is poorly defined, however, because no cell-surface HSPG has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8ad7916183f274cd288a0c1438bf84
https://doi.org/10.1038/35075100

Zobrazit plný text záznamu

The curly tail mouse model of human neural tube defects demonstrates normal spinal cord differentiation at the level of the meningomyelocele: implications for fetal surgery

Autor: S M Manning, Merton Bernfield, Mehmet Selçuki

Publikováno v: Child's Nervous System. 17:19-23

The paralysis associated with lumbosacral meningomyelocele has been attributed both to myelodysplasia and to degeneration of the exposed neural tissue. Surgically created dysraphism shows that exposure of an intact spinal cord in a genetically normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bc28fdb34bfb2112a4fc0e334e1f56
https://doi.org/10.1007/s003810000401

Zobrazit plný text záznamu

Heparan sulfate and chondroitin sulfate proteoglycans inhibit E-selectin binding to endothelial cells

Autor: Merton Bernfield, Huiming Wang, Masato Kato, Jianying Luo, Joyce Bischoff

Publikováno v: Journal of Cellular Biochemistry. 80:522-531

E-selectin is a cell adhesion molecule involved in the initial rolling and adhesion of leukocytes to the endothelium during inflammation. In addition, in vitro studies have suggested that an interaction between E-selectin and binding sites such as si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70120c7df624b2b2d98d43466b650e03
https://doi.org/10.1002/1097-4644(20010315)80:4<522::aid-jcb1006>3.0.co

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání