Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.

Autor: Self WH; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Semler MW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Leither LM; Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, Utah.; University of Utah, Salt Lake City., Casey JD; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Angus DC; Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Brower RG; Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Chang SY; Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine at UCLA, Ronald Reagan-UCLA Medical Center, Los Angeles, California., Collins SP; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Eppensteiner JC; Department of Surgery, Duke University, Durham, North Carolina., Filbin MR; Department of Emergency Medicine, Massachusetts General Hospital, Boston., Files DC; Section of Pulmonary, Critical Care, Allergy and Immunologic Disease, Department of Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina., Gibbs KW; Section of Pulmonary, Critical Care, Allergy and Immunologic Disease, Department of Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina., Ginde AA; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora., Gong MN; Division of Epidemiology and Population Health, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York., Harrell FE Jr; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee., Hayden DL; Department of Medicine, Massachusetts General Hospital, Boston., Hough CL; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Oregon Health and Science University School of Medicine, Portland., Johnson NJ; Department of Emergency Medicine and Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle., Khan A; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Oregon Health and Science University School of Medicine, Portland., Lindsell CJ; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee., Matthay MA; Cardiovascular Research Institute, Departments of Medicine and Anesthesia, University of California, San Francisco., Moss M; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora., Park PK; Department of Surgery, University of Michigan, Ann Arbor., Rice TW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Robinson BRH; Department of Surgery, University of Washington, Seattle., Schoenfeld DA; Department of Medicine, Massachusetts General Hospital, Boston., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Steingrub JS; Department of Medicine, University of Massachusetts Medical School-Baystate, Springfield., Ulysse CA; Department of Medicine, Massachusetts General Hospital, Boston., Weissman A; Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Yealy DM; Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Thompson BT; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Boston., Brown SM; Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, Utah.; University of Utah, Salt Lake City., Steingrub J, Smithline H, Tiru B, Tidswell M, Kozikowski L, Thornton-Thompson S, De Souza L, Hou P, Baron R, Massaro A, Aisiku I, Fredenburgh L, Seethala R, Johnsky L, Riker R, Seder D, May T, Baumann M, Eldridge A, Lord C, Shapiro N, Talmor D, O’Mara T, Kirk C, Harrison K, Kurt L, Schermerhorn M, Banner-Goodspeed V, Boyle K, Dubosh N, Filbin M, Hibbert K, Parry B, Lavin-Parsons K, Pulido N, Lilley B, Lodenstein C, Margolin J, Brait K, Jones A, Galbraith J, Peacock R, Nandi U, Wachs T, Matthay M, Liu K, Kangelaris K, Wang R, Calfee C, Yee K, Hendey G, Chang S, Lim G, Qadir N, Tam A, Beutler R, Levitt J, Wilson J, Rogers A, Vojnik R, Roque J, Albertson T, Chenoweth J, Adams J, Pearson S, Juarez M, Almasri E, Fayed M, Hughes A, Hillard S, Huebinger R, Wang H, Vidales E, Patel B, Ginde A, Moss M, Baduashvili A, McKeehan J, Finck L, Higgins C, Howell M, Douglas I, Haukoos J, Hiller T, Lyle C, Cupelo A, Caruso E, Camacho C, Gravitz S, Finigan J, Griesmer C, Park P, Hyzy R, Nelson K, McDonough K, Olbrich N, Williams M, Kapoor R, Nash J, Willig M, Ford H, Gardner-Gray J, Ramesh M, Moses M, Ng Gong M, Aboodi M, Asghar A, Amosu O, Torres M, Kaur S, Chen JT, Hope A, Lopez B, Rosales K, Young You J, Mosier J, Hypes C, Natt B, Borg B, Salvagio Campbell E, Hite RD, Hudock K, Cresie A, Alhasan F, Gomez-Arroyo J, Duggal A, Mehkri O, Hastings A, Sahoo D, Abi Fadel F, Gole S, Shaner V, Wimer A, Meli Y, King A, Terndrup T, Exline M, Pannu S, Robart E, Karow S, Hough C, Robinson B, Johnson N, Henning D, Campo M, Gundel S, Seghal S, Katsandres S, Dean S, Khan A, Krol O, Jouzestani M, Huynh P, Weissman A, Yealy D, Scholl D, Adams P, McVerry B, Huang D, Angus D, Schooler J, Moore S, Files C, Miller C, Gibbs K, LaRose M, Flores L, Koehler L, Morse C, Sanders J, Langford C, Nanney K, MdalaGausi M, Yeboah P, Morris P, Sturgill J, Seif S, Cassity E, Dhar S, de Wit M, Mason J, Goodwin A, Hall G, Grady A, Chamberlain A, Brown S, Bledsoe J, Leither L, Peltan I, Starr N, Fergus M, Aston V, Montgomery Q, Smith R, Merrill M, Brown K, Armbruster B, Harris E, Middleton E, Paine R, Johnson S, Barrios M, Eppensteiner J, Limkakeng A, McGowan L, Porter T, Bouffler A, Leahy JC, deBoisblanc B, Lammi M, Happel K, Lauto P, Self W, Casey J, Semler M, Collins S, Harrell F, Lindsell C, Rice T, Stubblefield W, Gray C, Johnson J, Roth M, Hays M, Torr D, Zakaria A, Schoenfeld D, Thompson T, Hayden D, Ringwood N, Oldmixon C, Ulysse C, Morse R, Muzikansky A, Fitzgerald L, Whitaker S, Lagakos A, Brower R, Reineck L, Aggarwal N, Bienstock K, Freemer M, Maclawiw M, Weinmann G, Morrison L, Gillespie M, Kryscio R, Brodie D, Zareba W, Rompalo A, Boeckh M, Parsons P, Christie J, Hall J, Horton N, Zoloth L, Dickert N, Diercks D

Publikováno v: JAMA [JAMA] 2020 Dec 01; Vol. 324 (21), pp. 2165-2176.