Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Merlin Paz"'
Autor:
Eduardo Gomez-Bañuelos, Yikai Yu, Jessica Li, Kevin S. Cashman, Merlin Paz, Maria Isabel Trejo-Zambrano, Regina Bugrovsky, Youliang Wang, Asiya Seema Chida, Cheryl A. Sherman-Baust, Dylan P. Ferris, Daniel W. Goldman, Erika Darrah, Michelle Petri, Iñaki Sanz, Felipe Andrade
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Antibodies directed against DNA in systemic lupus erythematosus are functionally diverse. This study demonstrates that DNAse1L3 is the primary target of a subset of autoantibodies previously considered specific for double-stranded DNA.
Externí odkaz:
https://doaj.org/article/0f1da98ab1e94d54a8c743920c6857c6
Autor:
Eduardo Gomez-Bañuelos, M. Javad Wahadat, Jessica Li, Merlin Paz, Brendan Antiochos, Alessandra Ida Celia, Victoria Andrade, Dylan P. Ferris, Daniel W. Goldman, Erika Darrah, Michelle Petri, Felipe Andrade
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
The origin and mechanisms of autoantigen generation in systemic lupus erythematosus (SLE) are poorly understood. Here, we identified SLE neutrophils activated in vivo by IFN as a prominent source of Ro52, also known as tripartite motif–containing p
Externí odkaz:
https://doaj.org/article/f1b228d8d0914f8591299716f70f3efc
Autor:
Eduardo Gomez-Bañuelos, Linda Johansson, Maximilian F. Konig, Anders Lundquist, Merlin Paz, Kåre Buhlin, Anders Johansson, Solbritt Rantapää-Dahlqvist, Felipe Andrade
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 6, p 1906 (2020)
Periodontal disease has been implicated in the pathogenesis of rheumatoid arthritis (RA), an autoimmune disease characterized by immune-mediated synovial damage, and antibodies to citrullinated antigens. Here, we investigate the association between e
Externí odkaz:
https://doaj.org/article/8e6235eb006142d6807b19f70ca8c2a1
Autor:
Syed Muhammad Hussain Zaidi, Peter A Iskander, Khalid Ahmed, Fouad Jaber, Merlin Paz, Ali Khan, Fahad Malik, Mark M Aloysius
Publikováno v:
Cureus.
Autor:
Sherman-Baust C, Jessica Li, Maria Isabel Trejo-Zambrano, Felipe Andrade, Eduardo Gómez-Bañuelos, Erika Darrah, Merlin Paz, Iñaki Sanz, Daniel W. Goldman, Chida As, Ferris Dp, Regina Bugrovsky, Yuan Yu, Michelle Petri, Kevin S. Cashman, Yun F. Wang
DNase1L3 deficiency is an inborn error of immunity that causes monogenic systemic lupus erythematosus (SLE) in humans. Here, we identified that one third of patients with sporadic SLE have antibodies to DNase1L3. Like DNase1L3 deficiency, we found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b2d8cda6073a4361df65ae010493693
https://doi.org/10.1101/2021.06.07.21258180
https://doi.org/10.1101/2021.06.07.21258180
Autor:
Brendan, Antiochos, Merlin, Paz, Jessica, Li, Daniel W, Goldman, Michelle, Petri, Erika, Darrah, Kevin, Cashman, Ignacio, Sanz, Kathleen H, Burns, Daniel, Ardeljan, Felipe, Andrade, Antony, Rosen
Publikováno v:
Clinical and Experimental Rheumatology.
Long Interspersed Element 1 (LINE-1) is an endogenous retroelement that constitutes a significant portion of the human genome and has been implicated in the pathogenesis of systemic lupus erythematosus (SLE). The LINE-1 RNA chaperone protein ORF1p wa