Collagen II enrichment through scAAV6-RNAi-mediated inhibition of matrix-metalloproteinases 3 and 13 in degenerative nucleus-pulposus cells degenerative disc disease and biological treatment strategies.

Autor: Mern DS; Department of Neurosurgery, Medical University of Innsbruck, Innsbruck, Austria., Thomé C; Department of Neurosurgery, Medical University of Innsbruck, Innsbruck, Austria.

Publikováno v: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2024 Sep 02; Vol. 249, pp. 10048. Date of Electronic Publication: 2024 Sep 02 (Print Publication: 2024).

Matcha Green Tea Powder does not Prevent Diet-Induced Arteriosclerosis in New Zealand White Rabbits Due to Impaired Reverse Cholesterol Transport.

Autor: Hunjadi M; Department of Internal Medicine, Medical University of Innsbruck, Innsbruck, Austria., Sieder C; Department of Internal Medicine, Medical University of Innsbruck, Innsbruck, Austria., Beierfuß A; Central Laboratory Animal Facility, Medical University of Innsbruck, Innsbruck, Austria., Kremser C; Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria., Moriggl B; Division Clinical and Functional Anatomy, Medical University of Innsbruck, Innsbruck, Austria., Welte R; Clinical Pharmacokinetics Unit, Division of Intensive Care and Emergency Medicine, Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria., Kastner C; Department of Internal Medicine, Medical University of Innsbruck, Innsbruck, Austria., Mern DS; Department of Neurosurgery, Medical University of Innsbruck, Innsbruck, Austria., Ritsch A; Department of Internal Medicine, Medical University of Innsbruck, Innsbruck, Austria.

Publikováno v: Molecular nutrition & food research [Mol Nutr Food Res] 2021 Oct; Vol. 65 (20), pp. e2100371. Date of Electronic Publication: 2021 Aug 27.

APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix.

Autor: Beierfuß A; Laboratory Animal Facility, Medical University of Innsbruck, Innsbruck, Austria., Hunjadi M; Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria., Ritsch A; Department of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria., Kremser C; Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria., Thomé C; Department of Neurosurgery, Medical University of Innsbruck, Innsbruck, Austria., Mern DS; Department of Neurosurgery, Medical University of Innsbruck, Innsbruck, Austria.

Publikováno v: PloS one [PLoS One] 2019 Nov 21; Vol. 14 (11), pp. e0225527. Date of Electronic Publication: 2019 Nov 21 (Print Publication: 2019).

Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders.

Autor: Mern DS; Department of Neurosurgery, Innsbruck Medical University, Innsbruck, Austria., Tschugg A; Department of Neurosurgery, Innsbruck Medical University, Innsbruck, Austria., Hartmann S; Department of Neurosurgery, Innsbruck Medical University, Innsbruck, Austria., Thomé C; Department of Neurosurgery, Innsbruck Medical University, Innsbruck, Austria.

Publikováno v: PloS one [PLoS One] 2017 Feb 16; Vol. 12 (2), pp. e0172181. Date of Electronic Publication: 2017 Feb 16 (Print Publication: 2017).

Enhancing tissue repair in annulus fibrosus defects of the intervertebral disc: analysis of a bio-integrative annulus implant in an in-vivo ovine model.

Autor: Hegewald AA; Department of Neurosurgery, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany; Department of Neurosurgery, Innsbruck Medical University, Innsbruck, Austria., Medved F, Feng D, Tsagogiorgas C, Beierfuß A, Schindler GA, Trunk M, Kaps C, Mern DS, Thomé C

Publikováno v: Journal of tissue engineering and regenerative medicine [J Tissue Eng Regen Med] 2015 Apr; Vol. 9 (4), pp. 405-14. Date of Electronic Publication: 2013 Nov 12.