The impact of early life exposure to Plasmodium falciparum on the development of naturally acquired immunity to malaria in young Malawian children

Autor: Priyanka Barua, James G. Beeson, Kenneth Maleta, Per Ashorn, Stephen J. Rogerson

Publikováno v: Malaria Journal, Vol 18, Iss 1, Pp 1-12 (2019)

Abstract Background Antibodies targeting malaria blood-stage antigens are important targets of naturally acquired immunity, and may act as valuable biomarkers of malaria exposure. Methods Six-hundred and one young Malawian children from a randomized

Externí odkaz: https://doaj.org/article/0d8130bc7f1f42c39adf6cabba87ee8f

Effect of nutrient supplementation on the acquisition of humoral immunity to Plasmodium falciparum in young Malawian children

Autor: Priyanka Barua, Upeksha P. Chandrasiri, James G. Beeson, Kathryn G. Dewey, Kenneth Maleta, Per Ashorn, Stephen J. Rogerson

Publikováno v: Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)

Abstract Background There is evidence that suggests that undernutrition has a detrimental effect on malarial immunity in children. The aim of the study was to discover whether nutrient supplementation improved development of malarial antibody immunit

Externí odkaz: https://doaj.org/article/8402150f8fa14b75ac71c9f6c0a57b97

Comparative recognition by human IgG antibodies of recombinant proteins representing three asexual erythrocytic stage vaccine candidates of Plasmodium vivax

Autor: Mayara B Barbedo, Ricardo Ricci, Maria Carolina S Jimenez, Maristela G Cunha, Syed S Yazdani, Chetan E Chitnis, Mauricio M Rodrigues, Irene S Soares

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 102, Iss 3, Pp 335-340 (2007)

In previous immuno-epidemiological studies of the naturally acquired antibody responses to merozoite surface protein-1 (MSP-1) of Plasmodium vivax, we had evidence that the responses to distinct erythrocytic stage antigens could be differentially reg

Externí odkaz: https://doaj.org/article/ad787abe30e94f8ab6f7697f993d20e1

Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

Autor: Michael Theisen, Régis Wendpayangde Tiendrebeogo, Ikhlaq Hussain Kana, Subhash C. Singh, Susheel K. Singh, Bishwanath Kumar Chourasia

Publikováno v: Microbial Cell Factories, Vol 17, Iss 1, Pp 1-13 (2018)
Singh, S K, Tiendrebeogo, R W, Chourasia, B K, Kana, I H, Singh, S & Theisen, M 2018, ' Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum ', Microbial Cell Factories, vol. 17, 55 . https://doi.org/10.1186/s12934-018-0902-2
Microbial Cell Factories

Background The production of recombinant proteins with proper conformation, appropriate post-translational modifications in an easily scalable and cost-effective system is challenging. Lactococcus lactis has recently been identified as an efficient G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b41abfd9ae555c1c761d5bb884c5e7b
http://link.springer.com/article/10.1186/s12934-018-0902-2

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