Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Merryn Hall"'
Autor:
Zarnie Lwin, Eng-Siew Koh, Elizabeth H Barnes, Rosemary Harrup, Hui K Gan, Anna K Nowak, Craig Gedye, Sonia Yip, Benjamin Y Kong, Hao-Wen Sim, Jonathon Parkinson, Rosalind Jeffree, Elizabeth J Hovey, Merryn Hall, Emily Tu, Mark B Pinkham, Candace Carter, Anthony Dowling, John S Simes
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction Glioblastoma (GBM) is the most common malignant primary central nervous system cancer in adults. The objective of the Multi-Arm GlioblastoMa Australasia (MAGMA) trial is to test hypotheses in real world setting to improve survival of peo
Externí odkaz:
https://doaj.org/article/e3e6c47aec9f4f8cacc7e973ad7a136f
Autor:
Benjamin Y Kong, Hao-Wen Sim, Elizabeth H Barnes, Anna K Nowak, Elizabeth J Hovey, Rosalind Jeffree, Rosemary Harrup, Jonathon Parkinson, Hui K Gan, Mark B Pinkham, Sonia Yip, Merryn Hall, Emily Tu, Candace Carter, Eng-Siew Koh, Zarnie Lwin, Anthony Dowling, John S Simes, Craig Gedye
IntroductionGlioblastoma (GBM) is the most common malignant primary central nervous system cancer in adults. The objective of the Multi-Arm GlioblastoMa Australasia (MAGMA) trial is to test hypotheses in real world setting to improve survival of peop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97516e26ac47154b148b622c9b9fc25
Autor:
Mark Rosenthal, Michael E. Buckland, Mustafa Khasraw, Erik P. Sulman, Michael Back, Lauren Fisher, Matthew Foote, Sonia Yip, Eng-Siew Koh, Elizabeth H Barnes, Zarnie Lwin, Robyn Leonard, David M. Ashley, Kerrie L. McDonald, Helen Wheeler, Hao-Wen Sim, John Simes, Merryn Hall
Publikováno v:
Neuro-Oncology
BackgroundTemozolomide offers minimal benefit in patients with glioblastoma with unmethylated O6-methylguanine-DNA methyltransferase (MGMT) promoter status, hence, the need for novel therapies. This study evaluated whether veliparib, a brain-penetran
Autor:
Meera R Agar, Anna K Nowak, Elizabeth J Hovey, Elizabeth H Barnes, John Simes, Janette L Vardy, Helen R Wheeler, Benjamin Y Kong, Robyn Leonard, Merryn Hall, Evonne Tim, Desma Spyridopoulos, Hao-Wen Sim, Zarnie Lwin, Anthony Dowling, Rosemary Harrup, Ross Jennens, Ganessan Kichenadasse, Tracey Dunlop, Cecelia Gzell, Eng-Siew Koh
Publikováno v:
BMJ Supportive & Palliative Care. :spcare-2022
ObjectivesSymptoms of raised intracranial pressure (ICP) in recurrent high-grade glioma (HGG) generally require corticosteroid treatment, often causing toxicity with variable effects on ICP symptoms. Acetazolamide reduces ICP when used in other clini
Autor:
Benjamin Y Kong, Hao-Wen Sim, Anna K Nowak, Sonia Yip, Elizabeth H Barnes, Bryan W Day, Michael E Buckland, Roel Verhaak, Terrance Johns, Cleo Robinson, Marc A Thomas, Tindaro Giardina, Zarnie Lwin, Andrew M Scott, Jonathon Parkinson, Rosalind Jeffree, Richard de Abreu Lourenco, Elizabeth J Hovey, Lawrence M Cher, Ganessan Kichendasse, Mustafa Khasraw, Merryn Hall, Emily Tu, Benhur Amanuel, Eng-Siew Koh, Hui K Gan
Publikováno v:
BMJ Open
IntroductionGrades 2 and 3 gliomas (G2/3 gliomas), when combined, are the second largest group of malignant brain tumours in adults. The outcomes for G2/3 gliomas at progression approach the dismal outcomes for glioblastoma (GBM), yet there is a pauc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bb9b52e6cfac2ecb5ea43d40f9f14e
https://hdl.handle.net/10453/152950
https://hdl.handle.net/10453/152950
Autor:
Hao-Wen Sim, Zarnie Lwin, Elizabeth Barnes, Kerrie McDonald, Eng-Siew Koh, Mark Rosenthal, Matthew Foote, Michael Back, Helen Wheeler, Michael Buckland, Kyle Walsh, Lauren Fisher, Robyn Leonard, Merryn Hall, David Ashley, Sonia Yip, John Simes, Erik Sulman, Mustafa Khasraw
Publikováno v:
Neuro-Oncology. 24:vii81-vii81
BACKGROUND VERTU was a randomized phase II trial evaluating veliparib, a brain-penetrant PARP inhibitor, combined with radiotherapy and temozolomide, for patients with newly diagnosed MGMT-unmethylated glioblastoma. As part of planned correlative wor
Autor:
Hao-Wen Sim, Zarnie Lwin, Elizabeth Barnes, Kerrie McDonald, Sonia Yip, Roel Verhaak, Amy Heimberger, Merryn Hall, Matthew Wong, Ross Jennens, David Ashley, Mark Rosenthal, Elizabeth Hovey, Benjamin Ellingson, Annette Tognela, Hui Gan, Michael Back, Eng-Siew Koh, Anne Long, Katharine Cuff, Stephen Begbie, Craig Gedye, Anna Mislang, Hien Le, Margaret Johnson, Benjamin Kong, John Simes, Mustafa Khasraw
Publikováno v:
Neuro-Oncology. 24:vii65-vii65
BACKGROUND Nivolumab is a PD-1 inhibitor with known safety profile. An increase in mutations as we age is well documented in glioblastoma and other cancers. Higher mutational load is associated with increased response to nivolumab in extracranial mal
Autor:
Cleo Robinson, Terrance Grant Johns, Tindaro Giardina, Emily Tu, Marc A. Thomas, Rosalind L. Jeffree, Bryan W. Day, Anna K. Nowak, Mark Rosenthal, Elizabeth Hovey, Sonia Yip, Andrew M. Scott, Ganessan Kichendasse, Hao-Wen Sim, Eng-Siew Koh, Benjamin Y. Kong, Richard De Abreu Lourenco, Benhur Amanuel, Mustafa Khasraw, Roel G.W. Verhaak, Peter Lau, Zarnie Lwin, Lawrence Cher, James R. Whittle, Elizabeth H Barnes, Hui K Gan, Jonathon Parkinson, Michael E. Buckland, Merryn Hall
Publikováno v:
Neuro-Oncology. 23:vi106-vi107
BACKGROUND Grade 2 and 3 (G2/3) gliomas are the second largest group of brain tumors in adults. Although the prognosis for G2/3 gliomas at the time of relapse mirror those of glioblastoma, there are few trials in this space. METHODS LUMOS was a natio
Autor:
Rosemary Harrup, Anthony Dowling, Adam Cooper, Tracey Dunlop, John Simes, Elizabeth H Barnes, Katharine Cuff, Zarnie Lwin, Benjamin Y. Kong, Elizabeth Hovey, Hui K Gan, Merryn Hall, Anna K. Nowak, Rosalind L. Jeffree, Emily Tu, Peter Lau, Sonia Yip, Diana Andrew, Eng-Siew Koh, Eric Khoo, Anthony Linton, Jonathon Parkinson, Craig Gedye, Hao-Wen Sim
Publikováno v:
Neuro-Oncology. 23:vi193-vi194
BACKGROUND Survival outcomes for patients with newly diagnosed glioblastoma have not changed significantly since the introduction of concurrent temozolomide with post-surgical radiation followed by adjuvant temozolomide. METHODS Multi-Arm Glioblastom
Autor:
John Simes, Tracey Dunlop, Anthony Dowling, Merryn Hall, Desma Spyridopoulos, Rosemary Harrup, Robyn Leonard, Meera Agar, Elizabeth H Barnes, C. Gzell, Elizabeth Hovey, Eng-Siew Koh, Ganessan Kichenadasse, Evonne Tim, Zarnie Lwin, Ross Jennens, Hao-Wen Sim, Janette L. Vardy, Helen Wheeler, Anna K. Nowak
Publikováno v:
Neuro Oncol
INTRODUCTION Symptoms of raised intracranial pressure (ICP) in recurrent or progressive high-grade glioma (HGG) generally require corticosteroid treatment, often causing toxicity with variable effects on reversing ICP symptoms. Acetazolamide reduces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8b8951a9c2cd77586df6fdfc218987
https://hdl.handle.net/10453/148429
https://hdl.handle.net/10453/148429