Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Merle Schanz"'
Autor:
Magdalena Schwarzmüller, Cristina Lozano, Merle Schanz, Irene A. Abela, Silvan Grosse-Holz, Selina Epp, Martina Curcio, Jule Greshake, Peter Rusert, Michael Huber, Roger D. Kouyos, Huldrych F. Günthard, Alexandra Trkola
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101702- (2024)
Summary: The development of broadly neutralizing antibody (bnAb)-based therapeutic HIV-1 vaccines and cure concepts depends on monitoring bnAb plasma activity in people with HIV (PWH) on suppressive antiretroviral therapy (ART). To enable this, analy
Externí odkaz:
https://doaj.org/article/a726c3b8bb5347b0a26db15a5cdb413e
Autor:
Liridona Maliqi, Nikolas Friedrich, Matthias Glögl, Stefan Schmutz, Daniel Schmidt, Peter Rusert, Merle Schanz, Maryam Zaheri, Chloé Pasin, Cyrille Niklaus, Caio Foulkes, Thomas Reinberg, Birgit Dreier, Irene Abela, David Peterhoff, Alexandra Hauser, Roger D. Kouyos, Huldrych F. Günthard, Marit J. van Gils, Rogier W. Sanders, Ralf Wagner, Andreas Plückthun, Alexandra Trkola
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Understanding the balance between epitope shielding and accessibility on HIV-1 envelope (Env) trimers is essential to guide immunogen selection for broadly neutralizing antibody (bnAb) based vaccines. To investigate the antigenic space of En
Externí odkaz:
https://doaj.org/article/3c1b7ec8277b4efcb7d60e82c1710437
Autor:
Sarah R Haile, Milo Alan Puhan, Anja Frei, Agne Ulyte, Christoph Berger, Susi Kriemler, Thomas Radtke, Michael Huber, Merle Schanz, Magdalena Schwarzmueller, Alexandra Trkola, Jan Fehr, Irene Alma Abela, Jacob Blankenberger, Ruedi Jung, Celine Capelli
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Objectives To determine the variation in SARS-CoV-2 seroprevalence in school children and the relationship with self-reported symptoms.Design Baseline measurements of a longitudinal cohort study (Ciao Corona) from June to July 2020.Setting 55 schools
Externí odkaz:
https://doaj.org/article/1700a19e521b4d53932e6812efaba54c
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-14 (2018)
Abstract The elicitation of broadly neutralizing antibodies (bnAbs) is considered crucial for an effective, preventive HIV-1 vaccine. Led by the discovery of a new generation of potent bnAbs, the field has significantly advanced over the past decade.
Externí odkaz:
https://doaj.org/article/b9dfcb43a2f542fda1f5fb5ec74e9ad6
Autor:
Lucia Reh, Carsten Magnus, Merle Schanz, Jacqueline Weber, Therese Uhr, Peter Rusert, Alexandra Trkola
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1004966 (2015)
An increasing number of broadly neutralizing antibodies (bnAbs) are considered leads for HIV-1 vaccine development and novel therapeutics. Here, we systematically explored the capacity of bnAbs to neutralize HIV-1 prior to and post-CD4 engagement and
Externí odkaz:
https://doaj.org/article/f95b332dd1594795b01b513f98c525e0
Autor:
Merle Schanz, Thomas Liechti, Osvaldo Zagordi, Enkelejda Miho, Sai T Reddy, Huldrych F Günthard, Alexandra Trkola, Michael Huber
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111726 (2014)
The humoral immune response plays a critical role in controlling infection, and the rapid adaptation to a broad range of pathogens depends on a highly diverse antibody repertoire. The advent of high-throughput sequencing technologies in the past deca
Externí odkaz:
https://doaj.org/article/81676c4c854d43f3976282fd007619e7
Autor:
Irene A Abela, Livia Berlinger, Merle Schanz, Lucy Reynell, Huldrych F Günthard, Peter Rusert, Alexandra Trkola
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002634 (2012)
HIV is known to spread efficiently both in a cell-free state and from cell to cell, however the relative importance of the cell-cell transmission mode in natural infection has not yet been resolved. Likewise to what extent cell-cell transmission is v
Externí odkaz:
https://doaj.org/article/ba48bc4372024adcbbf88ce1f5700063
Autor:
Michael Huber, Milo A. Puhan, Merle Schanz, Ruedi Jung, Celine Capelli, Jan Fehr, Anja Frei, Susi Kriemler, Irene A Abela, Magdalena Schwarzmueller, Thomas Radtke, Alexandra Trkola, Agne Ulyte, Jacob Blankenberger, Christoph Berger, Sarah R. Haile
Publikováno v:
BMJ Open
BMJ Open, Vol 11, Iss 7 (2021)
BMJ Open, Vol 11, Iss 7 (2021)
ObjectivesTo determine the variation in SARS-CoV-2 seroprevalence in school children and the relationship with self-reported symptoms.DesignBaseline measurements of a longitudinal cohort study (Ciao Corona) from June to July 2020.Setting55 schools st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3ce515d3e025657f9f06ae60ab3130
https://www.zora.uzh.ch/id/eprint/210780/
https://www.zora.uzh.ch/id/eprint/210780/
Autor:
L. Maliqi, Alexander Wepf, Irene A Abela, Aline Wolfensberger, Peter Rusert, Maria C Hesselman, Dominique L Braun, Silvana K. Rampini, Eméry Schindler, Huldrych F. Günthard, Merle Schanz, Magdalena Schwarzmüller, Maddalena Marconato, Stefan Schmutz, Jochen Gottschalk, Michèle E Sickmann, Michael Huber, Alexandra Trkola, Selina Epp, Roger D. Kouyos, Urs Karrer, Patrick M. Meyer Sauteur, Annette Audigé, Chloé Pasin, Cyrille R Niklaus, Christoph Berger, Beat Frey, Jürg Böni, Jacqueline Weber, Annika Hunziker, Markus G. Manz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Determination of SARS-CoV-2 antibody responses in the context of pre-existing immunity to circulating human coronavirus (HCoV) is critical for understanding protective immunity. Here we perform a multifactorial analysis of SARS-CoV-2 and HCoV antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a907a7db66f1c92574676b8d61113008
https://doi.org/10.1101/2021.04.21.21255410
https://doi.org/10.1101/2021.04.21.21255410
Autor:
Thomas Radtke, Merle Schanz, Magdalena Schwarzmueller, Agne Ulyte, Michael Huber, Irene A Abela, Sarah R. Haile, Alexandra Trkola, Milo A. Puhan, Susi Kriemler, Christoph Berger, Jan Fehr
Publikováno v:
The BMJ
Objectives To examine longitudinal changes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence and to determine the clustering of children who were seropositive within school classes in the canton of Zurich, Switzerland fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a404b7fd323829b13852887362cca3c9
https://doi.org/10.5167/uzh-210779
https://doi.org/10.5167/uzh-210779