Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Mert Gur"'
Autor:
Zhuan Zhou, Zhiwei Feng, Dong Hu, Peng Yang, Mert Gur, Ivet Bahar, Massimo Cristofanilli, William J. Gradishar, Xiang-qun Xie, Yong Wan
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 98-111 (2019)
Background: Triple negative breast cancers (TNBCs) have a poor prognosis and are not amenable to endocrine- or HER2-targeted therapies. The malignant and invasive feature of TNBCs is correlated with its high cancer stem cell population. Recent result
Externí odkaz:
https://doaj.org/article/6b28ecdbf4e348ec87e8016212cb946a
Autor:
Mert Gur
Publikováno v:
Uludağ University Journal of The Faculty of Engineering, Vol 21, Iss 2, Pp 145-158 (2016)
Bu çalışmada balkabağının akışkan yataklı kurutucuda kurutma karakteristiği incelenmiştir. Deneyler için balkabağı tarla hasadından sonra küp şeklinde kesilerek, 50, 60 ve 70 °C’deki üç farklı sıcaklıktaki hava ile akışkan
Externí odkaz:
https://doaj.org/article/64998a98cba74716b221947e5b18b1e5
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 4, p e1003521 (2014)
Biomolecular conformational transitions are essential to biological functions. Most experimental methods report on the long-lived functional states of biomolecules, but information about the transition pathways between these stable states is generall
Externí odkaz:
https://doaj.org/article/de61a480973d47b6b6dacbc952c389f6
Autor:
Gözde Eskici, Mert Gur
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66178 (2013)
Alzheimer's disease is the most common form of dementia. It is a neurodegenerative and incurable disease that is associated with the tight packing of amyloid fibrils. This packing is facilitated by the compatibility of the ridges and grooves on the a
Externí odkaz:
https://doaj.org/article/66201b7b33f74fcf9dc37cb4952362a3
Autor:
Yaman Arkun, Mert Gur
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29628 (2012)
A new method to develop low-energy folding routes for proteins is presented. The novel aspect of the proposed approach is the synergistic use of optimal control theory with Molecular Dynamics (MD). In the first step of the method, optimal control the
Externí odkaz:
https://doaj.org/article/819b57ffd9f5412abf1977cfbb4bb961
Autor:
Luke S. Ferro, Qianglin Fang, Lisa Eshun-Wilson, Jonathan Fernandes, Amanda Jack, Daniel P. Farrell, Mert Golcuk, Teun Huijben, Katelyn Costa, Mert Gur, Frank DiMaio, Eva Nogales, Ahmet Yildiz
Publikováno v:
Science (New York, N.Y.), vol 375, iss 6578
Microtubule (MT)–associated protein 7 (MAP7) is a required cofactor for kinesin-1–driven transport of intracellular cargoes. Using cryo–electron microscopy and single–molecule imaging, we investigated how MAP7 binds MTs and facilitates kinesi
Publikováno v:
Isı Bilimi ve Tekniği Dergisi. 41:265-276
The glutamine–glutamate/GABA cycle (GGC) is a sequence of events that provides replenishment of the neurotransmitter pool of glutamate in order to maintain neurotransmitter homeostasis. In the GGC, glutamate or GABA molecules are released from neur
Autor:
Elhan Taka, Mert Golcuk, Sema Zeynep Yilmaz, Ahmet Yildiz, Ceren Kilinc, Mert Gur, Umut Aktas
Publikováno v:
The Journal of Physical Chemistry. B
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects human cells upon binding of its spike (S) glycoproteins to ACE2 receptors and causes the coronavirus disease 2019 (COVID-19). Therapeutic approaches to prevent SARS-CoV-2 infection
Publikováno v:
Journal of chemical information and modeling. 62(10)
The Delta variant spreads more rapidly than previous variants of SARS-CoV-2. This variant comprises several mutations on the receptor-binding domain (RBD_Delta) of its spike (S) glycoprotein, which binds to the peptidase domain (PD) of angiotensin-co
Publikováno v:
Chemical Biology & Drug Design. 96:644-658
Behçet's disease is an inflammatory disorder of unknown etiology. Genetic tendency has an important role in its pathogenesis, and HLA-B51, a class I MHC antigen, has been recognized as the strongest susceptibility factor for Behçet's disease. Despi