Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Merle Nebel"'
Autor:
Merle Nebel, Viktor Háda, Zoltán Urbányi, Tamás Schäfer, Róbert Kiss, Helga Hevér, Tanja Stadie, Piroska Kovács, Sonja Klingelhöfer
Publikováno v:
Biodrugs
Background In January 2017, the European Commission approved Terrosa® (company code RGB-10) as one of the first biosimilar medicinal products of teriparatide for the same indications as for the reference medicinal product Forsteo® (Lilly France S.A
Autor:
Andreas H. Guse, Alexander Flügel, Barry V. L. Potter, Francesca Odoardi, Bo Zhang, Merle Nebel
Publikováno v:
Nebel, M, Zhang, B, Odoardi, F, Flugel, A, Potter, B & Guse, A H 2015, ' Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation ', Messenger, vol. 4, no. 1, pp. 104-111 . https://doi.org/10.1166/msr.2015.1045
Nicotinic acid adenine dinucleotide phosphate (NAADP) has been implicated as an initial Ca2+ trigger in T cell Ca2+ signalling, but its role in formation of the immune synapse in CD4+ effector T cells has not been analysed. CD4+ T cells are activated
Publikováno v:
DNA Repair. 23:69-78
Strong β-adrenergic stimulation induced spontaneous diastolic Ca(2+) transients (SCTs) in electrically paced murine cardiac myocytes [28]. To obtain further insights into the underlying mechanism, we developed a method for a simultaneous analysis, i
Autor:
Joanna M. Swarbrick, Ralf Fliegert, Barry V. L. Potter, Lucie Carrier, Alexander P. Schwoerer, Martin Hohenegger, Lena Herich, Susan Schlegel, Andreas H. Guse, Karin Weber, Cornelia C. Siebrands, Merle Nebel, Soeren Bruhn, Thomas Eschenhagen, Heimo Ehmke, Anne Geisler, Dominik Warszta, Ann-Christin Limbrock
Publikováno v:
The Journal of Biological Chemistry
Background: Initial studies on cardiac NAADP signaling were published, but no role for NAADP in cardiac arrhythmias has been reported. Results: NAADP affects spontaneous diastolic Ca2+ transients in cardiac myocytes and arrhythmias in awake mice. Con
Autor:
Klaus Dornmair, Barry V. L. Potter, Detlev Schild, Esther Breunig, Dimtri Lodygin, Chiara Cordiglieri, Alexander Flügel, Naoto Kawakami, Wolfgang E. F. Klinkert, Vijay Kumar Ulaganathan, Werner Dammermann, Merle Nebel, Andreas H. Guse, Fred Lühder, Francesca Odoardi, Bo Zhang
Publikováno v:
Brain
Cordiglieri, C, Odoardi, F, Zhang, B, Nebel, M, Kawakami, N, Klinkert, W E F, Lodygin, D, Luhder, F, Breunig, E, Schild, D, Ulaganathan, V K, Dornmair, K, Dammermann, W, Potter, B V L, Guse, A H & Flugel, A 2010, ' Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system ', Brain, vol. 133, no. 7, pp. 1930-1943 . https://doi.org/10.1093/brain/awq135
Cordiglieri, C, Odoardi, F, Zhang, B, Nebel, M, Kawakami, N, Klinkert, W E F, Lodygin, D, Luhder, F, Breunig, E, Schild, D, Ulaganathan, V K, Dornmair, K, Dammermann, W, Potter, B V L, Guse, A H & Flugel, A 2010, ' Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system ', Brain, vol. 133, no. 7, pp. 1930-1943 . https://doi.org/10.1093/brain/awq135
Nicotinic acid adenine dinucleotide phosphate represents a newly identified second messenger in T cells involved in antigen receptor-mediated calcium signalling. Its function in vivo is, however, unknown due to the lack of biocompatible inhibitors. U
Autor:
Alexander Flügel, Angelika Harneit, Barry V. L. Potter, Francesca Odoardi, Cornelia C. Siebrands, Christelle Moreau, Gerd K. Wagner, Merle Nebel, Ralf Fliegert, Tanja Kirchberger, Frederike Schmid, Andreas H. Guse
Publikováno v:
Biochemical Journal
cADPR (cyclic ADP-ribose) is a universal Ca(2+) mobilizing second messenger. In T-cells cADPR is involved in sustained Ca(2+) release and also in Ca(2+) entry. Potential mechanisms for the latter include either capacitative Ca(2+) entry, secondary to
Autor:
James Dowden, Frederike Schmid, Andreas H. Guse, Francesca Odoardi, Naoto Kawakami, Bo Zhang, Chiara Cordiglieri, Martin Hohenegger, Werner Dammermann, Merle Nebel, Klaus Dornmair, Tanja Kirchberger, Barry V. L. Potter, Alexander Flügel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
The nucleotide NAADP was recently discovered as a second messenger involved in the initiation and propagation of Ca 2+ signaling in lymphoma T cells, but its impact on primary T cell function is still unknown. An optimized, synthetic, small molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2ef62988734c1d635f11dc0fc46946
https://hdl.handle.net/11858/00-001M-0000-0012-206B-C11858/00-001M-0000-0012-206C-A
https://hdl.handle.net/11858/00-001M-0000-0012-206B-C11858/00-001M-0000-0012-206C-A
Autor:
Frederike Schmid, Tanja Kirchberger, Chiara Cordiglieri, Werner Dammermann, Barry V. L. Potter, Andreas H. Guse, Merle Nebel, Francesca Odoardi, Bo Zhang, Alexander Flügel
Publikováno v:
GBM Fall meeting Hamburg 2007. 2007
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.