Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Merryn Brettle"'
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
Merryn Brettle, Holly Stefen, Aleksandra Djordjevic, Sandra Y. Y. Fok, Josephine W. Chan, Annika van Hummel, Julia van der Hoven, Magdalena Przybyla, Alexander Volkerling, Yazi D. Ke, Fabien Delerue, Lars M. Ittner, Thomas Fath
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with limited treatment and no cure. Mutations in profilin 1 were identified as a cause of familial ALS (fALS) in 2012. We investigated the functional impact of mutant prof
Externí odkaz:
https://doaj.org/article/3c0e270200b2444cb6a7451db65ce18f
Autor:
Shrujna Patel, Sandra Y Y Fok, Holly Stefen, Tamara Tomanić, Esmeralda Parić, Rosanna Herold, Merryn Brettle, Aleksandra Djordjevic, Thomas Fath
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187979 (2017)
Genetically encoded filamentous actin probes, Lifeact, Utrophin and F-tractin, are used as tools to label the actin cytoskeleton. Recent evidence in several different cell types indicates that these probes can cause changes in filamentous actin dynam
Externí odkaz:
https://doaj.org/article/8daefc42a1734114af745acf474d542a
Autor:
Kate Montgomery, Timothy J. Williams, Merryn Brettle, Jonathan F. Berengut, Eden Zhang, Julian Zaugg, Philip Hugenholtz, Belinda C. Ferrari
Publikováno v:
Environmental Microbiology. 24:4491-4491
Autor:
Kate Montgomery, Timothy J. Williams, Merryn Brettle, Jonathan F. Berengut, Angelique E. Ray, Eden Zhang, Julian Zaugg, Philip Hugenholtz, Belinda C. Ferrari
Publikováno v:
Environmental microbiologyReferences. 23(8)
Candidatus Dormibacterota is an uncultured bacterial phylum found predominantly in soil that is present in high abundances within cold desert soils. Here, we interrogate nine metagenome-assembled genomes (MAGs), including six new MAGs derived from so
Autor:
Majid Ebrahimi Warkiani, Merryn Brettle, Tracie Barber, Nicodemus Tedla, Sandra Fok, Holly Stefen, Thomas Fath, Alexandra K. Suchowerska, Amin Hassanzadeh-Barforoushi
Publikováno v:
Cellular and Molecular Neurobiology. 38:1557-1563
Overcoming neurite inhibition is integral for restoring neuronal connectivity after CNS injury. Actin dynamics are critical for neurite growth cone formation and extension. The tropomyosin family of proteins is a regarded as master regulator of actin
Autor:
Thomas Fath, Holly Stefen, Bei Jun Chen, Alexandra K. Suchowerska, Jennifer Kuschelewski, Michael Janitz, Merryn Brettle, Peter W. Gunning
Publikováno v:
FEBS Open Bio
Tropomyosins, a family of actin-associated proteins, bestow actin filaments with distinct biochemical and physical properties which are important for determining cell shape and regulating many cellular processes in eukaryotic cells. Here, we used RNA
Autor:
Merryn Brettle, Timothy A. Couttas, Anthony S. Don, Yanfei Qi, Holly Stefen, Sean J. Humphrey, Thomas Fath, Collin Tran, Benjamin Heng, Gilles J. Guillemin, Jonathan D. Teo
Publikováno v:
Journal of neurochemistryREFERENCES. 153(2)
Sphingosine 1-phosphate (S1P) is an essential lipid metabolite that signals through a family of five G protein-coupled receptors, S1PR1-S1PR5, to regulate cell physiology. The multiple sclerosis drug Fingolimod (FTY720) is a potent S1P receptor agoni
Autor:
Rosanna Herold, Thomas Fath, Shrujna Patel, Merryn Brettle, Esmeralda Paric, Tamara Tomanic, Sandra Fok, Aleksandra Djordjevic, Holly Stefen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0187979 (2017)
PLoS ONE, Vol 12, Iss 11, p e0187979 (2017)
Genetically encoded filamentous actin probes, Lifeact, Utrophin and F-tractin, are used as tools to label the actin cytoskeleton. Recent evidence in several different cell types indicates that these probes can cause changes in filamentous actin dynam
Autor:
Peter W. Gunning, Galina Schevzov, Anne Poljak, Thomas Fath, Edna C. Hardeman, Nikki M. Curthoys, Melissa Desouza, Merryn Brettle, Hannah Freittag, Andrea Connor, Amelia Hall
Publikováno v:
Molecular and Cellular Neuroscience. 58:11-21
Background The actin cytoskeleton is critically involved in the regulation of neurite outgrowth. Results The actin cytoskeleton-associated protein tropomyosin induces neurite outgrowth in B35 neuroblastoma cells and regulates neurite branching in an