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pro vyhledávání: '"Merrill E. Asp"'
Autor:
Merrill E. Asp, Minh-Tri Ho Thanh, Subarna Dutta, Jessica A. Comstock, Roy D. Welch, Alison E. Patteson
Publikováno v:
Biophysics Reviews. 4
The central hypothesis of the genotype–phenotype relationship is that the phenotype of a developing organism (i.e., its set of observable attributes) depends on its genome and the environment. However, as we learn more about the genetics and bioche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d79b3c6e881f19780ad09c20e421fd53
https://doi.org/10.1063/5.0142121
https://doi.org/10.1063/5.0142121
The genotype-to-phenotype problem (G2P) for multicellular development asks how genetic inputs control collective phenotypic outputs. It is a difficult problem even to observe. On the genotype side, the phenotypic impact of mutation is often subtle du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ad73b07a4beea47dbddb6c826fdcf5
https://doi.org/10.1101/2023.02.26.530117
https://doi.org/10.1101/2023.02.26.530117
Autor:
Jessica A. Comstock, Merrill E. Asp, Fatmagül Bahar, Isabella Lee, Alison E. Patteson, Roy D. Welch
Robustness to the impact of mutation can mitigate phenotypes that have the potential to inform gene function. This robustness is often encoded into the genome through gene duplication, among other mechanisms. Duplication is a source of structurally s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2c0cea819509814ca8b5685e7ae0fca
https://doi.org/10.1101/2022.07.25.501402
https://doi.org/10.1101/2022.07.25.501402
Autor:
Merrill E Asp, Minh-Tri Ho Thanh, Danielle A Germann, Robert J Carroll, Alana Franceski, Roy D Welch, Arvind Gopinath, Alison E Patteson
Publikováno v:
PNAS Nexus. 1
The ability of bacteria to colonize and grow on different surfaces is an essential process for biofilm development. Here, we report the use of synthetic hydrogels with tunable stiffness and porosity to assess physical effects of the substrate on biof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a869dcca0d9a2bd91dda00eec80c5d70
https://doi.org/10.1093/pnasnexus/pgac025
https://doi.org/10.1093/pnasnexus/pgac025
Publikováno v:
Appl Phys Rev
Living systems are composed of molecules that are synthesized by cells that use energy sources within their surroundings to create fascinating materials that have mechanical properties optimized for their biological function. Their functionality is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e94be73677400c3de73e889a987f0e3
https://doi.org/10.1063/5.0071648
https://doi.org/10.1063/5.0071648