Probing the quality control mechanism of the Escherichia coli twin-arginine translocase with folding variants of a de novo -designed heme protein.

Autor: Sutherland GA; From the Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom., Grayson KJ; From the Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom., Adams NBP; From the Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom., Mermans DMJ; the School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom., Jones AS; the School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom., Robertson AJ; From the Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom., Auman DB; the Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Brindley AA; From the Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom., Sterpone F; the Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 75005 Paris, France, and., Tuffery P; INSERM U973, Université Paris Diderot, Sorbonne Paris Cité, 75013 Paris, France., Derreumaux P; the Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, 75005 Paris, France, and., Dutton PL; the Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Robinson C; the School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom., Hitchcock A; From the Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom., Hunter CN; From the Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, United Kingdom, c.n.hunter@sheffield.ac.uk.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2018 May 04; Vol. 293 (18), pp. 6672-6681. Date of Electronic Publication: 2018 Mar 20.