Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mermagya Dhakal"'
Autor:
Mindy M. Miller, Adam A. Zaghouani, John C. Hardaway, Jason A. Cascio, Linda M. Rowland, Fatma Betul Guloglu, Michael P. Sherman, Xiaoxiao Wan, Christine M. Hoeman, Mermagya Dhakal, Habib Zaghouani
Publikováno v:
European Journal of Immunology. 44:842-855
In this study, we examined the role IL-13 receptor alpha 1 (IL-13Rα1) plays in macrophage differentiation and function. The findings indicate that IL-13Rα1 is expressed on the M2 but not on the M1 subset of macrophages and specifically heterodimeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9859b9f54882438d78a2019a1d8e4dae
https://doi.org/10.1002/eji.201343755
https://doi.org/10.1002/eji.201343755
Autor:
Mermagya Dhakal, Jason A. Cascio, Xiaoxiao Wan, Weirong Chen, Marie-Therese Khairallah, Mindy M. Miller, Linda M. Rowland, Habib Zaghouani
Publikováno v:
Journal of Neuroimmunology. 266:49-55
F 1 (SJL/J × C57BL/6) mice with MOG35–55-induced EAE recover from disease when treated with Ig-MOG carrying MOG35–55 peptide. However, Ig-PLP1, carrying PLP139–151, induced reduction of anti-MOG antibodies and exacerbated EAE. Herein, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e236df61acbeb5831fc1d5e771f34e9c
https://doi.org/10.1016/j.jneuroim.2013.09.022
https://doi.org/10.1016/j.jneuroim.2013.09.022
Autor:
Jason A. Cascio, Jason S. Ellis, Mermagya Dhakal, Xiaoxiao Wan, Christine M. Hoeman, F. Betul Guloglu, Habib Zaghouani
Publikováno v:
The Journal of Immunology. 191:1126-1135
The events controlling the transition of T cells from effector to memory remain largely undefined. Many models have been put forth to account for the origin of memory precursors, but for CD4 T cells initial studies reported that memory T cells derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a854202190919510780cf06596db369d
https://doi.org/10.4049/jimmunol.1202262
https://doi.org/10.4049/jimmunol.1202262
Autor:
Xiaoxiao Wan, Christine M. Hoeman, Sarah Zaghouani, Amie M. VanMorlan, Jason A. Cascio, Mermagya Dhakal, F. Betul Guloglu, Habib Zaghouani, Linda M. Rowland
Publikováno v:
Diabetes
Immune modulation of pancreatic inflammation induces recovery from type 1 diabetes (T1D), but remission was not durable, perhaps because of an inability to sustain the formation and function of new pancreatic β-cells. We have previously shown that I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b828b9be3754de96e28ab429e0a7a9ef
https://doi.org/10.2337/db12-1281
https://doi.org/10.2337/db12-1281
Autor:
Mermagya Dhakal, Sarah Zaghouani, Xiaoxiao Wan, Marie Therese Khairallah, Weirong Chen, Habib Zaghouani, Rohit D. Divekar, Linda M. Rowland, Cara L. Haymaker, Jason A. Cascio
Publikováno v:
The Journal of Immunology. 190:6004-6014
Dendritic cells (DCs) have been shown to play a major role in oral tolerance, and this function has been associated with their ability to produce anti-inflammatory cytokines and to induce suppressive regulatory T cells. In this study, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a6cab76d13e0243b690880be75084c
https://doi.org/10.4049/jimmunol.1203552
https://doi.org/10.4049/jimmunol.1203552
Autor:
Danielle M. Tartar, Jason A. Cascio, F. Betul Guloglu, Habib Zaghouani, Xiaoxiao Wan, Christine M. Hoeman, Amie M. VanMorlan, Jason S. Ellis, Mermagya Dhakal, Seung Hi Yahng, Cara L. Haymaker
Publikováno v:
The Journal of Immunology. 185:3149-3157
The role APCs play in the transition of T cells from effector to memory remains largely undefined. This is likely due to the low frequency at which long-lived T cells arise, which hinders analysis of the events involved in memory development. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b31eb67b897db315e818d56bf58c3ea
https://doi.org/10.4049/jimmunol.1000810
https://doi.org/10.4049/jimmunol.1000810
Autor:
Mermagya Dhakal, Habib Zaghouani, Mohamed Oukka, Amie M. VanMorlan, Cara L. Haymaker, Renu Jain, F. Betul Guloglu, Xiaoxiao Wan, Jason A. Cascio, Christine M. Hoeman, Jason S. Ellis, Danielle M. Tartar
Publikováno v:
The Journal of Immunology. 184:3377-3385
Recently, traces of double-positive FoxP3+RORγt+ T cells were identified and viewed as dual programming differentiation intermediates geared toward development into T regulatory or Th17 cells. In this study, we report that FoxP3+RORγt+ intermediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49a7598de07bbbb17d9d59b4aff8a70
https://doi.org/10.4049/jimmunol.0903324
https://doi.org/10.4049/jimmunol.0903324
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(2)
Neonatal immunity exhibits weak Th1 but excessive Th2 responses, and the underlying mechanisms remain elusive. In this article, we show that neonatal basophils readily produce IL-4, a cytokine that proved to be pivotal in shaping the programs of both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38f0b0f052340981d83d5e0bbb87190
https://pubmed.ncbi.nlm.nih.gov/26034171
https://pubmed.ncbi.nlm.nih.gov/26034171
Autor:
Adam A. Zaghouani, Habib Zaghouani, Marie Therese Khairallah, Weirong Chen, Jason A. Cascio, Mermagya Dhakal, Xiaoxiao Wan, Christine M. Hoeman
Upon exposure to Ag on the day of birth, neonatal mice mount balanced primary Th1 and Th2 responses, with the former displaying upregulated IL-13Rα1 expression. This chain associates with IL-4Rα to form a heteroreceptor (IL-4Rα/IL-13Rα1) that mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282c6ef60bfcbcba36a0676f859f5bed
https://europepmc.org/articles/PMC3679234/
https://europepmc.org/articles/PMC3679234/
Autor:
Cara L. Haymaker, Xiaoxiao Wan, Sarah Zaghouani, Christine M. Hoeman, Danielle M. Tartar, Amie M. VanMorlan, Mermagya Dhakal, Habib Zaghouani, Linda M. Rowland, John C. Hardaway, Jason A. Cascio, F. Betul Guloglu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 188(7)
The earliest thymic progenitors (ETPs) were recently shown to give rise to both lymphoid and myeloid cells. Whereas the majority of ETPs are derived from IL-7Rα–positive cells and give rise exclusively to T cells, the origin of the myeloid cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ac32cb4d3159f4a1f306bc5cdc64e9
https://pubmed.ncbi.nlm.nih.gov/22351937
https://pubmed.ncbi.nlm.nih.gov/22351937