Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Merridee A Wouters"'
Autor:
Romaric Bouveret, Ashley J Waardenberg, Nicole Schonrock, Mirana Ramialison, Tram Doan, Danielle de Jong, Antoine Bondue, Gurpreet Kaur, Stephanie Mohamed, Hananeh Fonoudi, Chiann-mun Chen, Merridee A Wouters, Shoumo Bhattacharya, Nicolas Plachta, Sally L Dunwoodie, Gavin Chapman, Cédric Blanpain, Richard P Harvey
Publikováno v:
eLife, Vol 4 (2015)
We take a functional genomics approach to congenital heart disease mechanism. We used DamID to establish a robust set of target genes for NKX2-5 wild type and disease associated NKX2-5 mutations to model loss-of-function in gene regulatory networks.
Externí odkaz:
https://doaj.org/article/4af17a74739c4c6ca56af49e332c7b67
Autor:
Rebecca C. Poulos, Peter G. Hains, Rohan Shah, Natasha Lucas, Dylan Xavier, Srikanth S. Manda, Asim Anees, Jennifer M. S. Koh, Sadia Mahboob, Max Wittman, Steven G. Williams, Erin K. Sykes, Michael Hecker, Michael Dausmann, Merridee A. Wouters, Keith Ashman, Jean Yang, Peter J. Wild, Anna deFazio, Rosemary L. Balleine, Brett Tully, Ruedi Aebersold, Terence P. Speed, Yansheng Liu, Roger R. Reddel, Phillip J. Robinson, Qing Zhong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Clinical proteomics critically depends on the ability to acquire highly reproducible data over an extended period of time. Here, the authors assess reproducibility over four months across different mass spectrometers and develop a computational appro
Externí odkaz:
https://doaj.org/article/f31d48fe5cbd4e4fb32261099a109959
Autor:
Frederick Masson, Matthias Ernst, John M. Mariadason, Oliver M. Sieber, Tracy L. Putoczki, Mercedes Davalos-Salas, Paul M. Nguyen, Dmitri Mouradov, David Baloyan, Merridee A. Wouters, Christine Dijkstra, Moritz F. Eissmann
Fig S3. St2 is not expressed by Lgr5+ stem cells within the colon.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d612ab0e6c2862f5a1db3fed867bd2b
https://doi.org/10.1158/2326-6066.22539700.v1
https://doi.org/10.1158/2326-6066.22539700.v1
Autor:
Frederick Masson, Matthias Ernst, John M. Mariadason, Oliver M. Sieber, Tracy L. Putoczki, Mercedes Davalos-Salas, Paul M. Nguyen, Dmitri Mouradov, David Baloyan, Merridee A. Wouters, Christine Dijkstra, Moritz F. Eissmann
Suppl Table 1. Oligonucleotide Sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ee4b79dd43569a7ab41ca76d85be5b
https://doi.org/10.1158/2326-6066.22539688
https://doi.org/10.1158/2326-6066.22539688
Autor:
Sara Ballouz, Jason Y. Liu, Martin Oti, Bruno Gaeta, Diane Fatkin, Melanie Bahlo, Merridee A. Wouters
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 2, Iss 1, Pp 44-57 (2014)
Abstract Current single‐locus‐based analyses and candidate disease gene prediction methodologies used in genome‐wide association studies (GWAS) do not capitalize on the wealth of the underlying genetic data, nor functional data available from m
Externí odkaz:
https://doaj.org/article/8c07cdbe574c44818d8c501b2e69ce70
Publikováno v:
Protein Science. 28:239-256
Some disulfide bonds perform important structural roles in proteins, but another group has functional roles via redox reactions. Forbidden disulfides are stressed disulfides found in recognizable protein contexts, which currently constitute more than
Autor:
Keith Ashman, Asim Anees, Terence P. Speed, Erin K. Sykes, Roger R. Reddel, Yansheng Liu, Jennifer M. S. Koh, Jean Yang, Merridee A. Wouters, Steven G. Williams, Peter J. Wild, Anna deFazio, Natasha Lucas, Max Wittman, Dylan Xavier, Michael Hecker, Sadia Mahboob, Michael Dausmann, Ruedi Aebersold, Peter G. Hains, Brett Tully, Rohan Shah, Phillip J. Robinson, Qing Zhong, Rosemary L. Balleine, Srikanth S. Manda, Rebecca C. Poulos
Publikováno v:
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop computational methods for improving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72057dd71a63badf92c2a0858853f64
https://hdl.handle.net/20.500.11850/430457
https://hdl.handle.net/20.500.11850/430457
Autor:
Sharon Tran, Nadia J. Kershaw, Neil D. Young, Tiffany J Harris, Brian J. Smith, Erinna F. Lee, Merridee A. Wouters, Tatiana P. Soares da Costa, W. Douglas Fairlie, Robin B. Gasser, Marco Evangelista
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology
Early studies of the free-living nematode C. elegans informed us how BCL-2-regulated apoptosis in humans is regulated. However, subsequent studies showed C. elegans apoptosis has several unique features compared with human apoptosis. To date, there h
Autor:
Tamsyn M. Crowley, Mani P Grover, Kaavya A Mohanasundaram, Andrzej Goscinski, Merridee A. Wouters
Publikováno v:
Human Mutation. 38:1378-1393
We assessed the impact of disease mutations (DMs) versus polymorphisms (PYs) in coiled-coil (CC) domains in UniProt by modeling the structural and functional impact of variants in silico with the CC prediction program Multicoil. The structural impact
Autor:
Yalin, Li, Weidong, Wang, Tao, Wang, Merridee A, Wouters, Yue, Yin, Zhen, Jiao, Lixia, Ma, Fengqiu, Zhang
Publikováno v:
Radiation research. 191(2)
MicroRNAs (miRNAs) are a non-coding regulatory RNAs that play significant roles in plant growth and development, especially in the stress response. Low-energy ion radiation, a type of environmental stress, can cause multiple biological effects. To un