Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Merle Hirschmann"'
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Akademický článek
LuxS-dependent AI-2 production is not involved in global regulation of natural product biosynthesis in Photorhabdus and Xenorhabdus
Autor: Antje K. Heinrich, Merle Hirschmann, Nick Neubacher, Helge B. Bode
Publikováno v: PeerJ, Vol 5, p e3471 (2017)
The Gram-negative bacteria Photorhabdus and Xenorhabdus are known to produce a variety of different natural products (NP). These compounds play different roles since the bacteria live in symbiosis with nematodes and are pathogenic to insect larvae in
Externí odkaz: https://doaj.org/article/e9fe5eb85513400eb48eccb8cc4dae55
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2
Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate‐Containing Natural Products in Diverse Bacteria
Autor: Yi‐Ming Shi, Jan J. Crames, Laura Czech, Kenan A. J. Bozhüyük, Yan‐Ni Shi, Merle Hirschmann, Stefanie Lamberth, Peter Claus, Nicole Paczia, Christian Rückert, Jörn Kalinowski, Gert Bange, Helge B. Bode
Publikováno v: Angew Chem Int Ed Engl
Angew Chem Int Ed
Benzoxazolinate is a rare bis-heterocyclic moiety that interacts with proteins and DNA and confers extraordinary bioactivities on natural products, such as C-1027. However, the biosynthetic gene responsible for the key cyclization step of benzoxazoli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2153ac05f1058eb653b781766675d0bf
https://doi.org/10.1002/anie.202206106
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3
Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria
Autor: Yi-Ming Shi, Merle Hirschmann, Yan-Ni Shi, Shabbir Ahmed, Desalegne Abebew, Nicholas J. Tobias, Peter Grün, Jan J. Crames, Laura Pöschel, Wolfgang Kuttenlochner, Christian Richter, Jennifer Herrmann, Rolf Müller, Aunchalee Thanwisai, Sacha J. Pidot, Timothy P. Stinear, Michael Groll, Yonggyun Kim, Helge B. Bode
Publikováno v: Nature Chemistry
Nat Chem
Microorganisms contribute to the biology and physiology of eukaryotic hosts and affect other organisms through natural products. Xenorhabdus and Photorhabdus (XP) living in mutualistic symbiosis with entomopathogenic nematodes generate natural produc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ebd9cea9fd140424a73059eec83e36
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4
Identification and occurrence of the hydroxamate siderophores aerobactin, putrebactin, avaroferrin and ochrobactin C as virulence factors from entomopathogenic bacteria
Autor: Florian Grundmann, Helge B. Bode, Merle Hirschmann
Publikováno v: Environmental Microbiology. 19:4080-4090
Summary Effective iron acquisition and fine-tuned intracellular iron storage systems are the main prerequisites for a successful host invasion by a pathogen. Bacteria have developed several different strategies to sequester this essential element fro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9cff0265e18a6184decd7a05f86f9dc9
https://doi.org/10.1111/1462-2920.13845
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8
LuxS-dependent AI-2 production is not involved in global regulation of natural product biosynthesis in Photorhabdus and Xenorhabdus
Autor: Helge B. Bode, Merle Hirschmann, Nick Neubacher, Antje K. Heinrich
Publikováno v: PeerJ
PeerJ, Vol 5, p e3471 (2017)
The Gram-negative bacteriaPhotorhabdusandXenorhabdusare known to produce a variety of different natural products (NP). These compounds play different roles since the bacteria live in symbiosis with nematodes and are pathogenic to insect larvae in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323cbd743628763fd624ea44d1a7aeb0
http://europepmc.org/articles/PMC5488855
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9
Identification and occurrence of the hydroxamate siderophores aerobactin, putrebactin, avaroferrin and ochrobactin C as virulence factors from entomopathogenic bacteria
Autor: Merle, Hirschmann, Florian, Grundmann, Helge B, Bode
Publikováno v: Environmental microbiology. 19(10)
Effective iron acquisition and fine-tuned intracellular iron storage systems are the main prerequisites for a successful host invasion by a pathogen. Bacteria have developed several different strategies to sequester this essential element from their
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e92add6f8adde0c6ceb6953563a604f2
https://pubmed.ncbi.nlm.nih.gov/28654175
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10
Cleavage Off-Loading and Post-assembly-Line Conversions Yield Products with Unusual Termini during Biosynthesis
Autor: Yi-Ming Shi, Merle Hirschmann, Yan-Ni Shi, Helge B. Bode
Publikováno v: ACS Chem Biol
Piscibactins and photoxenobactins are metallophores and virulence factors, whose biosynthetic gene cluster, termed pxb, is the most prevalent polyketide synthase/non-ribosomal peptide synthetase hybrid cluster across entomopathogenic bacteria. They a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8861e501a1a80963e072f03c84fc2a0
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