Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Merlijn J. Meens"'
Autor:
Simon Cuhlmann, Willy Gsell, Kim Van der Heiden, Josef Habib, Jordi L. Tremoleda, Magdy Khalil, Federico Turkheimer, Merlijn J. Meens, Brenda R. Kwak, Joseph Bird, Anthony P. Davenport, John Clark, Dorian Haskard, Rob Krams, Hazel Jones, Paul C. Evans
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Noninvasive imaging methods are required to monitor the inflammatory content of atherosclerotic plaques. FEDAA1106 (N-(5-fluoro- 2-phenoxyphenyl)- N -(2-(2-fluoroethoxy)-5-methoxybenzyl) acetamide) is a selective ligand for TSPO-18kDa (also known as
Externí odkaz:
https://doaj.org/article/9af240ddb9254772a44d051e519cd85a
Autor:
Merlijn J Meens, Issa Kutkut, Viviane Rochemont, Juan Dubrot, Fouad R Kaladji, Amélie Sabine, Oliver Lyons, Stefanie Hendrikx, Jeremiah Bernier-Latmani, Friedemann Kiefer, Alberto Smith, Stéphanie Hugues, Tatiana V Petrova, Brenda R Kwak
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181476 (2017)
Mutations in the gap junction protein connexin47 (Cx47) are associated with lymphedema. However, the role of Cx47 in lymphatic pathophysiology is unknown. We demonstrate that Cx47 is expressed in lymphatic endothelial cells by whole-mount immunostain
Externí odkaz:
https://doaj.org/article/a58386ada0284764b9d7766a9a49caf0
Autor:
Avigail Ehrlich, Brenda R. Kwak, Stéphanie Hugues, Laurent Vinet, Vincent Braunersreuther, Merlijn J. Meens, Graziano Pelli, Osman Ratib, Eliana Scemes, Marc Chanson, Juan Dubrot, Filippo Molica, Christel L Roth, Sandrine Morel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports, Vol. 7, No 1 (2017) P. 13706
Scientific Reports
Scientific Reports, Vol. 7, No 1 (2017) P. 13706
Extracellular ATP is a central signaling molecule in inflammatory responses. Pannexin1 (Panx1) channels release ATP in a controlled manner and have been implicated in various inflammatory pathologies, but their role in atherogenesis remains elusive.
Autor:
Paul M. H. Schiffers, Stephan L. M. Peters, Ben J. A. Janssen, Jo G. R. De Mey, Jelly Nelissen, Léon J. A. Spijkers, Pieter Lemkens, Merlijn J. Meens
Publikováno v:
Hypertension research, 40(8), 738-745. Nature Publishing Group
Hypertension Research, 40(8), 738-745. Nature Publishing Group
Hypertension Research, Vol. 40, No 8 (2017) pp. 738-745
Lemkens, P, Spijkers, L J, Meens, M J, Nelissen, J, Janssen, B, Peters, S L, Schiffers, P M & De Mey, J G 2017, ' Dual NEP/ECE inhibition improves endothelial function in mesenteric resistance arteries of 32-week-old SHR ', Hypertension Research, vol. 40, pp. 738-745 . https://doi.org/10.1038/hr.2017.38
Hypertension Research, 40(8), 738-745. Nature Publishing Group
Hypertension Research, Vol. 40, No 8 (2017) pp. 738-745
Lemkens, P, Spijkers, L J, Meens, M J, Nelissen, J, Janssen, B, Peters, S L, Schiffers, P M & De Mey, J G 2017, ' Dual NEP/ECE inhibition improves endothelial function in mesenteric resistance arteries of 32-week-old SHR ', Hypertension Research, vol. 40, pp. 738-745 . https://doi.org/10.1038/hr.2017.38
Endothelin 1 (ET-1), a potent vasoconstrictor, pro-mitogenic and pro-inflammatory peptide, may promote development of endothelial dysfunction and arterial remodeling. ET-1 can be formed through cleavage of big-ET-1 by endothelin-converting enzyme (EC
Autor:
Graziano Pelli, Beat A. Imhof, Filippo Molica, Sandrine Morel, Brenda R. Kwak, Aurélie Hautefort, Pierre Fontana, Merlijn J. Meens, Yalin Emre, Eliana Scemes
Publikováno v:
Thrombosis Research, Vol. 183 (2019) pp. 56-62
Background Hemostasis is a tightly regulated physiological process to rapidly induce hemostatic plugs at sites of vascular injury. Inappropriate activation of this process may lead to thrombosis, i.e. pathological blood clot formation in uninjured ve
Autor:
Wouter H. Lamers, Ramesh Chennupati, Ben J. A. Janssen, Merlijn J. Meens, S. Eleonore Koehler, Jo G. R. De Mey, Paul van Dijk, Theodorus B. M. Hakvoort
Publikováno v:
Chennupati, R, Meens, M J, Janssen, B J, van Dijk, P, Hakvoort, T B M, Lamers, W H, De Mey, J G R & Koehler, S E 2018, ' Deletion of endothelial arginase 1 does not improve vasomotor function in diabetic mice ', Physiological Reports, vol. 6, no. 11, e13717 . https://doi.org/10.14814/phy2.13717
Physiological Reports, Vol. 6, No 11 (2018) P. e13717
Physiological reports, 6(11):e13717. John Wiley and Sons Inc.
Physiological Reports, 6(11):13717. Wiley
Physiological Reports, Vol. 6, No 11 (2018) P. e13717
Physiological reports, 6(11):e13717. John Wiley and Sons Inc.
Physiological Reports, 6(11):13717. Wiley
Endothelial arginase 1 was ablated to assess whether this prevents hyperglycemia-induced endothelial dysfunction by improving arginine availability for nitric oxide production. Endothelial Arg1-deficient mice (Arg1-KOT ie2) were generated by crossing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebf144d14f51ce845b7dfb407282a35
https://findresearcher.sdu.dk:8443/ws/files/141351715/Deletion_of_endothelial_arginase_1_does_not_improve_vasomotor_function_in_diabetic_mice.pdf
https://findresearcher.sdu.dk:8443/ws/files/141351715/Deletion_of_endothelial_arginase_1_does_not_improve_vasomotor_function_in_diabetic_mice.pdf
Publikováno v:
Cellular and molecular life sciences : CMLS
Connexins and pannexins form connexons, pannexons and membrane channels, which are critically involved in many aspects of cardiovascular physiology. For that reason, a vast number of studies have addressed the role of connexins and pannexins in the a
Autor:
Marie-Luce Bochaton-Piallat, Merlijn J. Meens, Issa Kutkut, Brenda R. Kwak, Thomas Alexander Mckee
Publikováno v:
European journal of clinical investigation
BACKGROUND Atherosclerosis is a chronic inflammatory disease of large to medium sized arteries and is the main underlying cause of death worldwide. The lymphatic vasculature is critical for processes that are intimately linked to atherogenesis such a
Autor:
Marc Chanson, Paul F. Bradfield, Hannah Monyer, Sandrine Morel, Jean François Denis, Merlijn J. Meens, Brenda R. Kwak, Beat A. Imhof, Filippo Molica, Anne Zufferey, Silvia Penuela, Dale W. Laird, Pierre Fontana
Publikováno v:
Thrombosis and haemostasis
Thrombosis and Haemostasis, Vol. 114, No 2 (2015) pp. 325-36
Anatomy and Cell Biology Publications
Thrombosis and Haemostasis, Vol. 114, No 2 (2015) pp. 325-36
Anatomy and Cell Biology Publications
SummaryPannexin1 (Panx1) forms ATP channels that play a critical role in the immune response by reinforcing purinergic signal amplification in the immune synapse. Platelets express Panx1 and given the importance of ATP release in platelets, we invest
The endothelium, a monolayer of cells that lines blood vessels, acts as a physical barrier between circulating blood and vascular smooth muscle cells. The purpose of this chapter is to provide a general overview on the structural heterogeneity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd35039499d28602fe7972df391f361
https://doi.org/10.1093/med/9780198755777.003.0006
https://doi.org/10.1093/med/9780198755777.003.0006