Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Merle M. Weitzenberg"'
Autor:
Casper de Boer, Zachary Armstrong, Vincent A. J. Lit, Uri Barash, Gijs Ruijgrok, Ilanit Boyango, Merle M. Weitzenberg, Sybrin P. Schröder, Alexi J. C. Sarris, Nico J. Meeuwenoord, Pedro Bule, Yasmine Kayal, Neta Ilan, Jeroen D. C. Codée, Israel Vlodavsky, Herman S. Overkleeft, Gideon J. Davies, Liang Wu
Publikováno v:
Proceedings of the National Academy of Sciences, 119(31):e2203167119
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
Heparan sulfate proteoglycans (HSPGs) mediate essential interactions throughout the extracellular matrix (ECM), providing signals that regulate cellular growth and development. Altered HSPG composition during tumorigenesis strongly aids cancer progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e0f15bcd9fafc729176249766a6689
http://hdl.handle.net/1887/3453332
http://hdl.handle.net/1887/3453332
Autor:
Christiane Metz-Weidmann, Elsa Pflimlin, Kerstin Jahn-Hofmann, Ziyu Li, Bodo Brunner, Sabine Scheidler, Armin Hofmeister, Merle M Weitzenberg, Arne Krack, Mike W Helms, Oliver Plettenburg, Michael Kurz
Publikováno v:
Journal of Medicinal Chemistry. 64:6838-6855
A morpholine-based nucleotide analog was developed as a building block for hepatic siRNA targeting and stabilization. Attachment of an asialoglycoprotein-binding GalNAc ligand at the morpholine nitrogen was realized with different linkers. The obtain