Zobrazeno 1 - 10
of 1 345
pro vyhledávání: '"Merle G"'
Publikováno v:
The Scientific World Journal, Vol 10, Pp 1473-1482 (2010)
Prolonged exposure of developing mammals to general anesthetics affects the N-methyl-D-aspartate (NMDA)–type glutamate or γ-aminobutyric acid (GABA) receptor systems and enhances neuronal toxicity. Stimulation of immature neurons by NMDA antagonis
Externí odkaz:
https://doaj.org/article/59c6743a5005445193a2a45c949c7d19
Autor:
Fang eLiu, Meena eMahmood, Yang eXu, Fumiya eWatanabe, Alexandru S Biris, Deborah K hansen, Amy eInselman, Daniel eCasciano, Tucker A Patterson, Merle G Paule, William eSlikker Jr, Cheng eWang
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Silver nano-particles (Ag-NPs) are becoming increasingly prevalent in consumer products as antibacterial agents. The increased use of Ag NP-enhanced products will almost certainly increase environmental silver levels, resulting in increased exposures
Externí odkaz:
https://doaj.org/article/af1fc2cb39554cc680745539524eb7e2
Autor:
Shuliang eLiu, Merle G Paule, Xuan eZhang, Glenn eNewport, Tucker A. Patterson, Scott eApana, Marc eBerridge, Mackean Peter Maisha, William eSlikker Jr, Cheng eWang
Publikováno v:
Frontiers in Neurology, Vol 5 (2014)
Neural progenitor cell expansion is critical for normal brain development and an appropriate response to injury. During the brain growth spurt, exposures to general anesthetics which either block the N-methyl D-aspartate receptor or enhance the γ-am
Externí odkaz:
https://doaj.org/article/25c13adb7725434c8feb555f451ac97f
Autor:
Xiaoxia Yang, Suzanne M Morris, Jeffery M Gearhart, Christopher D Ruark, Merle G Paule, William Slikker, Donald R Mattison, Benedetto Vitiello, Nathan C Twaddle, Daniel R Doerge, John F Young, Jeffrey W Fisher
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106101 (2014)
The widespread usage of methylphenidate (MPH) in the pediatric population has received considerable attention due to its potential effect on child development. For the first time a physiologically based pharmacokinetic (PBPK) model has been developed
Externí odkaz:
https://doaj.org/article/b5b645e24fba41e9a37210a41f624b02
Autor:
Syed Z Imam, William Trickler, Shinya Kimura, Zbigniew K Binienda, Merle G Paule, William Slikker, Senlin Li, Robert A Clark, Syed F Ali
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65129 (2013)
Experimental evidence suggests that oxidative and nitrative mechanisms account for much of the dopaminergic neuronal injury in Parkinson's disease (PD). The ubiquitously expressed non-receptor tyrosine kinase c-Abl is activated by oxidative stress an
Externí odkaz:
https://doaj.org/article/06c1d181ea50456b80141dd97ee14b40
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54927 (2013)
The sexually dimorphic nucleus of the preoptic area (SDN-POA) has received increased attention due to its apparent sensitivity to estrogen-like compounds found in food and food containers. The mechanisms that regulate SDN-POA volume remain unclear as
Externí odkaz:
https://doaj.org/article/e796eb574ac04f25827843fe1513234d
Autor:
Syed Jafar Mehdi, Hector Rosas-Hernandez, Elvis Cuevas, Susan M. Lantz, Steven W. Barger, Sumit Sarkar, Merle G. Paule, Syed F. Ali, Syed Z. Imam
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 9, p 1585 (2016)
Currently, the lack of new drug candidates for the treatment of major neurological disorders such as Parkinson’s disease has intensified the search for drugs that can be repurposed or repositioned for such treatment. Typically, the search focuses o
Externí odkaz:
https://doaj.org/article/abcda3fa228b4d7ba7c44f1aa5a6fd6d
Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for develop
Autor:
Young, Jeffrey T., Vlasova, Roza M., Howell, Brittany R., Knickmeyer, Rebecca C., Morin, Elyse, Kuitchoua, Kaela I., Lubach, Gabriele R., Noel, Jean, Hu, Xiaoping, Shi, Yundi, Caudill, Gibson, Alexander, Andrew L., Niethammer, Marc, Paule, Merle G., Coe, Christopher L., Sanchez, Mar, Styner, Martin
Publikováno v:
In British Journal of Anaesthesia April 2021 126(4):845-853
Autor:
Warner, David O., Chelonis, John J., Paule, Merle G., Frank, Ryan D., Lee, Minji, Zaccariello, Michael J., Katusic, Slavica K., Schroeder, Darrell R., Hanson, Andrew C., Schulte, Phillip J., Wilder, Robert T., Sprung, Juraj, Flick, Randall P.
Publikováno v:
In British Journal of Anaesthesia April 2019 122(4):470-479