Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Merril C. Curry"'
Publikováno v:
Biochemical and Biophysical Research Communications. 478:1792-1797
PMCA2 overexpression in some breast cancers suggests that this calcium pump isoform may play a role in breast pathophysiology. To investigate PMCA2 as a potential drug target for breast cancer therapy, we assessed the functional consequence of PMCA2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db359e84f902c87c15753491821d6e4
https://doi.org/10.1016/j.bbrc.2016.09.030
https://doi.org/10.1016/j.bbrc.2016.09.030
Autor:
Gregory R. Monteith, Jean-Thomas Pierson, Sarah J. Roberts-Thomson, Merril C. Curry, Michael J. Gidley, Ralf G. Dietzgen, Paul N. Shaw, Van L. T. Hoang
Publikováno v:
Food Science and Biotechnology. 24:265-271
Bioactivities of peel and flesh extracts of 3 genetically diverse mango (Mangifera indica L.) varieties were studied. Nam Doc Mai peel extracts, containing the largest amounts of polyphenols, were associated with an effect on MCF-7 viable cell number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a25aafdf2c015b4acb82aeaa72210c8a
https://doi.org/10.1007/s10068-015-0035-x
https://doi.org/10.1007/s10068-015-0035-x
Autor:
Merril C. Curry
Plasma membrane calcium (Ca2+) ATPase isoforms (PMCA1-4) extrude cytoplasmic free calcium([Ca2+]CYT) and maintain low intracellular Ca2+ levels. Because [Ca2+]CYT increases can trigger celldeath, inhibition of PMCA-mediated Ca2+ efflux has been propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989816e1a673e1bda4c0fafadc184aa4
https://doi.org/10.14264/uql.2017.418
https://doi.org/10.14264/uql.2017.418
Autor:
Merril C. Curry, Sarah J. Roberts-Thomson, Amelia A. Peters, Paraic A. Kenny, Gregory R. Monteith
Publikováno v:
Biochemical and Biophysical Research Communications. 434:695-700
The mitochondrial calcium uniporter (MCU) transports free ionic Ca(2+) into the mitochondrial matrix. We assessed MCU expression in clinical breast cancer samples using microarray analysis and the consequences of MCU silencing in a breast cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0750db5141c11e6613c2557a88491d7
https://doi.org/10.1016/j.bbrc.2013.04.015
https://doi.org/10.1016/j.bbrc.2013.04.015
Publikováno v:
Journal of Biological Chemistry. 287:28598-28608
Plasma membrane calcium ATPases (PMCAs) actively extrude Ca(2+) from the cell and are essential components in maintaining intracellular Ca(2+) homeostasis. There are four PMCA isoforms (PMCA1-4), and alternative splicing of the PMCA genes creates a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3e05c78cd06ba39adebecce32b85e5
https://doi.org/10.1074/jbc.m112.364737
https://doi.org/10.1074/jbc.m112.364737
Autor:
Gregory R. Monteith, Michael J. G. Milevskiy, Sarah J. Roberts-Thomson, Sunil R. Lakhani, Merril C. Curry, Lynne Reid, Melissa A. Brown, Leonard Da Silva, Jodi M. Saunus, Eloise Dray, Chanel E. Smart, Amelia A. Peters, Daneth L. Marcial, Wei C. Lee
Publikováno v:
Scientific Reports
Regulation of Ca2+ transport is vital in physiological processes, including lactation, proliferation and apoptosis. The plasmalemmal Ca2+ pump isoform 2 (PMCA2) a calcium ion efflux pump, was the first protein identified to be crucial in the transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9940c96abc1c1c58735607d49e5bb2
https://pubmed.ncbi.nlm.nih.gov/27148852
https://pubmed.ncbi.nlm.nih.gov/27148852
Publikováno v:
BioFactors (Oxford, England). 37(3)
The plasma membrane calcium ATPases (PMCAs) are vital regulators of basal Ca(2+) and shape the nature of intracellular free Ca(2+) transients after cellular stimuli and are thus regulators of a plethora of cellular processes. Studies spanning many ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8981b86619b35179ab11d7d4ff7b5b7f
https://pubmed.ncbi.nlm.nih.gov/21674637
https://pubmed.ncbi.nlm.nih.gov/21674637
Publikováno v:
World journal of biological chemistry. 1(8)
Alterations in calcium signaling and/or the expression of calcium pumps and channels are an increasingly recognized property of some cancer cells. Alterations in the expression of plasma membrane calcium ATPase (PMCA) isoforms have been reported in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff95bd766e5f90f33bda9e81956b09e
https://pubmed.ncbi.nlm.nih.gov/21537481
https://pubmed.ncbi.nlm.nih.gov/21537481
Publikováno v:
ChemInform. 37
The use of chiral secondary amines containing only one branched substituent has been shown to give optimal yields and stereoselectivities in the preparation of α-amino acids using the Petasis reaction. While the use of chiral primary amines generall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6240e3b9eb938de1ca8de346817eb2
https://doi.org/10.1002/chin.200617060
https://doi.org/10.1002/chin.200617060
Publikováno v:
Molecular Cancer Therapeutics. 10:A30-A30
Intracellular calcium is a vital cell signaling molecule that can influence a myriad of important cellular functions, including those deregulated in the cancer cell. Consequently Ca2+ levels within the cell must be precisely controlled. Amongst the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d941fb6f0dc120db8375396073db1834
https://doi.org/10.1158/1535-7163.targ-11-a30
https://doi.org/10.1158/1535-7163.targ-11-a30